Back to search

Asian‐Pacific consensus statement on the management of chronic hepatitis B: a 2005 update

Data up to Jan 2025

Published2005
Citations380
References170

Total Citations Per Year

Abstract

References (170)

Chronic hepatitis B

2007 • 3,079 citations

Lamivudine for Patients with Chronic Hepatitis B and Advanced Liver Disease

2004 • 2,260 citations

A One-Year Trial of Lamivudine for Chronic Hepatitis B

1998 • 1,779 citations

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

1982 • 1,429 citations

Adefovir Dipivoxil for the Treatment of Hepatitis B e Antigen–Positive Chronic Hepatitis B

2003 • 1,354 citations

Hepatitis B e Antigen and the Risk of Hepatocellular Carcinoma

2002 • 1,212 citations

Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial

2005 • 1,154 citations

Peginterferon Alfa-2a Alone, Lamivudine Alone, and the Two in Combination in Patients with HBeAg-Negative Chronic Hepatitis B

2004 • 1,138 citations

LAMIVUDINE AS INITIAL TREATMENT FOR CHRONIC HEPATITIS B IN THE UNITED STATES

1999 • 1,119 citations

HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)

2002 • 1,059 citations

Adefovir Dipivoxil for the Treatment of Hepatitis B e Antigen–Negative Chronic Hepatitis B

2003 • 1,016 citations

Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B

2000 • 940 citations

Reactivation of hepatitis B virus replication in patients receiving cytotoxic therapy

1991 • 827 citations

Long-Term Follow-up of HBeAg-Positive Patients Treated with Interferon Alfa for Chronic Hepatitis B

1996 • 821 citations

Long-term safety of lamivudine treatment in patients with chronic hepatitis B

2003 • 773 citations

Histological outcome during long-term lamivudine therapy

2003 • 734 citations

Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B

2002 • 709 citations

Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues

1999 • 674 citations

Prevalence and Clinical Correlates of YMDD Variants during Lamivudine Therapy for Patients with Chronic Hepatitis B

2003 • 644 citations

Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: Results after 3 years of therapy

2001 • 641 citations

Frequency of hepatitis B virus reactivation in cancer patients undergoing cytotoxic chemotherapy: A prospective study of 626 patients with identification of risk factors

2000 • 627 citations

The development of cirrhosis in patients with chronic type B hepatitis: A prospective study

1988 • 621 citations

Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase

2003 • 575 citations

Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B 1 1The Adefovir Dipivoxil International 461 Study Group includes the following: N. Afdhal (Beth Israel Deaconess Medical Center, Boston, MA); P. Angus (Austin and Repatriation Medical Centre, Melbourne, Australia); Y. Benhamou (Hopital La Pitie Salpetriere, Paris, France); M. Bourliere (Hopital Saint Joseph, Marseille, France); P. Buggisch (Universitaetsklinikum Eppendorf, …

2003 • 568 citations

A critical review of the diagnosis and management of Barrett’s esophagus: the AGA Chicago Workshop1 1Members of the workshop composed a group of international experts in BE from gastroenterology, surgery, pathology, molecular biology, outcomes, and epidemiology. Conference chairman: Prateek Sharma; conference moderator: Kenneth McQuaid; group leaders: John Dent, M. Brian Fennerty, Richard Sampliner, Stuart Spechler; participants: Alan Cameron, Douglas Corley, Gary Falk, John Goldblum, John …

2004 • 537 citations

Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy

1999 • 516 citations

Chronic hepatitis B: Update of recommendations

2004 • 507 citations

Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: a randomised trial

2000 • 503 citations

Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma

2004 • 492 citations

Peginterferon α‐2a (40 kDa): an advance in the treatment of hepatitis B e antigen‐positive chronic hepatitis B

2003 • 483 citations

Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis befficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis befficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis befficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B …

1999 • 481 citations

Hepatitis B genotypes and the response to interferon therapy

2000 • 470 citations

Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C

2002 • 468 citations

Early is superior to deferred preemptive lamivudine therapy for hepatitis B patients undergoing chemotherapy

2003 • 453 citations

Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection

1999 • 450 citations

Influence of human immunodeficiency virus infection on chronic hepatitis B in homosexual men

