An RNA-Dependent RNA Polymerase Gene in Arabidopsis Is Required for Posttranscriptional Gene Silencing Mediated by a Transgene but Not by a Virus

Basic local alignment search tool

1990 • 87,358 citations

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1998 • 14,674 citations

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

2000 • 2,945 citations

RNAi

2000 • 2,596 citations

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans.

1990 • 2,386 citations

A procedure for mapping Arabidopsis mutations using co‐dominant ecotype‐specific PCR‐based markers

1993 • 1,574 citations

The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans

1999 • 1,286 citations

Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression.

1990 • 1,182 citations

Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA

1998 • 1,121 citations

Suppression of gene silencing: A general strategy used by diverse DNA and RNA viruses of plants

1999 • 1,038 citations

Initiation and Maintenance of Virus-Induced Gene Silencing

1998 • 972 citations

A Similarity Between Viral Defense and Gene Silencing in Plants

1997 • 821 citations

mut-7 of C. elegans, Required for Transposon Silencing and RNA Interference, Is a Homolog of Werner Syndrome Helicase and RNaseD

1999 • 745 citations

Induction of a Highly Specific Antiviral State in Transgenic Plants: Implications for Regulation of Gene Expression and Virus Resistance.

1993 • 734 citations

Systemic Spread of Sequence-Specific Transgene RNA Degradation in Plants Is Initiated by Localized Introduction of Ectopic Promoterless DNA

1998 • 694 citations

Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase

1999 • 653 citations

RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans

1998 • 561 citations

EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans

2000 • 546 citations

Transgene‐induced gene silencing in plants

1998 • 490 citations

RNA–DNA Interactions and DNA Methylation in Post-Transcriptional Gene Silencing

1999 • 452 citations

Gene Silencing without DNA: RNA-Mediated Cross-Protection between Viruses

1999 • 444 citations

The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized

1999 • 419 citations

Plants combat infection by gene silencing

1997 • 384 citations

Listening to the silent genes: transgene silencing, gene regulation and pathogen control

1999 • 367 citations

Isolation of quelling-defective ( qde ) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa

1997 • 307 citations

Posttranscriptional Gene Silencing in Neurospora by a RecQ DNA Helicase

1999 • 252 citations

Gene silencing in worms and fungi

2000 • 251 citations

Isolation of an RNA-Directed RNA Polymerase–Specific cDNA Clone from Tomato

1998 • 251 citations

Homology‐dependent resistance: transgenic virus resistance in plants related to homology‐dependent gene silencing

1995 • 243 citations

RNAi and double-strand RNA

1999 • 242 citations

Arabidopsis Mutants Impaired in Cosuppression

1998 • 238 citations

Potato Virus X Amplicons in Arabidopsis Mediate Genetic and Epigenetic Gene Silencing

2000 • 186 citations

Identification of plant genetic loci involved in a posttranscriptional mechanism for meiotically reversible transgene silencing.

1994 • 184 citations

Post‐transcriptional silencing of chalcone synthase in Petunia by inverted transgene repeats

1997 • 180 citations

RNA-directed RNA polymerase from tomato leaves. II. Catalytic in vitro properties

1993 • 152 citations

Position-Dependent Methylation and Transcriptional Silencing of Transgenes in Inverted T-DNA Repeats: Implications for Posttranscriptional Silencing of Homologous Host Genes in Plants

1998 • 143 citations

A transgene with repeated DNA causes high frequency, post‐transcriptional suppression of ACC‐oxidase gene expression in tomato

1998 • 132 citations

Transgenes are dispensable for the RNA degradation step of cosuppression

1998 • 120 citations

RNA-directed RNA polymerase from tomato leaves. I. Purification and physical properties

1993 • 107 citations

Gene silencing: RNA makes RNA makes no protein

1999 • 102 citations

Complete nucleotide sequence and genome organization of a tobamovirus infecting cruciferae plants

1994 • 71 citations

Infectious RNA Produced by in vitro Transcription of a Full-length Tobacco Rattle Virus RNA-1 cDNA

1989 • 50 citations

The Na+/H+ exchanger in immature and mature granulocytic HL-60 cells. Property changes induced by intracellular acidification and cell maturation.

1988 • 31 citations