The Human Ageing Genomic Resources: online databases and tools for biogerontologists

Gene Ontology: tool for the unification of biology

2000 • 38,297 citations

FishBase. World Wide Web electronic publication

2005 • 3,872 citations

Longevity, senescence and the genome

1995 • 1,390 citations

The Plasticity of Aging: Insights from Long-Lived Mutants

2005 • 1,319 citations

Life History Invariants

1993 • 1,134 citations

Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

2003 • 1,114 citations

Inparanoid: a comprehensive database of eukaryotic orthologs

2004 • 756 citations

Life History Invariants: Some Explorations of Symmetry in Evolutionary Ecology

1993 • 721 citations

Strong Variations of Mitochondrial Mutation Rate across Mammals--the Longevity Hypothesis

2007 • 448 citations

The Genetics of Aging

2001 • 445 citations

An Analysis of the Relationship Between Metabolism, Developmental Schedules, and Longevity Using Phylogenetic Independent Contrasts

2007 • 367 citations

Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

2005 • 338 citations

Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms

2007 • 257 citations

Telomerase activity coevolves with body mass not lifespan

2006 • 218 citations

Quantitative evidence for conserved longevity pathways between divergent eukaryotic species

2008 • 200 citations

A modular network model of aging

2007 • 169 citations

Correlates of substitution rate variation in mammalian protein-coding sequences

2008 • 168 citations

HAGR: the Human Ageing Genomic Resources

2004 • 168 citations

No Truth to the Fountain of Youth

2002 • 157 citations

Skin‐derived fibroblasts from long‐lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone

2006 • 156 citations

Genetics of Longevity and Aging

2005 • 147 citations

Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly

2008 • 141 citations

GenAge: a genomic and proteomic network map of human ageing

2004 • 137 citations

DETECTING GENE RELATIONS FROM MEDLINE ABSTRACTS

2000 • 133 citations

Longevity of mammals in captivity; from the Living Collections of the world

2005 • 128 citations

The Influence of Genes on the Aging Process of Mice

2004 • 106 citations

Mitochondrially encoded cysteine predicts animal lifespan

2007 • 102 citations

Longevity network: Construction and implications

2006 • 95 citations

Diverse aging rates in metazoans: targets for functional genomics

2004 • 88 citations

Common gene signature of cancer and longevity

2008 • 55 citations

Open-minded scepticism: inferring the causal mechanisms of human ageing from genetic perturbations

2004 • 55 citations

Direct repeats in mitochondrial DNA and mammalian lifespan

2006 • 44 citations

Analyses of human–chimpanzee orthologous gene pairs to explore evolutionary hypotheses of aging

2007 • 36 citations

Do Mitochondrial DNA and Metabolic Rate Complement Each Other in Determination of the Mammalian Maximum Longevity?

2008 • 36 citations

Life span prolongation

1993 • 27 citations

Species Selection in Comparative Studies of Aging and Antiaging Research

2006 • 25 citations

NOVEL INTEGRATION OF HOSPITAL ELECTRONIC MEDICAL RECORDS AND GENE EXPRESSION MEASUREMENTS TO IDENTIFY GENETIC MARKERS OF MATURATION

2007 • 20 citations

Mitochondrial Genome Anatomy and Species-Specific Lifespan

2006 • 18 citations

A Position Paper on Longevity Genes

2001 • 10 citations

Deleted Work

1955 • 0 citations