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A Neural Substrate of Prediction and Reward

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Reinforcement Learning: A Survey

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The neural basis of drug craving: An incentive-sensitization theory of addiction

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Predictive Reward Signal of Dopamine Neurons

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A psychomotor stimulant theory of addiction.

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Synaptic Plasticity and Memory: An Evaluation of the Hypothesis

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Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex

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AMPA Receptor Trafficking and Synaptic Plasticity

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Drug Abuse: Hedonic Homeostatic Dysregulation

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Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

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Drug Dependence, a Chronic Medical Illness

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Cellular and Molecular Mechanisms of Drug Dependence

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Function and Regulation of CREB Family Transcription Factors in the Nervous System

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Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

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A framework for mesencephalic dopamine systems based on predictive Hebbian learning

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Brain Dopamine and Reward

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The Structure of Genetic and Environmental Risk Factors for Common Psychiatric and Substance Use Disorders in Men and Women

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Opioids excite dopamine neurons by hyperpolarization of local interneurons

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Limbic Activation During Cue-Induced Cocaine Craving

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Addiction

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The Neuroscience of Natural Rewards: Relevance to Addictive Drugs

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CREB AND MEMORY

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Addiction and the brain: The neurobiology of compulsion and its persistence

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Acute Effects of Cocaine on Human Brain Activity and Emotion

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The functions of the orbitofrontal cortex

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Addiction, a Disease of Compulsion and Drive: Involvement of the Orbitofrontal Cortex

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Addiction, Dopamine, and the Molecular Mechanisms of Memory

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Drugs of Abuse and Stress Trigger a Common Synaptic Adaptation in Dopamine Neurons

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Evidence for Addiction-like Behavior in the Rat

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Neural Economics and the Biological Substrates of Valuation

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Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway.

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The Basal Ganglia and Chunking of Action Repertoires

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Computational roles for dopamine in behavioural control

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Decreased dopamine D₂ receptor availability is associated with reduced frontal metabolism in cocaine abusers

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Prefrontal Glutamate Release into the Core of the Nucleus Accumbens Mediates Cocaine-Induced Reinstatement of Drug-Seeking Behavior

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Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

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A 33-Year Follow-up of Narcotics Addicts

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Regulation of Cocaine Reward by CREB

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Familial Transmission of Substance Use Disorders

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Memory and Addiction

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Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine

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Drug Seeking Becomes Compulsive After Prolonged Cocaine Self-Administration

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Cortical rewiring and information storage

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Associative Processes in Addiction and Reward The Role of Amygdala‐Ventral Striatal Subsystems

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Conditioning factors in drug abuse: can they explain compulsion?

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Regulation of gene expression and cocaine reward by CREB and ΔFosB

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Drug addiction: bad habits add up

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Cingulate Hypoactivity in Cocaine Users During a GO-NOGO Task as Revealed by Event-Related Functional Magnetic Resonance Imaging

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Neural Activity Related to Drug Craving in Cocaine Addiction

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Neuronal Activity Related to Reward Value and Motivation in Primate Frontal Cortex

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Anterior Cingulate: Single Neuronal Signals Related to Degree of Reward Expectancy

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Addiction as a Computational Process Gone Awry

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Neural Systems and Cue-Induced Cocaine Craving,

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Extrathalamic Modulation of Cortical Function

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Interaction between glucocorticoid hormones, stress and psychostimulant drugs*

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Addictive drugs as reinforcers: multiple partial actions on memory systems

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Computational perspectives on dopamine function in prefrontal cortex

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Neuronal Correlates of Goal-Based Motor Selection in the Prefrontal Cortex

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Genetic and Environmental Influences on Substance Initiation, Use, and Problem Use in Adolescents

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Limbic-Striatal Memory Systems and Drug Addiction

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Neuronal adaptation to amphetamine and dopamine: Molecular mechanisms of prodynorphin gene regulation in rat striatum

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Common Molecular and Cellular Substrates of Addiction and Memory

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Amphetamine regulates gene expression in rat striatum via transcription factor CREB

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Glutamate systems in cocaine addiction

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Drug Dependence, a Chronic Medical Illness: Implications for Treatment, Insurance, and Outcomes Evaluation

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Molecular Neurobiology of Drug Addiction

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A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use

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A Complex Program of Striatal Gene Expression Induced by Dopaminergic Stimulation

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Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine.

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Molecular alterations in the neostriatum of human cocaine addicts

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Amphetamine and Dopamine-Induced Immediate Early Gene Expression in Striatal Neurons Depends on Postsynaptic NMDA Receptors and Calcium

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Sensitization to the psychomotor stimulant effects of amphetamine: Modulation by associative learning.

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Classical conditioning of a morphine abstinence phenomenon, reinforcement of opioid-drinking behavior and ?relapse? in morphine-addicted rats

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Reward without Dopamine

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Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: lack of conditioned effects

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Learning Mechanisms in Addiction: Synaptic Plasticity in the Ventral Tegmental Area as a Result of Exposure to Drugs of Abuse

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Molecular bases of long-term memories: a question of persistence

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The long-term potential of LTP

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Is craving the source of compulsive drug use?

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The role of withdrawal in heroin addiction: enhances reward or promotes avoidance?

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Amphetamine Modulates Human Incentive Processing

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In search of general mechanisms for long-lasting plasticity:Aplysiaand the hippocampus

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The Location of Persistent Amphetamine-Induced Changes in the Density of Dendritic Spines on Medium Spiny Neurons in the Nucleus Accumbens and Caudate-Putamen

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Cocaine-induced potentiation of synaptic strength in dopamine neurons: Behavioral correlates in GluRA(–/–) mice

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Methamphetamine Activates Reward Circuitry in Drug Naïve Human Subjects

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Reinstatement of heroin self-administration habits: morphine prompts and naltrexone discourages renewed responding after extinction

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A psychomotor stimulant theory of addiction.

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Mechanisms by which Dopamine Receptors May Influence Synaptic Plasticity

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Synaptic plasticity in the mesolimbic dopamine system

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Prefrontal Cortical Norepinephrine Release Is Critical for Morphine-induced Reward, Reinstatement and Dopamine Release in the Nucleus Accumbens

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Regulation of kappa opioid receptor mRNA in the rat brain by ‘binge’ pattern cocaine administration and correlation with preprodynorphin mRNA

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Dynorphin regulates D1 dopamine receptor-mediated responses in the striatum: Relative contributions of pre- and postsynaptic mechanisms in dorsal and ventral striatum demonstrated by altered immediate-early gene induction

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Learning and Memory Mechanisms Involved in Compulsive Drug Use and Relapse

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A Man With Alcoholism and HIV Infection

1995 • 10 citations

A man with alcoholism and HIV infection

1995 • 4 citations