Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

Bone Resorption by Osteoclasts

2000 • 3,797 citations

Wnt signaling and cancer

2000 • 3,215 citations

Control of apoptosis and mitotic spindle checkpoint by survivin

1998 • 1,881 citations

Plasma cell differentiation requires the transcription factor XBP-1

2001 • 1,256 citations

Humoral Immunity Due to Long-Lived Plasma Cells

1998 • 1,223 citations

Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

2001 • 1,110 citations

Lymphocyte-Mediated Cytotoxicity

2002 • 1,079 citations

Blimp-1 Orchestrates Plasma Cell Differentiation by Extinguishing the Mature B Cell Gene Expression Program

2002 • 1,000 citations

Gene Expression Profiling of B Cell Chronic Lymphocytic Leukemia Reveals a Homogeneous Phenotype Related to Memory B Cells

2001 • 934 citations

Tolerization of dendritic cells by TS cells: the crucial role of inhibitory receptors ILT3 and ILT4

2002 • 800 citations

Dual specificity phosphatases: a gene family for control of MAP kinase function

2000 • 791 citations

PRINCIPAL COMPONENTS ANALYSIS TO SUMMARIZE MICROARRAY EXPERIMENTS: APPLICATION TO SPORULATION TIME SERIES

1999 • 764 citations

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1994 • 752 citations

Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells

2002 • 655 citations

Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

2000 • 606 citations

Frzb, a Secreted Protein Expressed in the Spemann Organizer, Binds and Inhibits Wnt-8

1997 • 508 citations

Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells

1996 • 495 citations

Blimp-1-Dependent Repression of Pax-5 Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells

2002 • 427 citations

A Novel Inhibitory Receptor (ILT3) Expressed on Monocytes, Macrophages, and Dendritic Cells Involved in Antigen Processing

1997 • 426 citations

Chemotactic Responsiveness Toward Ligands for CXCR3 and CXCR4 Is Regulated on Plasma Blasts During the Time Course of a Memory Immune Response

2002 • 352 citations

Midkine Binds to Anaplastic Lymphoma Kinase (ALK) and Acts as a Growth Factor for Different Cell Types

2002 • 349 citations

Commitment of B Lymphocytes to a Plasma Cell Fate Is Associated with Blimp-1 Expression In Vivo

2000 • 337 citations

Role of Members of the Wnt Gene Family in Human Hematopoiesis

1998 • 333 citations

Intrinsic Constraint on Plasmablast Growth and Extrinsic Limits of Plasma Cell Survival

2000 • 311 citations

Plasma cells: finding new light at the end of B cell development

2001 • 305 citations

The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression

2002 • 281 citations

Stromal cell–derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G0/G1 transition in CD34+ cells: evidence for an autocrine/paracrine mechanism

2002 • 276 citations

Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma

2002 • 275 citations

Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts

2003 • 270 citations

Pax5/BSAP Maintains the Identity of B Cells in Late B Lymphopoiesis

2001 • 246 citations

Subtractive hybridization reveals the expression of immunoglobulinlike transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells

2002 • 243 citations

Proteinases in bone resorption: obvious and less obvious roles

2000 • 222 citations

BLIMP-1 mediates extinction of major histocompatibility class II transactivator expression in plasma cells

2000 • 213 citations

Generation of Plasma Cells From Peripheral Blood Memory B Cells: Synergistic Effect of Interleukin-10 and CD27/CD70 Interaction

1998 • 204 citations

Insulin-like growth factor I is a growth and survival factor in human multiple myeloma cell lines

1996 • 190 citations

A molecular compendium of genes expressed in multiple myeloma

2002 • 186 citations

Metalloproteinases in Multiple Myeloma: Production of Matrix Metalloproteinase-9 (MMP-9), Activation of proMMP-2, and Induction of MMP-1 by Myeloma Cells

1997 • 186 citations

Interleukin-6 is a growth factor for nonmalignant human plasmablasts

2001 • 181 citations

3pK, a Novel Mitogen-Activated Protein (MAP) Kinase-Activated Protein Kinase, Is Targeted by Three MAP Kinase Pathways

1996 • 180 citations

Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays

2002 • 172 citations

Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development

2003 • 170 citations

Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-β

2001 • 166 citations

Reactive Plasmacytoses Are Expansions of Plasmablasts Retaining the Capacity to Differentiate Into Plasma Cells

1999 • 157 citations

Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts

2002 • 156 citations

Short-lived and Long-lived Bone Marrow Plasma Cells Are Derived from a Novel Precursor Population

2002 • 155 citations

Insulin-like growth factor induces the survival and proliferation of myeloma cells through an interleukin-6-independent transduction pathway

2000 • 154 citations

Protein-Protein and DNA-Protein Interactions Affect the Activity of Lymphoid-Specific IFN Regulatory Factors

1999 • 135 citations

Homozygous Deletion in the Coding Sequence of the c-mer Gene in RCS Rats Unravels General Mechanisms of Physiological Cell Adhesion and Apoptosis

2000 • 135 citations

Regulation of CD27 expression in the course of germinal center B cell differentiation: the pivotal role of IL-10

2000 • 129 citations

Expression of functional interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma

2000 • 129 citations

Reactive Plasmacytoses Are Expansions of Plasmablasts Retaining the Capacity to Differentiate Into Plasma Cells

1999 • 122 citations

Repression of c-mycIs Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro

2000 • 100 citations

Identification of Human Asparaginyl Endopeptidase (Legumain) as an Inhibitor of Osteoclast Formation and Bone Resorption

1999 • 99 citations

Biological Effects of c-Mer Receptor Tyrosine Kinase in Hematopoietic Cells Depend on the Grb2 Binding Site in the Receptor and Activation of NF-κB

1999 • 97 citations

Cutting Edge: Polycomb Gene Expression Patterns Reflect Distinct B Cell Differentiation Stages in Human Germinal Centers

2000 • 94 citations

EB/RP gene family encodes tubulin binding proteins

1999 • 82 citations

Mechanism of Stimulation of Osteoclastic Bone Resorption through Gas6/Tyro 3, a Receptor Tyrosine Kinase Signaling, in Mouse Osteoclasts

2001 • 81 citations

The main biological determinants of tumor line taxonomy elucidated by a principal component analysis of microarray data

2001 • 68 citations

Review: The Role of IRF-4 in B and T Cell Activation and Differentiation

2002 • 60 citations

Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy

1999 • 56 citations

Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells.

2002 • 54 citations

Silencing of B Cell Receptor Signals in Human Naive B Cells

2002 • 53 citations

Regulation of Cytokine Signaling by B Cell Antigen Receptor and Cd40-Controlled Expression of Heparan Sulfate Proteoglycans

2000 • 50 citations

Consistent loss of functional transforming growth factor β receptor expression in murine plasmacytomas

1998 • 43 citations

Structure, chromosome mapping, and expression of the mouse Lyl-1 gene.

1991 • 41 citations

Expression of CD40 and CD43 during Activation of Human B Lymphocytes

1991 • 34 citations

A peptidyl derivative structurally based on the inhibitory center of cystatin C inhibits bone resorption in vitro

2000 • 32 citations

Distinct Roles of Cathepsin K and Cathepsin L IN Osteoclastic Bone Resorption

2000 • 27 citations