Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia.

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1998 • 3,363 citations

Regulation of chromatin structure by site-specific histone H3 methyltransferases

2000 • 2,709 citations

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1998 • 2,686 citations

Methylation-Induced Repression— Belts, Braces, and Chromatin

1999 • 1,823 citations

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA

1992 • 1,331 citations

Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins

1998 • 1,317 citations

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1998 • 1,091 citations

The PHD finger: Implications for chromatin-mediated transcriptional regulation

1995 • 857 citations

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1992 • 850 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

The POZ domain: a conserved protein-protein interaction motif.

1994 • 770 citations

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1991 • 703 citations

Alterations of a Zinc Finger-Encoding Gene, BCL-6 , in Diffuse Large-Cell Lymphoma

1993 • 680 citations

Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

1993 • 584 citations

The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes.

1994 • 560 citations

Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation

1999 • 492 citations

The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila.

1994 • 466 citations

Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31

1999 • 433 citations

SET domain proteins modulate chromatin domains in eu- and heterochromatin

1998 • 374 citations

Sin Meets NuRD and Other Tails of Repression

1999 • 353 citations

Eukaryotic DNA methylation as an evolutionary device

1999 • 328 citations

The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT

1998 • 314 citations

Crystal structure of the BTB domain from PLZF

1998 • 301 citations

The 1.7 Å crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller

1998 • 298 citations

Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators

1998 • 265 citations

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

1998 • 245 citations

Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia

1997 • 212 citations

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

1987 • 208 citations

The Methyl-CpG Binding Transcriptional Repressor MeCP2 Stably Associates with Nucleosomal DNA

1999 • 182 citations

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.

1994 • 175 citations

Chromatin Remodeling and Leukemia: New Therapeutic Paradigms

1999 • 173 citations

Antigens recognized by autologous antibody in patients with renal-cell carcinoma

1999 • 170 citations

13q deletions in lymphoid malignancies

1995 • 137 citations

Evidence for a new tumour suppressor locus (DBM) in human B–cell neoplasia telomeric to the retinoblastoma gene

1993 • 135 citations

Cloning and Gene Mapping of the Chromosome 13q14 Region Deleted in Chronic Lymphocytic Leukemia

1997 • 130 citations

The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution

1996 • 129 citations

High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics

1993 • 127 citations

p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins.

1996 • 127 citations

Sequence of the FRA3B common fragile region: Implications for the mechanism of FHIT deletion

1997 • 120 citations

Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia

1996 • 112 citations

Cytogenetics in chronic lymphocytic leukemia.

1998 • 109 citations

Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: evidence for a role of an adjacent locus.

1993 • 102 citations

Detailed Molecular Delineation of 13q14.3 Loss in B-Cell Chronic Lymphocytic Leukemia

1998 • 101 citations

Cytogenetic and molecular abnormalitiesin chronic lymphocytic leukaemia

1994 • 73 citations

Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene

1996 • 72 citations

RCC1 in the Ran Pathway

1996 • 71 citations

The consistent 13q14 translocation breakpoint seen in chronic B-cell leukaemia (BCLL) involves deletion of the D13S25 locus which lies distal to the retinoblastoma predisposition gene.

1993 • 68 citations

Retinoblastoma gene deletions in b‐cell chronic lymphocytic leukemia

1992 • 67 citations

Heterogeneity of deletions involving RB-1 and the D13S25 locus in B-cell chronic lymphocytic leukemia revealed by fluorescence in situ hybridization.

1995 • 66 citations

A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B‐cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5

1998 • 65 citations

Rubisco Small and Large SubunitN-Methyltransferases

1999 • 62 citations

Frequent homozygous deletions of the D13S25 locus in chromosome region 13q14 defines the location of a gene critical in leukaemogenesis in chronic B-cell lymphocytic leukaemia.

1994 • 59 citations

ALL1 gene alterations in acute leukemia: biological and clinical aspects.

1998 • 57 citations

Interphase cytogenetics in chronic lymphocytic leukemia

1997 • 57 citations

A Novel Human Gene Encoding HECT Domain and RCC1-like Repeats Interacts with Cyclins and Is Potentially Regulated by the Tumor Suppressor Proteins

1999 • 52 citations

Assignment of a novel bifurcated SET domain gene, SETDB1, to human chromosome band 1q21 by in situ hybridization and radiation hybrids

1999 • 50 citations

Construction of a 780-kb PAC, BAC, and Cosmid Contig Encompassing the Minimal Critical Deletion Involved in B Cell Chronic Lymphocytic Leukemia at 13q14.3

1997 • 45 citations

Isolation and mapping of karyopherin α3 (KPNA3), a human gene that is highly homologous to genes encoding <i>Xenopus</i> importin, yeast SRP1 and human RCH1

1997 • 26 citations

cDNA Cloning, Gene Characterization and 13q14.3 Chromosomal Assignment of CHC1-L, a Chromosome Condensation Regulator-like Guanine Nucleotide Exchange Factor

1998 • 20 citations

Exclusion of Leu1 and Leu2 genes as tumor suppressor genes in 13q14.3-deleted B-CLL

1999 • 19 citations

Confirmation of Rb gene defects in B‐CLL clones and evidence for variable predominance of the Rb defective cells within the CLL clone

1993 • 19 citations

Assignment of 48 ESTs to Chromosome 13 Band q14.3 and Expression Pattern for ESTs Located in the Core Region Deleted in B-CLL

1998 • 18 citations

Role of TCL1 and ALL1 in human leukemias and development.

1999 • 15 citations

Molecular and biologic determinants of neoadjuvant chemotherapy of locoregional breast cancer.

1998 • 11 citations

Delineation of the frequently deleted region on chromosome arm 13q in B-cell non-Hodgkin's lymphoma.

2000 • 9 citations

Construction of a bacterial artificial chromosome (BAC) contig across the minimally deleted region in 13q14.3 in B‐cell chronic lymphocytic leukemia

1998 • 3 citations