G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates.

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

Studies of Inositol Phospholipid-Specific Phospholipase C

1989 • 914 citations

Direct Activation of Mammalian Atrial Muscarinic Potassium Channels by GTP Regulatory Protein G _k

1987 • 441 citations

The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway

1987 • 431 citations

GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

1987 • 365 citations

The G protein-gated atrial K+ channel is stimulated by three distinct GIα-subunits

1988 • 306 citations

Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization

1985 • 284 citations

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

1990 • 282 citations

Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.

1987 • 276 citations

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

1988 • 275 citations

The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist.

1988 • 273 citations

G protein multiplicity in eukaryotic signal transduction systems

1988 • 267 citations

Expression of Gsα in Escherichia coli

1989 • 262 citations

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.

1988 • 251 citations

Synthesis in Escherichia coli of GTPase-deficient mutants of Gsα

1989 • 247 citations

Regulation and function of Gα protein subunits in Dictyostelium

1989 • 227 citations

Mutations in the GTP-binding site of GSα alter stimulation of adenylyl cyclase

1989 • 209 citations

Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

1990 • 208 citations

Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

1988 • 207 citations

Coupling of photoexcited rhodopsin to inositol phospholipid hydrolysis in fly photoreceptors.

1987 • 193 citations

Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse.

1989 • 175 citations

Carboxyl Rerminal Domain of G _sα Specifies Coupling of Receptors to Stimulation of Adenylyl Cyclase

1988 • 174 citations

Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go.

1990 • 147 citations

Molecular cloning of a novel splice variant of the alpha subunit of the mammalian Go protein.

1990 • 146 citations

Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf.

1990 • 145 citations

G protein linked signal transduction pathways in development: Dictyostelium as an experimental system

1989 • 144 citations

G protein .beta..gamma. subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of .alpha. subunits by pertussis toxin but differential interactions with Gs.alpha.

1989 • 139 citations

Immunological and Molecular Characterization of Goα-like Proteins in the Drosophila Central Nervous System

1989 • 90 citations

A Drosophila melanogaster G protein alpha subunit gene is expressed primarily in embryos and pupae.

1988 • 85 citations

Functional differences in the .beta..gamma. complexes of transducin and the inhibitory guanine nucleotide regulatory protein

1987 • 76 citations

Thyrotropin-releasing hormone stimulation of polyphosphoinositide hydrolysis in GH3 cell membranes is GTP dependent but insensitive to cholera or pertussis toxin.

1986 • 75 citations

Novel localization of a G protein, Gz-alpha, in neurons of brain and retina

1990 • 74 citations

The Drosophila Go α-like G protein gene produces multiple transcripts and is expressed in the nervous system and in ovaries

1989 • 74 citations

Molecular characterization of Drosophila Gene Encoding G0 α Subunit Homolog

1989 • 72 citations

Isolation of the alpha subunits of GTP-binding regulatory proteins by affinity chromatography with immobilized beta gamma subunits.

1989 • 65 citations

The Drosophila gene coding for the alpha subunit of a stimulatory G protein is preferentially expressed in the nervous system.

1989 • 65 citations

Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit.

1989 • 40 citations