Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes

Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation

2002 • 1,516 citations

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

1997 • 1,221 citations

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

1994 • 930 citations

Ubiquitination of a Yeast Plasma Membrane Receptor Signals Its Ligand-Stimulated Endocytosis

1996 • 789 citations

Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

2003 • 767 citations

Back to the Future with Ubiquitin

2004 • 676 citations

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1998 • 676 citations

Nuclear and unclear functions of SUMO

2003 • 651 citations

SUMO-1 modification activates the transcriptional response of p53

1999 • 627 citations

Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

1984 • 522 citations

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex.

1992 • 497 citations

Identification of two lysosomal membrane glycoproteins.

1985 • 475 citations

The F-Box Protein Skp2 Participates in c-Myc Proteosomal Degradation and Acts as a Cofactor for c-Myc-Regulated Transcription

2003 • 466 citations

Reduced Ubiquitin-Dependent Degradation of c-Jun After Phosphorylation by MAP Kinases

1997 • 462 citations

Mammalian Tumor Susceptibility Gene 101 (TSG101) and the Yeast Homologue, Vps23p, Both Function in Late Endosomal Trafficking

2000 • 401 citations

Emerging Roles of Ubiquitin in Transcription Regulation

2002 • 395 citations

Regulation of p53 activity in nuclear bodies by a specific PML isoform

2000 • 371 citations

A superfamily of protein tags: ubiquitin, SUMO and related modifiers

2003 • 367 citations

Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase

2004 • 367 citations

SUMO-1 Modification Represses Sp3 Transcriptional Activation and Modulates Its Subnuclear Localization

2002 • 365 citations

Regulation of Transcriptional Activation Domain Function by Ubiquitin

2001 • 363 citations

The Ubiquitin Ligase SCF ^Fbw7 Antagonizes Apoptotic JNK Signaling

2004 • 345 citations

The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins.

1990 • 327 citations

Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation

2002 • 326 citations

Regulation of Transcription by Ubiquitination without Proteolysis

2000 • 292 citations

Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins.

1987 • 197 citations

Cloning of a cDNA Which Encodes a Novel Ubiquitin-like Protein

1993 • 146 citations

Fortuitous convergences: the beginnings of JUN

2002 • 139 citations

The HECT Domain Ligase Itch Ubiquitinates Endophilin and Localizes to the trans-Golgi Network and Endosomal System

2004 • 114 citations

A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK

2000 • 84 citations

Chromatin conjugate protein A24 is cleaved and ubiquitin is lost during chicken erythropoiesis.

1980 • 72 citations

ATP-stimulated proteolysis in soluble extracts of BHK 21C13 cells

1988 • 60 citations