Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

The Inheritance of Epigenetic Defects

1987 • 1,058 citations

DNA methylation and gene activity

1988 • 904 citations

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

1991 • 722 citations

High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines

1990 • 709 citations

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1985 • 668 citations

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

1989 • 655 citations

DNA methylation and the regulation of globin gene expression

1983 • 451 citations

OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts

1987 • 255 citations

Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts

1983 • 255 citations

MECHANISMS OF X-CHROMOSOME REGULATION

1988 • 222 citations

Induction of thymidine kinase in enzyme-deficient chinese hamster cells

1982 • 205 citations

Dynamics of demethylation and activation of the α-actin gene in myoblasts

1990 • 159 citations

Inactivation of the HIV LTR by DNA CpG methylation: evidence for a role in latency.

1990 • 150 citations

Muscle-specific activation of a methylated chimeric actin gene

1986 • 135 citations

DNA methylation and viral gene expression in adenovirus-transformed and-infected cells

1980 • 131 citations

An estrogen-dependent demethylation at the 5′ end of the chicken vitellogenin gene is independent of DNA synthesis

1984 • 106 citations

DNA methylation of three 5' C-C-G-G 3' sites in the promoter and 5' region inactivate the E2a gene of adenovirus type 2.

1984 • 105 citations

Site specific demethylation in the promoter of human gamma-globin gene does not alleviate methylation mediated suppression.

1987 • 105 citations

The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.

1988 • 96 citations

Trans effect of the E1 region of adenoviruses on the expression of a prokaryotic gene in mammalian cells: resistance to 5' -CCGG- 3' methylation.

1986 • 79 citations

Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro.

1989 • 74 citations

Effect of in vitro DNA methylation on beta-globin gene expression.

1988 • 69 citations

Reactivation of the methylation-inactivated late E2A promoter of adenovirus type 2 by E1A (13 S) functions

1988 • 64 citations

Is hypomethylation linked to activation of δ-crystallin genes during lens development?

1983 • 53 citations

In vitrotranscription with extracts of nuclei ofDrosophilaembryos

1985 • 50 citations

Reactivation of the methylation-inhibited late E2A promoter of adenovirus type 2 by a strong enhancer of human cytomegalovirus

1988 • 36 citations

The Coupling Between Enhancer Activity and Hypomethylation of κ Immunoglobulin Genes is Developmentally Regulated

1988 • 36 citations