Evidence for the Presence of Insulin-Dependent Diabetes-Associated Alleles on the Distal Part of Mouse Chromosome 6

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Genetic variants and strains of the laboratory mouse

1990 • 1,519 citations

A genome-wide search for human type 1 diabetes susceptibility genes

1994 • 1,294 citations

Breeding of a Non-Obese, Diabetic Strain of Mice

1980 • 1,255 citations

Immunological Aspects of Demyelinating Diseases

1992 • 1,021 citations

A comprehensive genetic map of the mouse genome

1996 • 844 citations

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1995 • 749 citations

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

1984 • 744 citations

Genetic Analysis of Autoimmune Disease

1996 • 739 citations

Type-I Diabetes: A Chronic Autoimmune Disease of Human, Mouse, and Rat

1990 • 650 citations

A genetic map of the mouse with 4,006 simple sequence length polymorphisms

1994 • 543 citations

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

1991 • 494 citations

The NOD Mouse: Recessive Diabetogenic Gene in the Major Histocompatibility Complex

1986 • 424 citations

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.

1987 • 402 citations

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

1994 • 397 citations

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

1991 • 378 citations

Lessons from Animal Diabetes

1984 • 358 citations

Polygenic control of autoimmune diabetes in nonobese diabetic mice

1993 • 298 citations

Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR

1993 • 271 citations

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse.

1987 • 222 citations

Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide

1984 • 220 citations

Genetic dissection of autoimmune type I diabetes in the BB rat

1992 • 218 citations

Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes.

1992 • 178 citations

Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.

1991 • 160 citations

Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene.

1994 • 147 citations

Crosses of NOD Mice With the Related NON Strain: A Polygenic Model for IDDM

1995 • 140 citations

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

1997 • 129 citations

Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice

1991 • 129 citations

Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes.

1994 • 123 citations

Statistical evaluation of multiple-locus linkage data in experimental species and its relevance to human studies: application to nonobese diabetic (NOD) mouse and human insulin-dependent diabetes mellitus (IDDM).

1993 • 118 citations

Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27.

1995 • 115 citations

Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping.

1995 • 98 citations

Mutations in mice that influence natural killer (NK) cell activity

1981 • 95 citations

Evidence of a non-MHC susceptibility locus in type I diabetes linked to HLA on chromosome 6.

1997 • 93 citations

Death of a Beta Cell: Homicide or Suicide?

1986 • 92 citations

Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6.

1993 • 85 citations

Genetic and physiological association of diabetes susceptibility with raised Na+/H+ exchange activity.

1994 • 80 citations

Genetic analysis of diabetes and insulitis in an interspecific cross of the nonobese diabetic mouse with Mus spretus.

1993 • 60 citations

Type 1 Diabetes and the Control of Dexamethazone-Induced Apoptosis in Mice Maps to the Same Region on Chromosome 6

1995 • 55 citations

Multiple DNA variant association analysis: application to the insulin gene region in type I diabetes.

1994 • 54 citations

Chromosomal localization of an SH2-containing tyrosine phosphatase (PTPN6)

1992 • 52 citations

Autoimmune diabetes: the role of the islets of langerhans

1996 • 51 citations

A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6.

1995 • 43 citations

Mapping the diabetes polygene Idd3 on mouse Chromosome 3 by use of novel congenic strains

1995 • 41 citations

Molecular Cloning and Expression of the Type 1 and Type 2 Murine Receptors for Tumor Necrosis Factor

1991 • 36 citations

Mouse chromosome 6

1997 • 33 citations

Characterizations of candidate genes for IDD susceptibility from the diabetes-prone NOD mouse strain

1993 • 27 citations

Isolation and Regional Assignment of Human Chromosome 12p cDNAs

1995 • 23 citations

Genetics of insulin-dependent diabetes mellitus

1996 • 21 citations

Spontaneous production of colony-stimulating activity by splenic mac-1 antigen-positive cells from autoimmune motheaten mice

1984 • 19 citations

A candidate mouse model for Hartnup Disorder deficient in neutral amino acid transport

1997 • 19 citations

Spontaneous production of colony-stimulating activity by splenic Mac-1 antigen-positive cells from autoimmune motheaten mice.

1984 • 12 citations

Autoimmunity: Experimental Aspects

1994 • 12 citations

An anchored molecular map of mouse Chromosome 6 with an analysis of interference

1995 • 7 citations

[25]Selected methods related to the mouse as a model system

1996 • 2 citations

Type-I (insulin-dependent) and type-II (non-insulin-dependent) diabetes mellitus in BC1[(NODxMus spretus)F1xNOD] mice

1994 • 1 citations