Neutralizing antibodies to IFN-gamma-inducing factor prevent experimental autoimmune encephalomyelitis.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (57)
Antibodies, a laboratory manual
1989 • 12,929 citations
TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties
1989 • 7,558 citations
Functional diversity of helper T lymphocytes
1996 • 4,512 citations
Cloning of a new cytokine that induces IFN-γ production by T cells
1995 • 2,584 citations
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.
1991 • 1,880 citations
Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin
1992 • 1,711 citations
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
1995 • 1,695 citations
Progress in Clinical and Biological Research
1979 • 1,317 citations
IL-4 directs the development of Th2-like helper effectors.
1990 • 1,261 citations
Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production
1997 • 1,172 citations
Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme
1997 • 1,137 citations
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
1995 • 1,120 citations
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.
1992 • 1,029 citations
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.
1993 • 991 citations
The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis
1981 • 917 citations
Interleukin-12 and its role in the generation of TH1 cells
1993 • 869 citations
Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.
1993 • 837 citations
IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB
1997 • 726 citations
An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis.
1990 • 692 citations
Interferon‐γ‐inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin‐12 for interferon‐γ production
1996 • 606 citations
T Helper Cell Subsets in Insulin-Dependent Diabetes
1995 • 600 citations
Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease.
1994 • 599 citations
Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.
1995 • 560 citations
IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12.
1997 • 528 citations
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.
1993 • 510 citations
Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro.
1996 • 493 citations
Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients.
1996 • 487 citations
An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease
1998 • 479 citations
Interferon‐γ confers resistance to experimental allergic encephalomyelitis
1996 • 478 citations
Anti—tumor necrosis factor therapy abrogates autoimmune demyelination
1991 • 434 citations
Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma.
1988 • 432 citations
Requirement for CD40 Ligand in Costimulation Induction, T Cell Activation, and Experimental Allergic Encephalomyelitis
1996 • 425 citations
Multiple Sclerosis
1982 • 415 citations
Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis
1993 • 400 citations
Tumor necrosis factor combines with IL-4 or IFN-gamma to selectively enhance endothelial cell adhesiveness for T cells. The contribution of vascular cell adhesion molecule-1-dependent and -independent binding mechanisms.
1991 • 398 citations
Role of cytokines in determining T-lymphocyte function
1994 • 396 citations
Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
1989 • 390 citations
Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein
1996 • 389 citations
Interleukin‐10 prevents experimental allergic encephalomyelitis in rats
1994 • 377 citations
Experimental Allergic Encephalomyelitis. A Useful Model for Multiple Sclerosis
1984 • 340 citations
A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma.
1997 • 325 citations
Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity
1990 • 285 citations
Suppressive vaccination with DNA encoding a variable region gene of the T–cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity
1996 • 244 citations
Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production.
1994 • 216 citations
TH2 activated cells prevent experimental autoimmune uveoretinitis, a TH1‐dependent autoimmune disease
1993 • 182 citations
Cytokine transcriptional events during helper T cell subset differentiation.
1996 • 174 citations
Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2.
1997 • 165 citations
Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells.
1995 • 150 citations
Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon‐γ
1996 • 141 citations
In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice.
1995 • 141 citations
Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats.
1994 • 135 citations
Human tumor necrosis factor-α augments experimental allergic encephalomyelitis in rats
1991 • 130 citations
Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells.
1995 • 127 citations
Multiple sclerosis: a pivotal role for the T cell in lesion development
1991 • 118 citations
IL-4 and IL-13 production in differentiated T helper type 2 cells is not IL-4 dependent.
1997 • 87 citations
Selective and nonselective stages in homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis.
1993 • 87 citations
Systemic Production of Interferon-Gamma Inducing Factor (IGIF) Versus Local IFN-γ Expression Involved in the Development of Th1 Insulitis in NOD Mice
1997 • 53 citations
Cited By (0)
No citing papers found in database