Toward the identification of a tolerogenic signature in IDO-competent dendritic cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

2003 • 10,537 citations

Immunol. Cell Biol.

1995 • 2,564 citations

The Biology of Chemokines and their Receptors

2000 • 2,416 citations

Mouse and human dendritic cell subtypes

2002 • 2,311 citations

Ido expression by dendritic cells: tolerance and tryptophan catabolism

2004 • 2,235 citations

Regulation of immune responses by L-arginine metabolism

2005 • 1,636 citations

IRF Family of Transcription Factors as Regulators of Host Defense

2001 • 1,566 citations

Modulation of tryptophan catabolism by regulatory T cells

2003 • 1,323 citations

Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance

2002 • 1,176 citations

CTLA-4–Ig regulates tryptophan catabolism in vivo

2002 • 1,150 citations

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy

2005 • 1,021 citations

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

1991 • 1,018 citations

Statistical tests for differential expression in cDNA microarray experiments

2003 • 894 citations

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

2004 • 834 citations

Tolerance, DCs and tryptophan: much ado about IDO

2003 • 752 citations

Tryptophan and the immune response

2003 • 725 citations

TREMs in the immune system and beyond

2003 • 665 citations

Dendritic cell lineage, plasticity and cross-regulation

2001 • 613 citations

The Analysis of Gene Expression Data: Methods and Software

2005 • 514 citations

Ligation of B7-1/B7-2 by Human CD4+ T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells

2004 • 459 citations

Characterization of the CD200 Receptor Family in Mice and Humans and Their Interactions with CD200

2003 • 421 citations

IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity

2005 • 403 citations

A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation

2005 • 390 citations

MAANOVA: A Software Package for the Analysis of Spotted cDNA Microarray Experiments

2003 • 325 citations

Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12

2005 • 317 citations

CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86

2004 • 296 citations

Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

2002 • 251 citations

DAP12-Deficient Mice Fail to Develop Autoimmunity Due to Impaired Antigen Priming

2000 • 236 citations

Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: a retrospective analysis.

2003 • 229 citations

A Defect in Tryptophan Catabolism Impairs Tolerance in Nonobese Diabetic Mice

2003 • 213 citations

The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function

2000 • 210 citations

Review: ICSBP/IRF-8: Its Regulatory Roles in the Development of Myeloid Cells

2002 • 192 citations

IL-6 Inhibits the Tolerogenic Function of CD8α+ Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase

2001 • 185 citations

Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells

2004 • 172 citations

Combined Natural Killer Cell and Dendritic Cell Functional Deficiency in KARAP/DAP12 Loss-of-Function Mutant Mice

2000 • 165 citations

KARAP/DAP12/TYROBP: three names and a multiplicity of biological functions

2005 • 152 citations

Relationships Among Murine CD11chigh Dendritic Cell Subsets as Revealed by Baseline Gene Expression Patterns

2003 • 139 citations

Differential regulation of human indoleamine 2,3-dioxygenase gene expression by interferons-gamma and -alpha. Analysis of the regulatory region of the gene and identification of an interferon-gamma-inducible DNA-binding factor.

1993 • 137 citations

Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages

2005 • 129 citations

CTLA-4–Ig Activates Forkhead Transcription Factors and Protects Dendritic Cells from Oxidative Stress in Nonobese Diabetic Mice

2004 • 126 citations

Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors

2005 • 115 citations

Functional Plasticity of Dendritic Cell Subsets as Mediated by CD40 Versus B7 Activation

2003 • 108 citations

Synergistic Activation of Interleukin-12 p35 Gene Transcription by Interferon Regulatory Factor-1 and Interferon Consensus Sequence-binding Protein

2004 • 107 citations

ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells

2003 • 106 citations

IFN-γ Inhibits Presentation of a Tumor/Self Peptide by CD8α− Dendritic Cells Via Potentiation of the CD8α+ Subset

2000 • 101 citations

Regulation of human auto- and alloreactive T cells by indoleamine 2,3-dioxygenase (IDO)–producing dendritic cells: too much ado about IDO?

2004 • 99 citations

Cutting Edge: Silencing Suppressor of Cytokine Signaling 3 Expression in Dendritic Cells Turns CD28-Ig from Immune Adjuvant to Suppressant

2005 • 91 citations

Intracellular Signaling by the Killer Immunoglobulin-Like Receptors and Ly49

2001 • 89 citations

Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation

2005 • 51 citations

Differential Regulation of DAP12 and Molecules Associated with DAP12 during Host Responses to Mycobacterial Infection

2004 • 44 citations

Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12

2005 • 40 citations

The Role of the DAP12 Signal in Mouse Myeloid Differentiation

2000 • 40 citations

CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig

2005 • 24 citations

Effect of Iron Intake on Control of Body Iron in Patients with Thalassemia Major Treated with Deferasirox (Exjade®, ICL670).

2005 • 15 citations

Deferasirox (Exjade®, ICL670) Demonstrates Dose-Related Effects on Body Iron Levels Related to Transfusional Iron Intake in Transfusion-Dependent Anemia.

2005 • 10 citations