Transgenes are dispensable for the RNA degradation step of cosuppression

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans.

1990 • 2,386 citations

Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression.

1990 • 1,182 citations

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

1990 • 962 citations

A Similarity Between Viral Defense and Gene Silencing in Plants

1997 • 821 citations

Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions

1997 • 777 citations

Induction of a Highly Specific Antiviral State in Transgenic Plants: Implications for Regulation of Gene Expression and Virus Resistance.

1993 • 734 citations

Plants combat infection by gene silencing

1997 • 384 citations

Suppression of Virus Accumulation in Transgenic Plants Exhibiting Silencing of Nuclear Genes.

1996 • 375 citations

Suppression of beta-1,3-glucanase transgene expression in homozygous plants.

1992 • 303 citations

Transgene‐mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover

1994 • 297 citations

Transgenic plant virus resistance mediated by untranslatable sense RNAs: expression, regulation, and fate of nonessential RNAs.

1994 • 295 citations

Expression of single copies of a strongly expressed 35S transgene can be silenced post‐transcriptionally

1996 • 291 citations

Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation.

1994 • 284 citations

Induction of a Highly Specific Antiviral State in Transgenic Plants: Implications for Regulation of Gene Expression and Virus Resistance

1993 • 262 citations

Homology‐dependent resistance: transgenic virus resistance in plants related to homology‐dependent gene silencing

1995 • 243 citations

Genetic and biochemical dissection of transgenic RNA-mediated virus resistance.

1996 • 205 citations

The Frequency and Degree of Cosuppression by Sense Chalcone Synthase Transgenes Are Dependent on Transgene Promoter Strength and Are Reduced by Premature Nonsense Codons in the Transgene Coding Sequence.

1997 • 196 citations

RNA-Mediated Virus Resistance: Role of Repeated Transgenes and Delineation of Targeted Regions.

1996 • 196 citations

Identification of plant genetic loci involved in a posttranscriptional mechanism for meiotically reversible transgene silencing.

1994 • 184 citations

Post‐transcriptional silencing of chalcone synthase in Petunia by inverted transgene repeats

1997 • 180 citations

Plant Regeneration from Mesophyll Protoplasts of Several Nicotiana Species

1979 • 170 citations

Regulated inactivation of homologous gene expression in transgenic Nicotiana sylvestris plants containing a defense-related tobacco chitinase gene

1992 • 164 citations

Petal and stamen formation in petunia is regulated by the homeotic gene fbp1

1993 • 162 citations

Suppression of Virus Accumulation in Transgenic Plants Exhibiting Silencing of Nuclear Genes

1996 • 128 citations

Requirement of sense transcription for homology‐dependent virus resistance and trans‐inactivation

1997 • 118 citations

Post-transcriptional cosuppression of beta-1,3-glucanase genes does not affect accumulation of transgene nuclear mRNA.

1995 • 115 citations

Frequencies, Timing, and Spatial Patterns of Co-Suppression of Nitrate Reductase and Nitrite Reductase in Transgenic Tobacco Plants

1996 • 110 citations

Inhibition of tobacco nitrite reductase activity by expression of antisense RNA

1992 • 109 citations

Developmentally regulated silencing and reactivation of tobacco chitinase transgene expression

1996 • 109 citations

Co-suppression of nitrate reductase host genes and transgenes in transgenic tobacco plants

1994 • 107 citations

Nitrate Reductase mRNA Regulation in Nicotiana plumbaginifolia Nitrate Reductase-Deficient Mutants.

1989 • 103 citations

Requirement of sense transcription for homology‐dependent virus resistance and trans‐inactivation

1997 • 95 citations

A Transcriptionally Active State Is Required for Post-Transcriptional Silencing (Cosuppression) of Nitrate Reductase Host Genes and Transgenes.

1997 • 89 citations

Distinct features of post‐transcriptional gene silencing by antisense transgenes in single copy and inverted T‐DNA repeat loci

2000 • 89 citations

The Frequency and Degree of Cosuppression by Sense Chalcone Synthase Transgenes Are Dependent on Transgene Promoter Strength and Are Reduced by Premature Nonsense Codons in the Transgene Coding Sequence

1997 • 83 citations

Genetic analysis of nitrate reductase-deficient tobacco plants regenerated from mutant cells

1983 • 81 citations

Characterization of Post-Transcriptionally Suppressed Transgene Expression That Confers Resistance to Tobacco Etch Virus Infection in Tobacco.

1997 • 79 citations

Field trial analysis of nitrate reductase co-suppression: a comparative study of 38 combinations of transgene loci

1995 • 63 citations

RNA-Mediated Virus Resistance: Role of Repeated Transgenes and Delineation of Targeted Regions

1996 • 55 citations

Nitrate Reductase mRNA Regulation in Nicotiana plumbaginifolia Nitrate Reductase-Deficient Mutants

1989 • 25 citations

A Transcriptionally Active State Is Required for Post-Transcriptional Silencing (Cosuppression) of Nitrate Reductase Host Genes and Transgenes

1997 • 25 citations

Characterization of Post-Transcriptionally Suppressed Transgene Expression That Confers Resistance to Tobacco Etch Virus Infection in Tobacco

1997 • 23 citations