Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

IL-10 inhibits cytokine production by activated macrophages.

1991 • 2,919 citations

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

1992 • 1,200 citations

The adhesion molecule and cytokine profile of multiple sclerosis lesions

1995 • 761 citations

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease.

1994 • 599 citations

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.

1990 • 548 citations

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

1992 • 501 citations

Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis

1993 • 400 citations

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones.

1994 • 323 citations

A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis.

1991 • 286 citations

Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity

1990 • 285 citations

Induction of relapsing paralysis in experimental autoimmune encephalomyelitis by bacterial superantigen

1993 • 260 citations

T cell recognition as the target for immune intervention in autoimmune disease

1989 • 218 citations

Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production.

1994 • 216 citations

Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides.

1994 • 179 citations

Analysis of cytokine mRNA levels in interleukin‐4‐transgenic mice by quantitative polymerase chain reaction

1992 • 139 citations

Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor CαCδ region

1992 • 134 citations

Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. II. Biased T cell receptor V beta expression predominates in spinal cord infiltrating T cells.

1992 • 94 citations

Multiple sclerosis: TNF revisited, with promise

1995 • 88 citations

Diverse T cell receptor V beta gene usage in the central nervous system in experimental allergic encephalomyelitis.

1993 • 62 citations