1999 • 436 citations

IMPACT OF PRETRANSPLANT RENAL FUNCTION ON SURVIVAL AFTER LIVER TRANSPLANTATION

1995 • 434 citations

Long-term incidence of hepatitis B virus resistance to lamivudine in human immunodeficiency virus-infected patients

1999 • 431 citations

Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants

2000 • 426 citations

A Multicenter United States—Canadian Trial to Assess Lamivudine Monotherapy Before and After Liver Transplantation for Chronic Hepatitis B

2001 • 424 citations

EASL INTERNATIONAL CONSENSUS CONFERENCE ON HEPATITIS B13–14 September, 2002Geneva, Switzerland

2003 • 424 citations

Lamivudine treatment for decompensated cirrhosis resulting from chronic hepatitis B

2000 • 422 citations

Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan

2001 • 418 citations

Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease

2003 • 410 citations

Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus

2003 • 404 citations

Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection

2004 • 401 citations

A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C

2001 • 400 citations

Hepatitis B virus genotypes

2004 • 399 citations

Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre- and post-liver transplantation patients

2003 • 377 citations

Efficacy of Long-Term Lamivudine Monotherapy in Patients With Hepatitis B e Antigen–Negative Chronic Hepatitis B

2000 • 365 citations

Hepatitis B e Antigen Seroconversion After Lamivudine Therapy Is Not Durable in Patients With Chronic Hepatitis B in Korea

2000 • 343 citations

Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study

2002 • 335 citations

Hepatitis B viral genotypes: Clinical relevance and molecular characteristics

2002 • 335 citations

Long-term follow-up of alpha-interferon treatment of patients with chronic hepatitis B

2004 • 327 citations

Prognosis following spontaneous HBsAg seroclearance in chronic hepatitis B patients with or without concurrent infection

2002 • 324 citations

Safety and efficacy of adefovir dipivoxil in patients co-infected with HIV-1 and lamivudine-resistant hepatitis B virus: an open-label pilot study

2001 • 316 citations

Clinical Trial of Lamivudine in Children with Chronic Hepatitis B

2002 • 315 citations

Hepatitis B virus genotypes in the United States: results of a nationwide study

2003 • 314 citations

HBV genotype B is associated with better response to interferon therapy in HBeAg(+) chronic hepatitis than genotype C

2002 • 308 citations

Predictors of HBeAg loss after lamivudine treatment for chronic hepatitis B

2002 • 306 citations

Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B

1999 • 300 citations

Lamivudine treatment during pregnancy to prevent perinatal transmission of hepatitis B virus infection

2003 • 293 citations

Profile, spectrum and significance of HBV genotypes in chronic liver disease patients in the Indian subcontinent

2002 • 293 citations

Prospective Study of Hepatocellular Carcinoma and Liver Cirrhosis in Asymptomatic Chronic Hepatitis B Virus Carriers

1997 • 293 citations

Long-term benefit of interferon α therapy of chronic hepatitis D: regression of advanced hepatic fibrosis

2004 • 285 citations

Natural history of hepatitis b e antigen to antibody seroconversion in patients with normal serum aminotransferase levels

2004 • 284 citations

Steroid-free chemotherapy decreases risk of hepatitis B virus (HBV) reactivation in HBV-carriers with lymphoma

2003 • 280 citations

A Randomized, Controlled Trial of Combination Therapy for Chronic Hepatitis B: Comparing Pegylated Interferon-α2b and Lamivudine with Lamivudine Alone

2005 • 278 citations

Determinants of early mortality in patients with decompensated chronic hepatitis B treated with antiviral therapy

2002 • 269 citations

Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine

2004 • 259 citations

Lamivudine for the Prevention of Hepatitis B Virus Reactivation in Hepatitis B s-Antigen Seropositive Cancer Patients Undergoing Cytotoxic Chemotherapy

2004 • 259 citations

Long-term follow-up of patients with anti-HBe/HBV DNA-positive chronic hepatitis B treated for 12 months with lamivudine

2000 • 246 citations

Role of hepatitis C virus in dual and triple hepatitis virus infection*1

1995 • 242 citations

HBsAg seroclearance in chronic hepatitis B in the Chinese: Virological, histological, and clinical aspects

2004 • 238 citations

The long-term outcome of interferon-α treated and untreated patients with HbeAg-negative chronic hepatitis B

2001 • 231 citations

Hepatitis B virus genotypes and virologic response in 694 patients in phase III studies of adefovir dipivoxil1 1Gilead Sciences gratefully acknowledges the patients, investigators, and study site personnel who participated in clinical trials GS-98-437 and GS-98-438.

