Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse.

Breeding of a Non-Obese, Diabetic Strain of Mice

1980 • 1,255 citations

Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

1979 • 993 citations

MONOCLONAL ANTIBODIES TO MOUSE MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS

1982 • 471 citations

The histopathology of the pancreas in Type I (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom

1986 • 453 citations

The NOD Mouse: Recessive Diabetogenic Gene in the Major Histocompatibility Complex

1986 • 424 citations

The Spontaneously Diabetic Wistar Rat: Metabolic and Morphologic Studies

1977 • 409 citations

The Immune Response Genes of the Major Histocompatibility Complex

1978 • 382 citations

Transfer of Autoimmune Diabetes Mellitus with Splenocytes from Nonobese Diabetic (NOD) Mice

1986 • 371 citations

The Pathogenesis of Autoimmunity in New Zealand Black Mice

1974 • 264 citations

Genetic Complexity and Expression of Human Class II Histocompatibility Antigens

1985 • 247 citations

Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes.

1983 • 245 citations

Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide

1984 • 220 citations

Immunologic Aspects of the Nonobese Diabetic (NOD) Mouse: Abnormalities of Cellular Immunity

1983 • 199 citations

Specific genomic markers for the HLA-DQ subregion discriminate between DR4+ insulin-dependent diabetes mellitus and DR4+ seropositive juvenile rheumatoid arthritis.

1986 • 193 citations

Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain.

1979 • 192 citations

Spontaneous diabetes mellitus syndrome in the rat. I. Association with the major histocompatibility complex.

1981 • 155 citations

Passive Transfer of Diabetes in the BB/W Rat

1983 • 155 citations

The BB Diabetic Rat: Profound T-Cell Lymphocytopenia

1981 • 153 citations

A systematic study of HLA class II-beta DNA restriction fragments in insulin-dependent diabetes mellitus.

1985 • 134 citations

Effect of Castration on the Appearance of Diabetes in NOD Mouse

1981 • 116 citations

Adoptive transfer of autoimmune diabetes mellitus in biobreeding/Worcester (BB/W) inbred and hybrid rats.

1985 • 87 citations

Two genes required for diabetes in BB rats. Evidence from cyclical intercrosses and backcrosses.

1984 • 78 citations

Non-obese-diabetic mice: immune mechanisms of pancreatic ?-cell destruction

1984 • 76 citations

Diabetic BioBreeding/Worcester (BB/Wor) rats need not be lymphopenic.

1986 • 74 citations

Spontaneous Diabetes Mellitus in the BB/W Rat: Effects of Glucocorticoids, Cyclosporin-A, and Antiserum to Rat Lymphocytes

1983 • 68 citations

Small subunit of I–A subregion antigens determines the allospecificity recognized by a monoclonal antibody

1980 • 60 citations

Susceptibility to Insulin-dependent Diabetes Defined by Restriction Enzyme Polymorphism of HLA-D Region Genomic DNA

1984 • 46 citations

Immunological aspect of non-obese diabetic mice: immune islet cell-killing mechanism and cell-mediated immunity

1984 • 28 citations

A Particular Subset of HLA-DR4 Accounts for All or Most of the DR4 Association in Type I Diabetes

1985 • 23 citations

Animal model of human disease. Diabetes mellitus.

1980 • 23 citations

Sex-related immunocompetence of BALB/c mice. I. Study of immunologic responsiveness of neonatal, weanling, and young adult mice.

1979 • 22 citations

A minor subset of HLA-DR3 haplotypes is preferentially increased in Type 1 (insulin-dependent) diabetes

1985 • 21 citations

Selective reversal of H‐2‐linked genetic unresponsiveness to lysozymes: II. Alteration in the T helper/T suppressor balance, owing to gene(s) linked to Ir‐2, leads to responsiveness in BALB.B

1986 • 20 citations

Selective reversal of H-2 linked genetic unresponsiveness to lysozymes

1984 • 17 citations

Pancreatic cellular infiltrates in autoimmune-prone New Zealand Black mice

1984 • 11 citations