Herpes Simplex Virus Type 1 Infection of Activated Cytotoxic T Cells

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 • 1,662 citations

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

1995 • 1,549 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1997 • 1,305 citations

Herpes Simplex Viruses

1998 • 1,147 citations

Herpes Simplex Virus-1 Entry into Cells Mediated by a Novel Member of the TNF/NGF Receptor Family

1996 • 1,068 citations

Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off

1998 • 989 citations

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 • 983 citations

LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

1998 • 760 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

1994 • 553 citations

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction

1991 • 523 citations

Activation interferes with the APO-1 pathway in mature human T cells

1993 • 466 citations

Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals.

1995 • 438 citations

How do cytotoxic lymphocytes kill their targets?

1998 • 398 citations

Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

1999 • 385 citations

I-FLICE, a Novel Inhibitor of Tumor Necrosis Factor Receptor-1- and CD-95-induced Apoptosis

1997 • 372 citations

The Roles of Costimulation and Fas in T Cell Apoptosis and Peripheral Tolerance

1996 • 367 citations

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

1996 • 350 citations

A Novel Family of Viral Death Effector Domain-containing Molecules That Inhibit Both CD-95- and Tumor Necrosis Factor Receptor-1-induced Apoptosis

1997 • 343 citations

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.

1992 • 342 citations

FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis

1997 • 339 citations

CASH, a Novel Caspase Homologue with Death Effector Domains

1997 • 323 citations

Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP.

1996 • 271 citations

The herpes simplex virus 1 protein kinase U _S 3 is required for protection from apoptosis induced by the virus

1997 • 271 citations

Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner

1998 • 245 citations

Induction of Fas Ligand Expression by HIV Involves the Interaction of Nef with the T Cell Receptor ζ Chain

1999 • 242 citations

Infected Cell Protein (ICP)47 Enhances Herpes Simplex Virus Neurovirulence by Blocking the CD8+ T Cell Response

1998 • 188 citations

High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children [letter]

1994 • 174 citations

Resistance of cultured peripheral T cells towards activation‐induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death‐inducing signaling complex

1997 • 172 citations

In vivo analysis of Fas/FasL interactions in HIV-infected patients.

1998 • 153 citations

Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells

1997 • 128 citations

HLA class I molecules are not transported to the cell surface in cells infected with herpes simplex virus types 1 and 2.

1994 • 126 citations

Herpes Simplex Virus Type 1 Renders Infected Cells Resistant to Cytotoxic T-Lymphocyte-Induced Apoptosis

1998 • 112 citations

In vivo responses of CD4⁺ and CD8⁺ cells to bacterial superantigens

1992 • 109 citations

VIRAL LEUKOCYTE INTERRELATIONSHIPS. I. MULTIPLICATION OF A DNA VIRUS--HERPES SIMPLEX--IN HUMAN LEUKOCYTE CULTURES.

1964 • 91 citations

Resistance of cloned cytotoxic T lymphocytes to cell-mediated cytotoxicity.

1987 • 89 citations

Induction and Measurement of Cytotoxic T Lymphocyte Activity

2018 • 85 citations

Expression of the fas antigen in patients infected with human immunodeficiency virus

1995 • 85 citations

The Regulation of CD95 Ligand Expression and Function in CTL

1998 • 73 citations

Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules.

1987 • 71 citations

Cognate peptide-induced destruction of CD8+ cytotoxic T lymphocytes is due to fratricide.

1993 • 68 citations

Activation of Human T Cells with Superantigen (Staphylococcal Enterotoxin B) and CD28 Confers Resistance to Apoptosis via CD95

1998 • 64 citations

Differential TCR Signaling Regulates Apoptosis and Immunopathology during Antigen Responses In Vivo

1998 • 63 citations

Maintenance of clonotype specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes.

1997 • 62 citations

Monoclonal antibodies against an H-2Kb-specific cytotoxic T cell clone detect several clone-specific molecules.

1986 • 61 citations

Interactions between MHC-encoded products and cloned T-cells. I. Fine specificity of induction of proliferation and lysis

1982 • 55 citations

Antigen‐specific CD8⁺ T cell subset distribution in lymph nodes draining the site of herpes simplex virus infection

1997 • 48 citations

Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perforin.

1994 • 45 citations

Paralysis of B7 co-stimulation through the effect of viral IL-10 on T cells as a mechanism of local tolerance induction

1998 • 42 citations

The most efficient cytotoxic T lymphocytes are the least susceptible to lysis.

1987 • 41 citations

Viral Leukocyte Interrelationships

1964 • 40 citations

Herpesviruses and Immunity

2002 • 37 citations

Replication of Herpes Simplex Virus in Human Peripheral T Lymphocytes

1977 • 35 citations

Infection and inhibition of human cytotoxic T lymphocytes by herpes simplex virus

1994 • 22 citations

Immunopathology of Herpesvirus Infections

1985 • 21 citations

Interaction between MHC-encoded products and cloned T cells

1984 • 14 citations