2003 • 229 citations

Acute Exacerbation of Chronic Hepatitis B Virus Infection After Withdrawal of Lamivudine Therapy

2000 • 223 citations

Interferon α Treatment and Retreatment of Hepatitis B e Antigen-Negative Chronic Hepatitis B

2001 • 220 citations

Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy

2000 • 220 citations

Determinants for sustained HBeAg response to lamivudine therapy

2003 • 218 citations

Clinical relevance of hepatitis B virus genotype in children with chronic infection and hepatocellular carcinoma

2004 • 216 citations

Epidemiologic and virologic characteristics of hepatitis B virus genotype B having the recombination with genotype C

2003 • 205 citations

Preemptive use of lamivudine reduces hepatitis B exacerbation after allogeneic hematopoietic cell transplantation

2002 • 190 citations

Lamivudine treatment in patients with severely decompensated cirrhosis due to replicating hepatitis B infection

2000 • 187 citations

Chronic Active Hepatitis B Exacerbations in Human Immunodeficiency Virus‐Infected Patients Following Development of Resistance to or Withdrawal of Lamivudine

1999 • 179 citations

A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum

1997 • 178 citations

Primary prophylaxis with lamivudine of hepatitis B virus reactivation in chronic HbsAg carriers with lymphoid malignancies treated with chemotherapy

2001 • 177 citations

Resolution of chronic hepatitis B and anti-HBs seroconversion in humans by adoptive transfer of immunity to hepatitis B core antigen

2002 • 175 citations

Effects of Lamivudine on Replication of Hepatitis B Virus in HIV-Infected Men

1996 • 175 citations

Hepatitis B virus genotypes and spontaneous hepatitis B e antigen seroconversion in Taiwanese hepatitis B carriers

2004 • 169 citations

Immunization with an adjuvant hepatitis B vaccine after liver transplantation for hepatitis B–related disease

2003 • 168 citations

Natural course after the development of cirrhosis in patients with chronic type B hepatitis: a prospective study

1989 • 165 citations

Hepatitis B virus genotypes: Do they play a role in the outcome of HBV infection?

2004 • 165 citations

Preemptive lamivudine therapy based on HBV DNA level in HBsAg-positive kidney allograft recipients

2002 • 159 citations

A case-control study for differences among hepatitis B virus infections of genotypes A (subtypes Aa and Ae) and D

2004 • 153 citations

Interferon alfa for chronic hepatitis B infection: Increased efficacy of prolonged treatment

1999 • 153 citations

Beneficial effects of lamivudine in hepatitis B virus-related decompensated cirrhosis

2000 • 152 citations

The multicenter AIDS Cohort Study, 1983 to …

2011 • 148 citations

Hepatitis flares and hepatitis B e antigen seroconversion: Implication in anti‐hepatitis B virus therapy1

2003 • 147 citations

Sustained response after a 2‐year course of lamivudine treatment of hepatitis B e antigen‐negative chronic hepatitis B

2004 • 140 citations

A phase II dose-escalating trial of clevudine in patients with chronic hepatitis B

2004 • 138 citations

Treatment of chronic liver diseases with traditional Chinese medicine

2000 • 137 citations

Mechanisms of Action of Interferons

1989 • 135 citations

Treatment of chronic type B and C hepatitis with interferon alfa: An economic appraisal

1995 • 131 citations

Efficacy of thymosin ?1 in patients with chronic hepatitis B: A randomized, controlled trial

1998 • 125 citations

HBV genotype B is associated with better response to interferon therapy in HBeAg( + ) chronic hepatitis than genotype C

2002 • 123 citations

Long-term efficacy of interferon alpha-2b and lamivudine in combination compared to lamivudine monotherapy in patients with chronic hepatitis B. An Italian multicenter, randomized trial

