Cell-Growth Regulation of the Hamster Dihydrofolate Reductase Gene Promoter by Transcription Factor Sp1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

A simple method of reducing the fading of immunofluorescence during microscopy

1981 • 1,907 citations

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences

1990 • 1,140 citations

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1989 • 1,031 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G₁/S-Regulatory Genes

1995 • 910 citations

ALTERNATIVE SPLICING IN THE CONTROL OF GENE EXPRESSION

1989 • 701 citations

Sp1-mediated transcriptional activation is repressed by Sp3.

1994 • 692 citations

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

1992 • 588 citations

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.

1992 • 587 citations

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.

1988 • 539 citations

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.

1993 • 353 citations

Interaction of Sp1 with the Growth- and Cell Cycle-Regulated Transcription Factor E2F

1996 • 343 citations

A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter.

1993 • 315 citations

Transcription Factor E2F Is Required for Efficient Expression of the Hamster Dihydrofolate Reductase Gene In Vitro and In Vivo

1989 • 292 citations

Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter.

1990 • 270 citations

Cell Cycle-Regulated Association of E2F1 and Sp1 Is Related to Their Functional Interaction

1996 • 268 citations

Effect of gamma rays at the dihydrofolate reductase locus: Deletions and inversions

1986 • 233 citations

Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element.

1994 • 194 citations

The HIP1 Binding Site Is Required for Growth Regulation of the Dihydrofolate Reductase Gene Promoter

1992 • 172 citations

Transcriptional regulation of mouse dihydrofolate reductase in the cell cycle.

1985 • 165 citations

Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo.

1989 • 144 citations

Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein

1994 • 143 citations

Negative regulation of Sp1 trans-activation is correlated with the binding of cellular proteins to the amino terminus of the Sp1 trans-activation domain.

1994 • 128 citations

Functional analysis of GC element binding and transcription in the hamster dihydrofolate reductase gene promoter

1989 • 123 citations

Expression of abbreviated mouse dihydrofolate reductase genes in cultured hamster cells.

1982 • 121 citations

E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection.

1992 • 115 citations

G1/S-regulated E2F-containing protein complexes bind to the mouse thymidine kinase gene promoter.

1994 • 98 citations

Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA.

1993 • 97 citations

Cloning, chromosomal location, and characterization of mouse E2F1.

1994 • 90 citations

Regulation of dihydrofolate reductase gene expression in mouse fibroblasts during the transition from the resting to growing state

1978 • 89 citations

Cell cycle regulation of dihydrofolate reductase mRNA metabolism in mouse fibroblasts.

1980 • 89 citations

Inducible proteins binding to the murine thymidine kinase promoter in late G1/S phase.

1991 • 79 citations

Two promoter-specific host factors interact with adjacent sequences in an EIA-inducible adenovirus promoter.

1987 • 74 citations

In vitro and in vivo analysis of the control of dihydrofolate reductase gene transcription in serum‐stimulated mouse fibroblasts

1984 • 70 citations

Position-Dependent Transcriptional Regulation of the Murine Dihydrofolate Reductase Promoter by the E2F Transactivation Domain

1997 • 62 citations

Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene.

1993 • 55 citations

RNA processing is a limiting step for murine tumor necrosis factor beta expression in response to interleukin-2.

1990 • 52 citations

Murine dihydrofolate reductase transcripts through the cell cycle.

1986 • 52 citations

The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter.

1992 • 51 citations

Deletion analysis of the Chinese hamster dihydrofolate reductase gene promoter.

1988 • 51 citations

PCR with 5-methyl-dCTP replacing dCTP

1991 • 26 citations

Polyadenylation of Chinese hamster dihydrofolate reductase genomic genes and minigenes after gene transfer

1987 • 24 citations

Splicing of the E2A premessenger RNA of adenovirus serotype 2

1986 • 22 citations

Point mutational analysis of the hamster dihydrofolate reductase minimum promoter.

1992 • 19 citations

Use of fluorescence-activated cell sorter to isolate mutant mammalian cells deficient in an internal protein, dihydrofolate reductase

1985 • 18 citations

Identification of the cis-elements required for transcriptional control of the Chinese hamster ovary APRT gene

1995 • 6 citations