HBV genotype B is associated with better response to interferon therapy in HBeAg( + ) chronic hepatitis than genotype C

A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness

2000 • 923 citations

A Randomized, Controlled Trial of Interferon Alfa-2b Alone and after Prednisone Withdrawal for the Treatment of Chronic Hepatitis B

1990 • 855 citations

Management of hepatitis B: 2000—Summary of a workshop

2001 • 789 citations

Chronic hepatitis B

2001 • 694 citations

Hepatitis B genotypes and the response to interferon therapy

2000 • 470 citations

Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C

2002 • 468 citations

Clinical relevance of hepatitis B viral mutations

2000 • 348 citations

Which patients with chronic hepatitis B virus infection will respond to α-interferon therapy? A statistical analysis of predictive factors

1989 • 306 citations

Predictors of HBeAg loss after lamivudine treatment for chronic hepatitis B

2002 • 306 citations

Different hepatitis b virus genotypes are associated with different mutations in the core promoter and precore regions during hepatitis B e antigen seroconversion

1999 • 266 citations

Clinical significance of hepatitis B virus genotypes

2002 • 256 citations

A controlled trial of interferon with or without prednisone priming for chronic hepatitis B

1992 • 242 citations

Hepatitis B virus unable to secrete e antigen and response to interferon in chronic hepatitis B

1993 • 183 citations

Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B

2000 • 126 citations

Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance

1995 • 67 citations

Consensus statements on the prevention and management of hepatitis B and hepatitis C in the Asia–Pacific region¹

2000 • 64 citations

Subtype‐Dependent Response of Hepatitis B Virus during the Early Phase of Lamivudine Treatment

2002 • 54 citations

The dynamics of mutations in the YMDD motif of the hepatitis B virus polymerase gene during and after lamivudine treatment as determined by reverse hybridisation

2002 • 49 citations

Outcome of liver disease and response to interferon treatment are not influenced by hepatitis B virus core gene variability in children with chronic type B hepatitis

1997 • 20 citations

Mutations in the X region and core promoter are rare and have little impact on response to interferon therapy for chronic hepatitis B

2001 • 15 citations

Effect of multiple mutations in the core promoter and pre‐core/core region of hepatitis B virus genome on the response to interferon in e antigen‐positive chronic hepatitis B

2001 • 9 citations

Distribution and clinical response of HBV genotypes in phase III studies of adefovir dipivoxil

2002 • 4 citations