2001 • 122 citations

EASL INTERNATIONAL CONSENSUS CONFERENCE ON HEPATITIS B

2003 • 122 citations

The effect of lamivudine therapy in hepatic decompensation during acute exacerbation of chronic hepatitis B

2003 • 112 citations

Lamivudine/interferon combination therapy in anti-HBe positive chronic hepatitis B patients: a controlled pilot study

2002 • 98 citations

Asian‐Pacific consensus statement on the management of chronic hepatitis B: An update*

2003 • 98 citations

Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: Analysis of intrahepatic replicative hepatitis B virus DNA

1985 • 97 citations

Varied assembly and RNA editing efficiencies between genotypes I and II hepatitis D virus and their implications

2002 • 87 citations

Prevalence of hepatitis C virus infection in patients with antiphospholipid syndrome

1999 • 87 citations

Prednisolone Priming Enhances Th1 Response and Efficacy of Subsequent Lamivudine Therapy in Patients With Chronic Hepatitis B

2000 • 86 citations

Interferon alfa treatment of chronic hepatitis B: Randomized trial in a predominantly homosexual male population

1995 • 86 citations

A randomised double-blind phase II study of lamivudine (LAM) compared to lamivudine plus adefovir dipovoxil (ADV) for treatment naïve patients with chronic hepatitis B (CHB): Week 52 analysis

2003 • 82 citations

Interferon-α for HBeAg-positive chronic hepatitis B

2003 • 82 citations

S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-xS

2004 • 81 citations

The efficacy of thymosin in the treatment of chronic hepatitis B virus infection: a meta‐analysis

2001 • 79 citations

No Benefit to Continue Lamivudine Therapy after Emergence of Ymdd Mutations

2004 • 79 citations

Immunization with an adjuvant hepatitis B vaccine after liver transplantation for hepatitis B-related disease

2003 • 78 citations

QUALITY OF LIFE IMPROVEMENTS AT ONE, TWO, AND FIVE YEARS AFTER LIVER TRANSPLANTATION1,2

1995 • 76 citations

Hepatitis B Virus RNA Transcripts and DNA in Chronic Liver Disease

1986 • 75 citations

Development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B

2003 • 73 citations

Beneficial effect of prednisolone withdrawal followed by human lymphoblastoid interferon on the treatment of chronic type B hepatitis in Asians: a randomized controlled trial

1994 • 68 citations

Results of lamivudine trials in Asia

2003 • 66 citations

A United States compassionate use study of lamivudine treatment in nontransplantation candidates with decompensated hepatitis B virus–related cirrhosis

2003 • 64 citations

Role of hepatitis C virus in dual and triple hepatitis virus infection

1995 • 64 citations

Retreatment of chronic hepatitis B e antigen-positive patients with recombinant interferon alfa-2a

1999 • 58 citations

Response of Patients with Dual Hepatitis B Virus and C Virus Infection to Interferon Therapy

1997 • 57 citations

Prednisolone withdrawal therapy enhances the effect of human lymphoblastoid interferon in chronic hepatitis B

1996 • 52 citations

Combination low‐dose lymphoblastoid interferon and thymosin α1 therapy in the treatment of chronic hepatitis B

1996 • 52 citations

Chinese Herbal Medicine and Interferon in the Treatment of Chronic Hepatitis B: A Meta-Analysis of Randomized, Controlled Trials

2002 • 51 citations

Core promoter mutations (A1762T and G1764A) and viral genotype in chronic hepatitis B and hepatocellular carcinoma in Guangxi, China

2002 • 47 citations

Comparison of long‐term effects of lymphoblastoid interferon alpha and recombinant interferon alpha‐2a therapy in patients with chronic hepatitis B

2004 • 44 citations

Liver transplantation

1997 • 42 citations

219 Results of a one-year international phase IIB comparative trial of telbivudine, lamivudine, and the combination, in patients with chronic hepatitis B

2003 • 39 citations

Lamivudine treatment for hepatitis B reactivation in HBsAg carriers after organ transplantation: A 4‐year experience

2001 • 38 citations

46 Three year study of adefovir dipivoxil (ADV) demonstrates sustained efficacy in presumed precore mutant chronic hepatitis B (CHB) patients in a long term safety and efficacy study (LTSES)

