Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly

Statistical significance for genomewide studies

2003 • 9,411 citations

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

2000 • 3,126 citations

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

2003 • 2,209 citations

Identifying biological themes within lists of genes with EASE

2003 • 1,969 citations

A Model-Based Background Adjustment for Oligonucleotide Expression Arrays

2004 • 1,715 citations

A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changes

2001 • 1,622 citations

Estrogen accelerates cutaneous wound healing associated with an increase in TGF-β1 levels

1997 • 546 citations

Topical Estrogen Accelerates Cutaneous Wound Healing in Aged Humans Associated with an Altered Inflammatory Response

1999 • 407 citations

Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16.

1996 • 401 citations

Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing

2000 • 400 citations

Characterization of E-selectin-deficient mice: Demonstration of overlapping function of the endothelial selectins

1994 • 384 citations

Ageing and wound healing.

2002 • 274 citations

Androgen receptor–mediated inhibition of cutaneous wound healing

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Androgen receptor–mediated inhibition of cutaneous wound healing

2002 • 221 citations

Aging alters the inflammatory and endothelial cell adhesion molecule profiles during human cutaneous wound healing.

1998 • 200 citations

Effect of age on wound healing in healthy human beings.

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Microarray data mining

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HAGR: the Human Ageing Genomic Resources

2004 • 168 citations

A Model Based Background Adjustment for Oligonucleotide Expression Arrays

2004 • 157 citations

Aging is No Longer an Unsolved Problem in Biology

2006 • 156 citations

Using a customized DNA microarray for expression profiling of the estrogen-responsive genes to evaluate estrogen activity among natural estrogens and industrial chemicals.

2004 • 105 citations

Macrophage Migration Inhibitory Factor

2005 • 105 citations

Expression of nitric oxide synthase isoforms and arginase in normal human skin and chronic venous leg ulcers

2000 • 100 citations

Differential Activation of Migration by Hypoxia in Keratinocytes Isolated from Donors of Increasing Age: Implication for Chronic Wounds in the Elderly

2001 • 99 citations

ERGDB: Estrogen Responsive Genes Database

2003 • 92 citations

Using an artificial neural network to predict healing times and risk factors for venous leg ulcers

2002 • 77 citations

Longevity genes: from primitive organisms to humans

2004 • 72 citations

A steroid hormone that extends the lifespan of Caenorhabditis elegans

2006 • 66 citations

Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion

2002 • 53 citations

The Incidence and Risks of Failure to Heal After Lower Extremity Amputation for the Treatment of Diabetic Neuropathic Foot Ulcer

2006 • 49 citations

Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion

2002 • 40 citations

Polymorphisms spanning the 0N exon and promoter of the estrogen receptor‐beta (ERβ) gene ESR2 are associated with venous ulceration

2007 • 38 citations

The dinucleotide (CA) repeat polymorphism of estrogen receptor beta but not the dinucleotide (TA) repeat polymorphism of estrogen receptor alpha is associated with venous ulceration

2005 • 35 citations

Insulin-Degrading Activity in Wound Fluid

2004 • 35 citations

Hormone action in newt limb regeneration: insulin and endorphins

1987 • 15 citations