Two CD95 tumor classes with different sensitivities to antitumor drugs

Two CD95 (APO-1/Fas) signaling pathways

1998 • 3,045 citations

Systematic variation in gene expression patterns in human cancer cell lines

2000 • 2,119 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL

1997 • 1,119 citations

The CD95(APO-1/Fas) DISC and beyond

2003 • 1,064 citations

Phosphatidylinositol 3-Kinase Function Is Required for Transforming Growth Factor β-mediated Epithelial to Mesenchymal Transition and Cell Migration

2000 • 956 citations

Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

1989 • 943 citations

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

1998 • 789 citations

Downregulation of Fas ligand by shedding

1998 • 681 citations

FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive Streak

2001 • 675 citations

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1995 • 656 citations

Differential Modulation of Apoptosis Sensitivity in CD95 Type I and Type II Cells

1999 • 595 citations

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

1998 • 531 citations

Induction and regulation of epithelial–mesenchymal transitions

2000 • 434 citations

The CD95 Type I/Type II model

2003 • 415 citations

Molecular Ordering of the Initial Signaling Events of CD95

2002 • 387 citations

Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens.

1992 • 282 citations

FADD is required for multiple signaling events downstream of the receptor Fas.

1999 • 179 citations

Phosphorylation on Tyrosine-15 of p34Cdc2 by ErbB2 Inhibits p34Cdc2 Activation and Is Involved in Resistance to Taxol-Induced Apoptosis

2002 • 133 citations

Morphological and immunocytochemical characteristics of human tumor cell lines for use in a disease-oriented anticancer drug screen.

1992 • 119 citations

Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1)

2002 • 96 citations

Extracellular matrix interacts with soluble CD95L: Retention and enhancement of cytotoxicity

2001 • 91 citations

APO-1(CD95)-dependent and -independent antigen receptor-induced apoptosis in human T and B cell lines

1995 • 68 citations

Actin dependent CD95 internalization is specific for Type I cells

2003 • 48 citations

The two CD95 apoptosis signaling pathways may be a way of cells to respond to different amounts and/or forms of CD95 ligand produced in different tissues

2000 • 12 citations