Histone Deacetylase 1 Can Repress Transcription by Binding to Sp1

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1998 • 3,363 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Histone acetylation in chromatin structure and transcription

1997 • 2,834 citations

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1998 • 2,686 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 • 1,769 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

1997 • 1,251 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

Retinoblastoma protein recruits histone deacetylase to repress transcription

1998 • 1,231 citations

A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

1997 • 1,218 citations

Roles of histone acetyltransferases and deacetylases in gene regulation

1998 • 1,207 citations

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1998 • 1,091 citations

Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia

1998 • 1,021 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

1997 • 945 citations

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1998 • 919 citations

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1997 • 856 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities

1998 • 791 citations

Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

1997 • 739 citations

The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity

1996 • 705 citations

Sp1-mediated transcriptional activation is repressed by Sp3.

1994 • 692 citations

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1996 • 623 citations

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

1998 • 587 citations

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

1997 • 565 citations

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

1996 • 541 citations

Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines

1997 • 480 citations

Isolation and Characterization of cDNAs Corresponding to an Additional Member of the Human Histone Deacetylase Gene Family

1997 • 431 citations

A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase

1998 • 426 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

A role for histone deacetylase activity in HDAC1-mediated transcriptional repression

1998 • 363 citations

Interaction of Sp1 with the Growth- and Cell Cycle-Regulated Transcription Factor E2F

1996 • 343 citations

Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase

1998 • 318 citations

RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae.

1991 • 315 citations

Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1.

1993 • 310 citations

Reduced Retinoic Acid-Sensitivities of Nuclear Receptor Corepressor Binding to PML- and PLZF-RARα Underlie Molecular Pathogenesis and Treatment of Acute Promyelocytic Leukemia

1998 • 303 citations

Histone Deacetylase: A Regulator of Transcription

1996 • 298 citations

Characterization of a human RPD3 ortholog, HDAC3

1998 • 292 citations

Histone Deacetylase Inhibitor Activates the WAF1/Cip1 Gene Promoter through the Sp1 Sites

1997 • 291 citations

SAP30, a Novel Protein Conserved between Human and Yeast, Is a Component of a Histone Deacetylase Complex

1998 • 288 citations

Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein

1998 • 286 citations

Cell Cycle-Regulated Association of E2F1 and Sp1 Is Related to Their Functional Interaction

1996 • 268 citations

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

1998 • 253 citations

An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation.

1994 • 238 citations

Identification of a New Family of Higher Eukaryotic Histone Deacetylases

1999 • 228 citations

Chromatin remodeling and transcription

1997 • 227 citations

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.

1996 • 207 citations

Induction of S-Phase Entry by E2F Transcription Factors Depends on Their Nuclear Localization

1997 • 195 citations

The subcellular localization of E2F-4 is cell-cycle dependent

1997 • 193 citations

HDA1 and HDA3 Are Components of a Yeast Histone Deacetylase (HDA) Complex

1996 • 189 citations

Growth/Cell Cycle Regulation of Sp1 Phosphorylation

1999 • 174 citations

Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast

1987 • 171 citations

Cooperative Interaction between AhR·Arnt and Sp1 for the Drug-inducible Expression of CYP1A1 Gene

1996 • 160 citations

Chromatin: Histone acetyltransferases in control

1997 • 139 citations

Identification of Mouse Histone Deacetylase 1 as a Growth Factor-Inducible Gene

1997 • 117 citations

Differential Display Cloning of a Novel Human Histone Deacetylase (HDAC3) cDNA from PHA-Activated Immune Cells

1998 • 110 citations

Remodeling chromatin structures for transcription: What happens to the histones?

1996 • 110 citations

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

1997 • 99 citations

Transcriptional regulation of the dihydrofolate reductase gene

1996 • 89 citations

Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter

1997 • 71 citations

A comparative study of histone deacetylases of plant, fungal and vertebrate cells

1996 • 71 citations

Simian virus 40 large T antigen associates with cyclin A and p33cdk2

1993 • 41 citations

Factors influencing efficiency and reproducibility of polybrene-assisted gene transfer

1988 • 40 citations

Cell-Growth Regulation of the Hamster Dihydrofolate Reductase Gene Promoter by Transcription Factor Sp1

1997 • 31 citations