New 5′ Regions of the Murine and Human Genes for DNA (Cytosine-5)-methyltransferase

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1995 • 2,000 citations

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

1994 • 1,542 citations

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

1995 • 1,353 citations

[31] PHD: Predicting one-dimensional protein structure by profile-based neural networks

1996 • 1,291 citations

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

1987 • 1,088 citations

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

1992 • 1,027 citations

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1988 • 891 citations

Suppression of intestinal neoplasia by DNA hypomethylation

1995 • 712 citations

[24] Rapid amplification of complementary DNA ends for generation of full-length complementary DNAs: Thermal race

1993 • 501 citations

Activation of mammalian DNA methyltransferase by cleavage of a Zn binding regulatory domain.

1992 • 454 citations

DNA methylation and cancer

1994 • 418 citations

DNA methylation errors and cancer.

1996 • 405 citations

Physical mapping across the fragile X: Hypermethylation and clinical expression of the fragile X syndrome

1991 • 357 citations

Increased Cytosine DNA-Methyltransferase Activity During Colon Cancer Progression

1993 • 315 citations

Creation of genomic methylation patterns

1996 • 313 citations

Loss of methylation activates Xist in somatic but not in embryonic cells.

1995 • 300 citations

De Novo Methylation of CpG Island Sequences in Human Fibroblasts Overexpressing DNA (Cytosine-5-)-Methyltransferase

1996 • 290 citations

Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos

1987 • 261 citations

Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.

1995 • 254 citations

Isolation and characterization of the cDNA encoding human DNA methyltransferase

1992 • 250 citations

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.

1996 • 237 citations

DNA methyltransferases

1994 • 237 citations

Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting.

1992 • 228 citations

DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotes

1990 • 227 citations

Regulation of DNA Methylation by the Ras Signaling Pathway

1995 • 190 citations

Regulation of the DNA Methyltransferase by the Ras-AP-1 Signaling Pathway

1995 • 136 citations

DNA Methylation, Genomic Imprinting, and Mammalian Development

1993 • 108 citations

Cytosine methylation The pros and cons of DNA methylation

1993 • 83 citations

The mouse DNA methyltransferase 5'-region. A unique housekeeping gene promoter.

1992 • 77 citations

Utilization of an alternative transcription initiation site of somatic cytochrome c in the mouse produces a testis-specific cytochrome c mRNA.

1993 • 52 citations

Isolation and Expression of a Chicken DNA Methyltransferase cDNA1

1995 • 33 citations

Expression in mammalian cells of a cloned gene encoding murine DNA methyltransferase

1991 • 26 citations

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