The Lymphotoxin-β Receptor Is Necessary and Sufficient for LIGHT-mediated Apoptosis of Tumor Cells

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

1997 • 10,943 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1995 • 1,311 citations

TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS

1999 • 1,309 citations

Herpes Simplex Virus-1 Entry into Cells Mediated by a Novel Member of the TNF/NGF Receptor Family

1996 • 1,068 citations

TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40

1995 • 1,046 citations

The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

1999 • 922 citations

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

1993 • 857 citations

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1998 • 781 citations

LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

1998 • 760 citations

The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues

1998 • 710 citations

TRAIL Receptors 1 (DR4) and 2 (DR5) Signal FADD-Dependent Apoptosis and Activate NF-κB

1997 • 683 citations

DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

1999 • 636 citations

Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death

1998 • 597 citations

Distinct Roles in Lymphoid Organogenesis for Lymphotoxins α and β Revealed in Lymphotoxin β–Deficient Mice

1997 • 590 citations

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

1993 • 541 citations

Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

1993 • 468 citations

Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness.

1995 • 436 citations

Role of Lymphotoxin and the Type I TNF Receptor in the Formation of Germinal Centers

1996 • 386 citations

A Newly Identified Member of Tumor Necrosis Factor Receptor Superfamily (TR6) Suppresses LIGHT-mediated Apoptosis

1999 • 370 citations

Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice

1997 • 365 citations

TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor

1996 • 343 citations

Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

1993 • 341 citations

Herpesvirus Entry Mediator, a Member of the Tumor Necrosis Factor Receptor (TNFR) Family, Interacts with Members of the TNFR-associated Factor Family and Activates the Transcription Factors NF-κB and AP-1

1997 • 294 citations

Induction of cell death by tumour necrosis factor (TNF) receptor 2,CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF

1999 • 286 citations

LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer.

1998 • 277 citations

Herpesvirus Entry Mediator Ligand (HVEM-L), a Novel Ligand for HVEM/TR2, Stimulates Proliferation of T Cells and Inhibits HT29 Cell Growth

1998 • 241 citations

Lymphotoxin-α (LTα) Supports Development of Splenic Follicular Structure That Is Required for IgG Responses

1997 • 193 citations

Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor.

1996 • 181 citations

ATAR, a Novel Tumor Necrosis Factor Receptor Family Member, Signals through TRAF2 and TRAF5

1997 • 176 citations

Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB

1997 • 168 citations

T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors.

1996 • 165 citations

Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines.

1996 • 153 citations

Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors.

1995 • 146 citations

Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-β receptor–IgG1 fusion protein

1996 • 125 citations

Expression of the lymphotoxin β receptor on follicular stromal cells in human lymphoid tissues

1998 • 107 citations

Dominant Negative Mutants of TRAF3 Reveal an Important Role for the Coiled Coil Domains in Cell Death Signaling by the Lymphotoxin-β Receptor

1997 • 83 citations

Activation of the lymphotoxin beta receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells.

1997 • 78 citations

Discrete Signaling Regions in the Lymphotoxin-β Receptor for Tumor Necrosis Factor Receptor-associated Factor Binding, Subcellular Localization, and Activation of Cell Death and NF-κB Pathways

2000 • 59 citations

TNF receptor signal transduction. Ligand-dependent stimulation of a serine protein kinase activity associated with (CD120a) TNFR60.

1994 • 48 citations

Production of lymphotoxin (LTα) and a soluble dimeric form of its receptor using the baculovirus expression system

1994 • 45 citations

Aspartic acid 50 and tyrosine 108 are essential for receptor binding and cytotoxic activity of tumour necrosis factor beta (lymphotoxin)

1991 • 45 citations

The Cytoplasmic Domain of the Lymphotoxin-β Receptor Mediates Cell Death in HeLa Cells

1999 • 43 citations

Preparation and Characterization of Soluble Recombinant Heterotrimeric Complexes of Human Lymphotoxins and

1996 • 41 citations

Structural and functional domains in human tumour necrosis factors

1991 • 37 citations

The Lymphotoxin-α (LTα) Subunit Is Essential for the Assembly, but Not for the Receptor Specificity, of the Membrane-anchored LTα1β2 Heterotrimeric Ligand

1997 • 34 citations

Expression of Lymphotoxins and Their Receptor–Fc Fusion Proteins by Baculovirus

2000 • 24 citations