Genomic Characterization of LIGHT Reveals Linkage to an Immune Response Locus on Chromosome 19p13.3 and Distinct Isoforms Generated by Alternate Splicing or Proteolysis

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

TRANSFAC: an integrated system for gene expression regulation

2000 • 1,236 citations

Herpes Simplex Virus-1 Entry into Cells Mediated by a Novel Member of the TNF/NGF Receptor Family

1996 • 1,068 citations

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

1998 • 789 citations

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1998 • 781 citations

LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

1998 • 760 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

1999 • 636 citations

The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.

1989 • 511 citations

Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

1993 • 468 citations

The Structure of Tumor Necrosis Factor-α at 2.6 Å Resolution

1989 • 441 citations

LIGHT, a TNF-Like Molecule, Costimulates T Cell Proliferation and Is Required for Dendritic Cell-Mediated Allogeneic T Cell Response

2000 • 394 citations

A Newly Identified Member of Tumor Necrosis Factor Receptor Superfamily (TR6) Suppresses LIGHT-mediated Apoptosis

1999 • 370 citations

Inhibition of dendritic cell maturation by herpes simplex virus

1999 • 369 citations

Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway

2000 • 309 citations

Mature Dendritic Cells Infected with Herpes Simplex Virus Type 1 Exhibit Inhibited T-Cell Stimulatory Capacity

2000 • 287 citations

LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer.

1998 • 277 citations

Herpesvirus Entry Mediator Ligand (HVEM-L), a Novel Ligand for HVEM/TR2, Stimulates Proliferation of T Cells and Inhibits HT29 Cell Growth

1998 • 241 citations

Molecular mapping of the human major histocompatibility complex by pulsed-field gel electrophoresis.

1987 • 237 citations

A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.

1995 • 234 citations

The Lymphotoxin-β Receptor Is Necessary and Sufficient for LIGHT-mediated Apoptosis of Tumor Cells

2000 • 223 citations

Structure of the human interleukin 2 gene.

1983 • 197 citations

Cutting Edge: A Novel Viral TNF Receptor Superfamily Member in Virulent Strains of Human Cytomegalovirus

1999 • 179 citations

Reciprocal Expression of the TNF Family Receptor Herpes Virus Entry Mediator and Its Ligand LIGHT on Activated T Cells: LIGHT Down-Regulates Its Own Receptor

2000 • 176 citations

Herpes Simplex Virus Type 1 Infection of Activated Cytotoxic T Cells

1999 • 114 citations

The chromosomal duplication model of the major histocompatibility complex

1999 • 105 citations

Lymphotoxins and Cytomegalovirus Cooperatively Induce Interferon-β, Establishing Host-Virus Détente

2001 • 96 citations

Membrane Lymphotoxin Is Required for the Development of Different Subpopulations of NK T Cells

2000 • 67 citations

The MHC Big Bang

1999 • 67 citations

Virtual reality in the MHC

1999 • 57 citations

Production of lymphotoxin (LTα) and a soluble dimeric form of its receptor using the baculovirus expression system

1994 • 45 citations

Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first.

1994 • 39 citations

Expression of Lymphotoxins and Their Receptor–Fc Fusion Proteins by Baculovirus

2000 • 24 citations

Improving the copy numbers of antibody fragments expressed on the major coat protein of bacteriophage M13

1996 • 10 citations

Human T cell hybridomas producing cytotoxic lymphokines: induction of lymphotoxin release and killer cell activity by anti-CD3 monoclonal antibody or lectins and phorbol ester.

1986 • 9 citations