2004 • 37 citations

Prophylaxis with anti-HBs immune globulins and nucleoside analogues after liver transplantation for HBV infection

2003 • 37 citations

Long-term outcomes of thymosin-α1 and interferon α-2b combination therapy in patients with hepatitis B e antigen (HBeAg) negative chronic hepatitis B

2003 • 34 citations

Thymosin‐α1 and famciclovir combination therapy activates T‐cell response in patients with chronic hepatitis B virus infection in immune‐tolerant phase

2002 • 34 citations

Alpha-interferon for chronic active hepatitis B in human immunodeficiency virus-infected patients.

1996 • 34 citations

Clinical course after stopping lamivudine in chronic hepatitis B patients with lamivudine‐resistant mutants

2004 • 30 citations

Pilot study of combination therapy with ribavirin and interferon alfa for the retreatment of chronic hepatitis B e antibody-positive patients

2000 • 30 citations

Interferon monotherapy in chronic hepatitis B

2000 • 29 citations

Drug Treatment of Pediatric Chronic Hepatitis B

2002 • 28 citations

Thymosin-α1 increases intrahepatic NKT cells and CTLs in patients with chronic hepatitis B

2002 • 26 citations

Nucleoside analogues in the treatment of chronic hepatitis B

2000 • 25 citations

382 In vitro characterization and molecular modeling analysis of a novel adefovir resistance mutation RTN236T in the HBV polymerase

2004 • 22 citations

Treatment of chronic type B and C hepatitis with interferon alfa: An economic appraisal*1

1995 • 21 citations

Changes in serum albumin during treatment of chronic hepatitis B with lamivudine: effects of response and emergence of drug resistance

2002 • 20 citations

A 3-year clinical trial of lamivudine in treatment of patients with chronic hepatitis B.

2004 • 20 citations

Use of immunomodulatory therapy (other than interferon) for the treatment of chronic hepatitis B virus infection

2000 • 19 citations

Interferon–Lamivudine Combination is No Better than Lamivudine Alone in Anti-Hbe-Positive Chronic Hepatitis B

2004 • 19 citations

Long‐term evaluation of recombinant interferon α2b in the treatment of patients with hepatitis B e antigen‐negative chronic hepatitis B in Taiwan

2001 • 18 citations

Beneficial effects of ‘lamivudine pulse’ therapy in HBeAg‐positive patients with normal ALT*

2004 • 18 citations

Tenofovir disoproxil fumarate (TDF) suppresses lamivudine-resistant HBV replication in patients co-infected with HIV/HBV

2002 • 16 citations

Is it safe to stop lamivudine after the emergence of YMDD mutants during lamivudine therapy for chronic hepatitis B?

2002 • 14 citations

Chronic hepatitis B: problem patients (including patients with decompensated disease).

1995 • 14 citations

Safety and efficacy of long-term adefovir dipivoxil (ADV) for lamivudine-resistant (LAM-R) HBV in HIV infected patients

2002 • 13 citations

Short-Term Lamivudine Therapy in Patients with Chronic Hepatitis B

2003 • 12 citations

Natural history of hepatitis B surface antigen‐positive cirrhosis in Taiwan: A clinicopathological study

1988 • 12 citations

Role of steroid priming in the treatment of chronic hepatitis B

2000 • 12 citations

Interferon-alfa in the treatment of chronic hepatitis B.

2004 • 11 citations

Reactivation of hepatitis B virus in anti-HBe-positive chronic active type B hepatitis: molecular and immunohistochemical studies.

1988 • 10 citations

Long-term safety of adefovir dipivoxil (ADV) 10 MG once daily for chronic hepatitis B (CHB): An integrated analysis of two phase III studies

2003 • 9 citations

A 12-week clevudine therapy showed durable antiviral activity and normalization of alanine transminase levels for 6 months after discontinuation of treatment in patients with chronic hepatitis B.

2018 • 2 citations

Bile duct leakage on MR cholangiography

2002 • 1 citations

Cited By (0)

No citing papers found in database

Asian‐Pacific consensus statement on the management of chronic hepatitis B: a 2005 update (2005) – Liver International | Metascience Observatory Explorer