Active Repression of Methylated Genes by the Chromosomal Protein MBD1
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Abstract
References (52)
Antibodies, a laboratory manual
1989 • 12,929 citations
Antibodies: A laboratory manual
1989 • 4,532 citations
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1998 • 3,363 citations
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1998 • 2,686 citations
Methylation-Induced Repression— Belts, Braces, and Chromatin
1999 • 1,823 citations
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA
1992 • 1,331 citations
Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins
1998 • 1,317 citations
MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin
1997 • 1,258 citations
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
1999 • 1,068 citations
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
1999 • 898 citations
CpG methylation, chromatin structure and gene silencing---a three-way connection
1998 • 791 citations
Three proteins define a class of human histone deacetylases related to yeast Hda1p
1999 • 744 citations
Effects of DNA methylation on DNA-binding proteins and gene expression
1993 • 732 citations
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
1991 • 722 citations
Reactivation of an Inactive Human X Chromosome: Evidence for X Inactivation by DNA Methylation
1981 • 711 citations
The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression
1993 • 692 citations
Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
1989 • 655 citations
DNA methylation and chromatin modification
1999 • 641 citations
Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal
1993 • 602 citations
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2
1993 • 584 citations
Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.
1992 • 472 citations
Gene number, noise reduction and biological complexity
1995 • 462 citations
Activation of mammalian DNA methyltransferase by cleavage of a Zn binding regulatory domain.
1992 • 454 citations
Displacement of sequence-specific transcription factors from mitotic chromatin
1995 • 444 citations
Isolation and Characterization of cDNAs Corresponding to an Additional Member of the Human Histone Deacetylase Gene Family
1997 • 431 citations
Cytosine methylation and mammalian development
1999 • 384 citations
DNA hypomethylation can activate Xist expression and silence X-linked genes.
1996 • 377 citations
DNA Methylation Specifies Chromosomal Localization of MeCP2
1996 • 343 citations
A 5′ 2-Kilobase-Pair Region of the Imprinted Mouse H19 Gene Exhibits Exclusive Paternal Methylation throughout Development
1997 • 341 citations
Loss of methylation activates Xist in somatic but not in embryonic cells.
1995 • 300 citations
Characterization of a human RPD3 ortholog, HDAC3
1998 • 292 citations
SAP30, a Novel Protein Conserved between Human and Yeast, Is a Component of a Histone Deacetylase Complex
1998 • 288 citations
5-Methylcytosine localised in mammalian constitutive heterochromatin
1974 • 267 citations
A component of the transcriptional represser MeCP1 shares a motif with DNA methyltransferase and HRX proteins
1997 • 242 citations
11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene.
1994 • 241 citations
The solution structure of the domain from MeCP2 that binds to methylated DNA
1999 • 202 citations
Methylation-Mediated Transcriptional Silencing in Euchromatin by Methyl-CpG Binding Protein MBD1 Isoforms
1999 • 198 citations
The Methyl-CpG Binding Transcriptional Repressor MeCP2 Stably Associates with Nucleosomal DNA
1999 • 182 citations
Specific antibodies reveal ordered and cell‐cycle‐related use of histone‐H4 acetylation sites in mammalian cells
1989 • 172 citations
Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia.
1995 • 140 citations
Antibodies to defined histone epitopes reveal variations in chromatin conformation and underacetylation of centric heterochromatin in human metaphase chromosomes
1992 • 128 citations
Histone acetylation: A possible mechanism for the inheritance of cell memory at mitosis
1997 • 121 citations
Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes
1999 • 104 citations
CpG methylation remodels chromatin structure in vitro
1997 • 101 citations
New 5′ Regions of the Murine and Human Genes for DNA (Cytosine-5)-methyltransferase
1996 • 96 citations
Inhibition of promoter activity by methylation: possible involvement of protein mediators.
1991 • 88 citations
New sites of methylcytosine-rich DNA detected on metaphase chromosomes
1994 • 64 citations
Mosaic methylation of the repeat unit of the human ribosomal RNA genes
1997 • 50 citations
Characterisation of Independent DNA and Multiple Zn-binding Domains at the N Terminus of Human DNA-(Cytosine-5) Methyltransferase: Modulating the Property of a DNA-binding Domain by Contiguous Zn-binding Motifs
1996 • 42 citations
Immunofluorescence Techniques Applied to Mitotic Chromosome Preparations
2003 • 14 citations
Does DNA methylation control transposition of selfish elements in the germline? Reply
1997 • 4 citations
Reply
1997 • 3 citations
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