Overexpression of MDR-related p170 glycoprotein in chronic myeloid leukemia.

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1991 • 962 citations

Modulation of Activity of the Promoter of the Human MDR 1 Gene by Ras and p53

1992 • 735 citations

Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy.

1989 • 565 citations

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

1986 • 561 citations

Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosis [see comments]

1992 • 507 citations

MDR1 Gene Expression and Treatment Outcome in Acute Myeloid Leukemia

1991 • 372 citations

Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments]

1992 • 347 citations

Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistant phenotype [see comments]

1992 • 323 citations

Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments]

1992 • 290 citations

Staging and prognosis in chronic myelogenous leukemia.

1988 • 221 citations

Multidrug resistance (mdr) genes in human cancer

1991 • 209 citations

MDR₁ transcript levels as an indication of resistant disease in acute myelogenous leukaemia

1990 • 184 citations

P-glycoproteins in pathology: The multidrug resistance gene family in humans

1990 • 173 citations

Expression of the multidrug resistance gene in myeloid leukemias

1990 • 124 citations

Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistant phenotype [see comments]

1992 • 110 citations

Immunohistochemical detection of the multidrug transport protein P1 70 in human normal tissues and malignant lymphomas

1991 • 104 citations

Relevance of mdr1 gene expression in acute myeloid leukemia and comparison of different diagnostic methods.

1992 • 101 citations

The multidrug resistance phenotype

1988 • 92 citations

Expression of the multidrug transporter, P‐glycoprotein, in chronic myelogenous leukaemia cells in blast crisis

1990 • 92 citations

Clonal Origin of Chronic Myelocytic Leukemia

1973 • 76 citations

Detection of multidrug resistance markers, P-glycoprotein and mdr1 mRNA, in human leukemia cells.

1987 • 72 citations

Overexpression of multidrug resistance‐associated p170‐glycoprotein in acute non‐lymphocytic leukemia

1992 • 70 citations

Expression of multidrug resistance gene (MDR-1) in human normal leukocytes.

1993 • 35 citations

The role of the MDR-1/P-170 mechanism in the development of multidrug resistance in chronic myeloid leukemia.

1990 • 27 citations

mdr‐1 GENE AMPLIFICATION IN ACUTE LYMPHOBLASTIC LEUKAEMIA PRIOR TO ANTILEUKAEMIC TREATMENT

1991 • 24 citations

p170-dependent multidrug resistance. Restoring full sensitivity to idarubicin with verapamil and cyclosporin A derivatives.

1994 • 21 citations

Chronic Myeloid Leukemia

2006 • 21 citations

D-Verapamil downmodulates P170-associated resistance to doxorubicin, daunorubicin and idarubicin

1993 • 19 citations

P-glycoprotein and drug resistance in acute leukemias and in the blastic crisis of chronic myeloid leukemia.

1990 • 16 citations

Multidrug Resistance (MDR) Gene Expression in Acute Non Lymphoblastic Leukemia: Sequential Analysis

1992 • 15 citations

Multidrug resistance: focus in hematology.

1990 • 13 citations

Expression of multidrug resistance gene (MDR1) in normal hematopoietic cells [letter; comment]

1993 • 7 citations

Cancer chemotherapy does not enhance MDR-associated 170 kd glycoprotein expression in normal blood mononuclear cells.

1992 • 5 citations