Prevalence and Clinical Correlates of YMDD Variants during Lamivudine Therapy for Patients with Chronic Hepatitis B

A One-Year Trial of Lamivudine for Chronic Hepatitis B

1998 • 1,779 citations

LAMIVUDINE AS INITIAL TREATMENT FOR CHRONIC HEPATITIS B IN THE UNITED STATES

1999 • 1,119 citations

Identification and characterization of mutations in hepatitis B virus resistant to lamivudine

1998 • 808 citations

Changes in Plasma HIV-1 RNA and CD4+ Lymphocyte Counts and the Risk of Progression to AIDS

1996 • 748 citations

Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B

2000 • 708 citations

Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: Results after 3 years of therapy

2001 • 641 citations

Rapid Changes in Human Immunodeficiency Virus Type 1 RNA Load and Appearance of Drug-Resistant Virus Populations in Persons Treated with Lamivudine (3TC)

1995 • 524 citations

Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy

1999 • 516 citations

Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: a randomised trial

2000 • 503 citations

Hepatitis-B-virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation

1997 • 456 citations

Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants

2000 • 426 citations

A Multicenter United States—Canadian Trial to Assess Lamivudine Monotherapy Before and After Liver Transplantation for Chronic Hepatitis B

2001 • 424 citations

Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy

2001 • 394 citations

Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region

2001 • 388 citations

Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy

1998 • 378 citations

Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective

1998 • 374 citations

Renal failure after upper gastrointestinal bleeding in cirrhosis: Incidence, clinical course, predictive factors, and short-term prognosis

2001 • 310 citations

Multicenter Study of Lamivudine Therapy for Hepatitis B After Liver Transplantation

1999 • 291 citations

ISOLATION AND CHARACTERISATION OF RESISTANT HERPES SIMPLEX VIRUS AFTER ACYCLOVIR THERAPY

1982 • 239 citations

Acute Exacerbation of Chronic Hepatitis B Virus Infection After Withdrawal of Lamivudine Therapy

2000 • 223 citations

Extended lamivudine retreatment for chronic hepatitis B: Maintenance of viral suppression after discontinuation of therapy

1999 • 198 citations

Selection of hepatitis B virus polymerase mutants with enhanced replication by lamivudine treatment after liver transplantation

2002 • 194 citations

Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir

1991 • 171 citations

Long-term mutation rates in the hepatitis B virus genome

2000 • 150 citations

A Short-Term Clinical Evaluation of L-697,661, a Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase

1993 • 147 citations

Outcome of lamivudine resistant hepatitis B virus infection in the liver transplant recipient

2000 • 137 citations

Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under hbig immunoglobulin after liver transplantation

1999 • 127 citations

Quantitation of Hepatitis B Viremia and Emergence of YMDD Variants in Patients with Chronic Hepatitis B Treated with Lamivudine

1999 • 123 citations

Two Sensitive PCR-Based Methods for Detection of Hepatitis B Virus Variants Associated with Reduced Susceptibility to Lamivudine

1999 • 123 citations

A Ganciclovir-Resistant Clinical Isolate of Human Cytomegalovirus Exhibiting Cross-Resistance to Other DNA Polymerase Inhibitors

1992 • 84 citations

Naturally Occurring Hepatitis B Virus Genomes Bearing the Hallmarks of Retroviral G → A Hypermutation

1997 • 79 citations

Antiviral resistance: mechanisms, clinical significance, and future implications

1996 • 60 citations

Functional analysis of mutations conferring lamivudine resistance on hepatitis B virus.

1999 • 45 citations

Variants of Hepatitis B, C and D Viruses: Molecular Biology and Clinical Significance

1995 • 41 citations

Therapy of chronic hepatitis B virus infection: inhibition of the viral polymerase and other antiviral strategies

1999 • 41 citations

A Placebo Controlled Study of Lamivudine and Interferonalpha-2b in Patients with Chronic Hepatitis B Who PreviouslyFailed Interferon Therapy

1998 • 40 citations

Quantitative Hepatitis B Virus DNA Testing for the Early Prediction of the Maintenance of Response during Lamivudine Therapy in Patients with Chronic Hepatitis B

2001 • 32 citations

Adefovir dipivoxil (ADV) alone and in combination with lamivudine (LAM) suppresses LAM-resistant hepatitis B virus (HBV) replication: 16 week interim analysis

2002 • 28 citations

GS-98-437 a double-blind, randomized, placebo-controlled study of adefovir dipivoxil (ADV) for the treatment of patients with HBeAg+ chronic hepatitis B infection: 48 week results.

2001 • 15 citations

Three years of lamivudine in anti-HBe positive patients decreased virological and biochemical response

2002 • 1 citations