Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 729 citations

NEW EMBO MEMBERS' REVIEW: Lysosomal cysteine proteases: facts and opportunities

2001 • 723 citations

Regulation of B Lymphocyte and Macrophage Development by Graded Expression of PU.1

2000 • 712 citations

Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene

1996 • 650 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 637 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

IN VITRO SYNTHESIS AND SECRETION OF LYSOZYME BY MONONUCLEAR PHAGOCYTES

1974 • 525 citations

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

2000 • 420 citations

ICSBP Is Essential for the Development of Mouse Type I Interferon-producing Cells and for the Generation and Activation of CD8α+ Dendritic Cells

2002 • 414 citations

Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPα ratio and granulocyte colony-stimulating factor

2003 • 370 citations

A Cathepsin L Isoform that Is Devoid of a Signal Peptide Localizes to the Nucleus in S Phase and Processes the CDP/Cux Transcription Factor

2004 • 355 citations

Saposin proteins: structure, function, and role in human lysosomal storage disorders

1991 • 328 citations

PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors

2002 • 316 citations

Essential role for ICSBP in the in vivo development of murine CD8α+ dendritic cells

2002 • 313 citations

ICSBP Directs Bipotential Myeloid Progenitor Cells to Differentiate into Mature Macrophages

2000 • 302 citations

IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development

2003 • 262 citations

Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta.

1993 • 251 citations

PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene

2000 • 244 citations

Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.

1996 • 237 citations

Cutting Edge: IFN Consensus Sequence Binding Protein/IFN Regulatory Factor 8 Drives the Development of Type I IFN-Producing Plasmacytoid Dendritic Cells

2003 • 229 citations

Lack of Interferon Consensus Sequence Binding Protein (ICSBP) Transcripts in Human Myeloid Leukemias

1998 • 207 citations

Review: ICSBP/IRF-8: Its Regulatory Roles in the Development of Myeloid Cells

2002 • 192 citations

PU.1, Interferon Regulatory Factor 1, and Interferon Consensus Sequence-binding Protein Cooperate to Increase gp91 Expression

1998 • 178 citations

Expression of Interferon Consensus Sequence Binding Protein (ICSBP) Is Downregulated in Bcr-Abl-Induced Murine Chronic Myelogenous Leukemia-Like Disease, and Forced Coexpression of ICSBP Inhibits Bcr-Abl-Induced Myeloproliferative Disorder

2000 • 150 citations

BLIMP-1: trigger for differentiation of myeloid lineage

2000 • 148 citations

Protein-Protein and DNA-Protein Interactions Affect the Activity of Lymphoid-Specific IFN Regulatory Factors

1999 • 135 citations

Bacterial Killing Is Enhanced by Expression of Lysozyme in the Lungs of Transgenic Mice

2000 • 119 citations

Altered Development and Cytokine Responses of Myeloid Progenitors in the Absence of Transcription Factor, Interferon Consensus Sequence Binding Protein

1999 • 107 citations

Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2

2003 • 103 citations

IFN-Stimulated Gene 15 Is Synergistically Activated Through Interactions Between the Myelocyte/Lymphocyte-Specific Transcription Factors, PU.1, IFN Regulatory Factor-8/IFN Consensus Sequence Binding Protein, and IFN Regulatory Factor-4: Characterization of a New Subtype of IFN-Stimulated Response Element

2002 • 102 citations

An Induced Ets Repressor Complex Regulates Growth Arrest during Terminal Macrophage Differentiation

2002 • 101 citations

DNA Binding Specificity Studies of Four ETS Proteins Support an Indirect Read-out Mechanism of Protein-DNA Recognition

2000 • 95 citations

IFN Consensus Sequence Binding Protein/IFN Regulatory Factor-8 Guides Bone Marrow Progenitor Cells Toward the Macrophage Lineage

2002 • 87 citations

Negative Regulation of Epidermal Growth Factor Signaling by Selective Proteolytic Mechanisms in the Endosome Mediated by Cathepsin B

1999 • 86 citations

Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-α

2001 • 83 citations

The importance of PU.1 concentration in hematopoietic lineage commitment and maturation

2003 • 80 citations

Endosomal Proteolysis of Internalized Insulin at the C-terminal Region of the B Chain by Cathepsin D

2002 • 77 citations

Interferon Consensus Sequence Binding Protein and Interferon Regulatory Factor-4/Pip Form a Complex That Represses the Expression of the Interferon-Stimulated Gene-15 in Macrophages

1999 • 73 citations

Gamma Interferon Triggers Interaction between ICSBP (IRF-8) and TEL, Recruiting the Histone Deacetylase HDAC3 to the Interferon-Responsive Element

2002 • 67 citations

PU.1, a Shared Transcriptional Regulator of Lymphoid and Myeloid Cell Fates

1999 • 65 citations

ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells

2003 • 63 citations

Interferon consensus sequence binding protein: Not essential for interferon alpha-mediated antiviral response to vesicular-stomatitis virus infection in HL-60 cells

2001 • 60 citations

The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15Ink4b in murine myeloid cells

2004 • 57 citations

Activated Fes Protein Tyrosine Kinase Induces Terminal Macrophage Differentiation of Myeloid Progenitors (U937 Cells) and Activation of the Transcription Factor PU.1

2002 • 49 citations

Accumulation of c-Cbl and rapid termination of colony-stimulating factor 1 receptor signaling in interferon consensus sequence binding protein–deficient bone marrow–derived macrophages

2002 • 17 citations