An essential role for phosphatidylinositol transfer protein in phospholipase C-Mediated inositol lipid signaling

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

1991 • 774 citations

Regulation of inositol phospholipid-specific phospholipase C isozymes.

1992 • 740 citations

Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits

1992 • 630 citations

An essential role for a phospholipid transfer protein in yeast Golgi function

1990 • 534 citations

Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C

1992 • 506 citations

PHOSPHOLIPID TRANSFER PROTEINS

1991 • 445 citations

The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex.

1989 • 381 citations

Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors

1992 • 367 citations

Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

1992 • 340 citations

Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells.

1992 • 321 citations

Members of the Gq alpha subunit gene family activate phospholipase C beta isozymes.

1992 • 277 citations

G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells.

1991 • 263 citations

Phospholipid Exchange between Membranes

1974 • 248 citations

Inositol lipids in cell signalling.

1989 • 212 citations

Phosphoinositide kinase, diacylglycerol kinase, and phospholipase C activities associated to the cytoskeleton: effect of epidermal growth factor.

1991 • 202 citations

Interaction of pp60c-src, phospholipase C, inositol-lipid, and diacyglycerol kinases with the cytoskeletons of thrombin-stimulated platelets

1991 • 193 citations

Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.

1992 • 176 citations

Influence of gamma subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes.

1992 • 152 citations

Relationship between phosphatidylinositol synthesis and recovery of 5-hydroxytryptamine-responsive Ca2+ flux in blowfly salivary glands

1979 • 135 citations

Independent phosphatidylinositol synthesis in pituitary plasma membrane and endoplasmic reticulum

1987 • 132 citations

Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O

1988 • 121 citations

The gene encoding the phosphatidylinositol transfer protein is essential for cell growth.

1990 • 118 citations

Isolation and sequence of cDNA clones encoding rat phosphatidylinositol transfer protein

1989 • 114 citations

The relationship of hormone-sensitive and hormone-insensitive phosphatidylinositol to phosphatidylinositol 4,5-bisphosphate in the WRK-1 cell.

1986 • 98 citations

Binding of phospholipids to the phosphatidylinositol transfer protein from bovine brain as studied by steady-state and time-resolved fluorescence spectroscopy

1987 • 75 citations

G-proteins, the inositol lipid signalling pathway, and secretion

1988 • 75 citations

Subcellular localisation of inositol lipid kinases in rat liver

1985 • 74 citations

Accelerated high‐sensitivity microsequencing of proteins and peptides using a miniature reaction cartridge

1992 • 72 citations

Phospholipase C Isozymes: Structural and Functional Similarities

2007 • 57 citations

Subcellular Organization of Receptor-Mediated Phosphoinositide Turnover*

1992 • 50 citations

Identification of a novel cytosolic poly-phosphoinositide-specific phospholipase C (PLC-86) as the major G-protein-regulated enzyme.

1991 • 46 citations

Association of a receptor and G-protein-regulated phospholipase C with the cytoskeleton

1992 • 45 citations

Tissue distribution, purification and characterization of rat phosphatidylinositol transfer protein

1988 • 44 citations

Phosphatidylinositol transfer protein from bovine brain

1983 • 41 citations

The phosphatidylinositol transfer protein in 3T3 mouse fibroblast cells is associated with the Golgi system

1992 • 40 citations

Identification, purification and characterization of a novel phosphatidylinositol‐specific phospholipase C, a third member of the β subfamily

1992 • 33 citations

Inositol lipids: receptor-stimulated hydrolysis and cellular lipid pools

1988 • 32 citations

Membrane phospholipid asymmetry in Semliki Forest virus grown in BHK cells

1989 • 23 citations

The inactivity of brain phospholipid transfer protein toward phosphatidylinositol 4-phosphate

1983 • 17 citations

Characterization of fMet‐Leu‐Phe‐stimulated phospholipase C in streptolysin‐O‐permeabilised cells

1991 • 15 citations

Organization of the phosphoinositide cycle. Assessment of inositol transferase activity in purified plasma membranes

1993 • 14 citations