Regulation of Phospholipase C-β1 by Gq and m1 Muscarinic Cholinergic Receptor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1973 • 2,518 citations

The GTPase superfamily: a conserved switch for diverse cell functions

1990 • 2,330 citations

Baculovirus expression vectors: a laboratory manual.

1992 • 1,799 citations

Heterotrimeric C proteins: Organizers of transmembrane signals

1995 • 1,388 citations

Chemistry of the metal chelate compounds

1953 • 1,006 citations

Baculovirus expression vectors — A laboratory manual

1993 • 886 citations

G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates.

1990 • 463 citations

Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator

1992 • 430 citations

Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.

1986 • 380 citations

Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins.

1987 • 359 citations

Cloning and sequence of multiple forms of phospholipase C

1988 • 342 citations

Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

1992 • 340 citations

Purification of Recombinant G Proteins from Sf9 Cells by Hexahistidine Tagging of Associated Subunits

1995 • 332 citations

Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP

1992 • 324 citations

Antibodies to the alpha q subfamily of guanine nucleotide-binding regulatory protein alpha subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones.

1991 • 320 citations

G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma

1992 • 302 citations

Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells.

1991 • 283 citations

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity.

1992 • 268 citations

The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.

1986 • 261 citations

Catecholamine-stimulated GTPase cycle. Multiple sites of regulation by beta-adrenergic receptor and Mg2+ studied in reconstituted receptor-Gs vesicles.

1986 • 225 citations

Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins.

1985 • 206 citations

An essential role for phosphatidylinositol transfer protein in phospholipase C-Mediated inositol lipid signaling

1993 • 205 citations

Purification and characterization of two G-proteins that activate the beta 1 isozyme of phosphoinositide-specific phospholipase C. Identification as members of the Gq class.

1991 • 191 citations

Mechanisms of muscarinic receptor action on Go in reconstituted phospholipid vesicles

1989 • 180 citations

Phosphatidylinositol transfer protein dictates the rate of inositol trisphosphate production by promoting the synthesis of PIP2

1995 • 157 citations

GTPase activity of the stimulatory GTP-binding regulatory protein of adenylate cyclase, Gs. Accumulation and turnover of enzyme-nucleotide intermediates.

1985 • 143 citations

Regulation of transducin GTPase activity in bovine rod outer segments.

1994 • 131 citations

Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase.

1994 • 115 citations

[19] Synthetic peptide antisera with determined specificity for G protein α or β subunits

1991 • 114 citations

Guanine-nucleotide and hormone regulation of polyphosphoinositide phospholipase C activity of rat liver plasma membranes. Bivalent-cation and phospholipid requirements

1987 • 112 citations

Effects of gelsolin on human platelet cytosolic phosphoinositide-phospholipase C isozymes.

1992 • 94 citations

Muscarinic Receptor‐Mediated Inositol 1,4,5‐Trisphosphate Formation in SH‐SY5Y Neuroblastoma Cells Is Regulated Acutely by Cytosolic Ca²⁺ and by Rapid Desensitization

1994 • 88 citations

Enhanced GTPase activity of transducin when bound to cGMP phosphodiesterase in bovine retinal rods.

1992 • 79 citations

Extraction of polyphosphoinositides with neutral and acidified solvents A comparison of guinea-pig brain and liver, and measurements of rat liver inositol compounds which are resistant to extraction

1970 • 76 citations

Chimeric muscarinic cholinergic:beta-adrenergic receptors that are functionally promiscuous among G proteins.

1994 • 73 citations

Affinity chromatography of the muscarinic acetylcholine receptor.

1983 • 72 citations

An Effector Site That Stimulates G-protein GTPase in Photoreceptors

1995 • 69 citations

GTPase Activating Proteins

1993 • 64 citations

Characterization of Gq Family G Proteins GL1α (G14α), GL2α (G11α), and Gqα Expressed in the Baculovirus-Insect Cell System

1995 • 63 citations

G Protein GTPase-Activating Proteins: Regulation of Speed, Amplitude, and Signaling Selectivity

1995 • 43 citations

The β-Adrenergic Receptor and its Mode of Coupling to Adenylate Cyclas

1981 • 33 citations

Rapid binding of guanosine 5'-0-(3-thiotriphosphate) to an apparent complex of .beta.-adrenergic receptor and the GTP-binding regulatory protein Gs

1988 • 31 citations

[24] Purification and subunit composition of cytochrome c1 from baker's yeast Saccharomyces cerevisiae

1978 • 20 citations

[16] Preparation of guanine nucleotide-free G proteins

1991 • 11 citations