Gene Silencing without DNA: RNA-Mediated Cross-Protection between Viruses

Assaying chimeric genes in plants: The GUS gene fusion system

1987 • 4,516 citations

Primary structure of the Aequorea victoria green-fluorescent protein

1992 • 2,135 citations

Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly

1997 • 1,321 citations

Improved Green Fluorescent Protein by Molecular Evolution Using DNA Shuffling

1996 • 1,212 citations

Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA

1998 • 1,121 citations

Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana

1998 • 1,073 citations

Initiation and Maintenance of Virus-Induced Gene Silencing

1998 • 972 citations

A viral suppressor of gene silencing in plants

1998 • 897 citations

A Similarity Between Viral Defense and Gene Silencing in Plants

1997 • 821 citations

A Counterdefensive Strategy of Plant Viruses

1998 • 815 citations

Induction of a Highly Specific Antiviral State in Transgenic Plants: Implications for Regulation of Gene Expression and Virus Resistance.

1993 • 734 citations

Systemic Spread of Sequence-Specific Transgene RNA Degradation in Plants Is Initiated by Localized Introduction of Ectopic Promoterless DNA

1998 • 694 citations

Cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA.

1995 • 678 citations

Plant viral synergism: the potyviral genome encodes a broad-range pathogenicity enhancer that transactivates replication of heterologous viruses.

1997 • 589 citations

Jellyfish green fluorescent protein as a reporter for virus infections

1995 • 504 citations

Potato virus X as a vector for gene expression in plants

1992 • 498 citations

Mechanisms of Pathogen-Derived Resistance to Viruses in Transgenic Plants.

1996 • 437 citations

Plants combat infection by gene silencing

1997 • 384 citations

Suppression of Virus Accumulation in Transgenic Plants Exhibiting Silencing of Nuclear Genes.

1996 • 375 citations

RNA-Mediated RNA Degradation and Chalcone Synthase A Silencing in Petunia

1997 • 308 citations

Transgenic plant virus resistance mediated by untranslatable sense RNAs: expression, regulation, and fate of nonessential RNAs.

1994 • 295 citations

RNA as a target and an initiator of post-transcriptional gene silencing in trangenic plants

1996 • 284 citations

Genome Amplification and Long-Distance Movement Functions Associated with the Central Domain of Tobacco Etch Potyvirus Helper Component–Proteinase

1997 • 247 citations

Homology‐dependent resistance: transgenic virus resistance in plants related to homology‐dependent gene silencing

1995 • 243 citations

Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA

1997 • 242 citations

Gene silencing from plant DNA carried by a Geminivirus

1998 • 234 citations

Transcriptional and Posttranscriptional Plant Gene Silencing in Response to a Pathogen

1998 • 217 citations

Systemic expression of a bacterial gene by a tobacco mosaic virus-based vector.

1991 • 209 citations

Genetic and biochemical dissection of transgenic RNA-mediated virus resistance.

1996 • 205 citations

Infection of Tobacco orArabidopsisPlants by CMV Counteracts Systemic Post-transcriptional Silencing of Nonviral (Trans)Genes

1998 • 178 citations

Cross protection among four viroids

1978 • 136 citations

Seed‐transmission of nematode‐borne viruses

1967 • 134 citations

Molecular analysis of a resistance-breaking strain of potato virus X

1992 • 127 citations

Does co-suppression of sense genes in transgenic plants involve antisense RNA?

1991 • 118 citations

Requirement of sense transcription for homology‐dependent virus resistance and trans‐inactivation

1997 • 118 citations

STUDIES ON THE PROPERTIES OF SOIL‐BORNE VIRUSES OF THE TOBACCO‐RATTLE TYPE OCCURRING IN SCOTLAND

1959 • 108 citations

Transgenic potato expressing a double-stranded RNA-specific ribonuclease is resistant to potato spindle tuber viroid

1997 • 98 citations

Delayed Resistance to Plum Pox Potyvirus Mediated by a Mutated RNA Replicase Gene: Involvement of a Gene-Silencing Mechanism

1997 • 90 citations

Tomato as a test plant for detecting mild strains of Potato spindle tuber virus.

1967 • 90 citations

A Transcriptionally Active State Is Required for Post-Transcriptional Silencing (Cosuppression) of Nitrate Reductase Host Genes and Transgenes.

1997 • 89 citations

The Tobraviruses

1978 • 82 citations

Testing the nuclear test-ban treaty

1997 • 68 citations

Post‐transcriptional silencing of chalcone synthase in petunia using a geminivirus‐based episomal vector

1998 • 65 citations

Virus-induced cell death in plants expressing the mammalian 2′,5′ oligoadenylate system

1996 • 62 citations

Alfalfa Mosaic Virus Transmission to Seed Through Alfalfa Gametes and Longevity in Alfalfa Seed

1974 • 59 citations

A mammalian 2-5A system functions as an antiviral pathway in transgenic plants.

1996 • 58 citations

Transmission of tobacco rattle virus isolate PpK20 by its nematode vector requires one of the two non-structural genes in the viral RNA 2.

1997 • 58 citations

Infectious RNA Produced by in vitro Transcription of a Full-length Tobacco Rattle Virus RNA-1 cDNA

1989 • 50 citations

Promoter-dependent trans-inactivation in transgenic tobacco plants : kinetic aspects of gene silencing and gene reactivation

1994 • 45 citations

Gene silencing and virus resistance: a common mechanism

1996 • 32 citations

Multiple small RNA species and the viroid hypothesis for the sunblotch disease of avocado

1980 • 25 citations

Replication of in vitro tobravirus recombinants shows that the specificity of template recognition is determined by 5' non-coding but not 3' non-coding sequences.

1997 • 22 citations

Efficient inoculation with CaMV 35 S promoter-driven DNA clones of the tobravirus PEBV

1992 • 20 citations