Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Molecular Evolutionary Genetics

1987 • 15,266 citations

Identification and expression cloning of a leptin receptor, OB-R

1995 • 3,498 citations

Protein modules and signalling networks

1995 • 2,447 citations

Abnormal splicing of the leptin receptor in diabetic mice

1996 • 2,361 citations

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1992 • 1,636 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

ENDOCYTOSIS AND MOLECULAR SORTING

1996 • 1,537 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

[47] Establishing homologies in protein sequences

1983 • 1,187 citations

The I.M.A.G.E. Consortium: An Integrated Molecular Analysis of Genomes and Their Expression

1996 • 1,132 citations

Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor

1997 • 907 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1993 • 658 citations

Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction

1996 • 629 citations

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

1987 • 479 citations

A role for leptin and its cognate receptor in hematopoiesis

1996 • 478 citations

Enhanced Degradation of EGF Receptors by a Sorting Nexin, SNX1

1996 • 379 citations

The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis.

1987 • 355 citations

Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3‐kinases: Binding partners of SH3 domains?

1996 • 304 citations

A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor.

1997 • 219 citations

Insulin-induced receptor loss in cultured human lymphocytes is due to accelerated receptor degradation.

1981 • 217 citations

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.

1996 • 213 citations

The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2.

1995 • 183 citations

Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors.

1993 • 155 citations

Antagonists of Phosphatidylinositol 3-Kinase Block Activation of Several Novel Protein Kinases in Neutrophils

1995 • 127 citations

The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi

1997 • 116 citations

Retrieval of Resident Late-Golgi Membrane Proteins from the Prevacuolar Compartment of Saccharomyces cerevisiae Is Dependent on the Function of Grd19p

1998 • 103 citations

The SH3-Domain Protein Bem1 Coordinates Mitogen-Activated Protein Kinase Cascade Activation with Cell Cycle Control in Saccharomyces cerevisiae

1996 • 97 citations

Involvement of dileucine motifs in the internalization and degradation of the insulin receptor

1994 • 90 citations

The Saccharomyces cerevisiae MVP1 Gene Interacts with VPS1 and Is Required for Vacuolar Protein Sorting

1995 • 77 citations

Receptor signalling and the regulation of endocytic membrane transport

1996 • 76 citations

Transfection of DNA into Isolated Rat Adipose Cells by Electroporation:

1993 • 76 citations

Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation.

1992 • 73 citations

Two steps of insulin receptor internalization depend on different domains of the beta-subunit [published erratum appears in J Cell Biol 1993 Nov;123(4):1047]

1993 • 67 citations

Streptavidin blotting: a sensitive technique to study cell surface proteins; application to investigate autophosphorylation and endocytosis of biotin-labeled insulin receptors.

1993 • 54 citations

The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases.

1993 • 50 citations

Inactivation of a sperm motility gene by insertion of an epidermal growth factor receptor transgene whose product is overexpressed and compartmentalized during spermatogenesis.

1991 • 46 citations

Effects of Overexpressing Wild-Type and Mutant PDGF Receptors on Translocation of GLUT4 in Transfected Rat Adipose Cells

1996 • 33 citations

Mechanisms of signal-mediated protein sorting in the endocytic and secretory pathways.

1996 • 33 citations

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