Control of apoptosis and mitotic spindle checkpoint by survivin

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Double identity for proteins of the Bcl-2 family

1997 • 1,511 citations

Mutations of mitotic checkpoint genes in human cancers

1998 • 1,482 citations

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1997 • 1,316 citations

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

1998 • 1,243 citations

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 • 1,027 citations

A p53-Dependent Mouse Spindle Checkpoint

1995 • 668 citations

Tau protein binds to microtubules through a flexible array of distributed weak sites.

1991 • 540 citations

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

1996 • 515 citations

Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.

1998 • 512 citations

Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.

1998 • 473 citations

PURIFICATION OF TUBULIN AND ASSOCIATED HIGH MOLECULAR WEIGHT PROTEINS FROM PORCINE BRAIN AND CHARACTERIZATION OF MICROTUBULE ASSEMBLY IN VITRO*

1975 • 423 citations

Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting

1998 • 413 citations

Microtubule organization and dynamics dependent on microtubule-associated proteins

1994 • 411 citations

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1997 • 343 citations

Apoptosis and the cell cycle

1995 • 334 citations

Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.

1995 • 324 citations

Granzyme B Directly and Efficiently Cleaves Several Downstream Caspase Substrates: Implications for CTL-Induced Apoptosis

1998 • 316 citations

Cell cycle checkpoints

1994 • 284 citations

Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage.

1996 • 266 citations

The display of microtubules in transformed cells

1977 • 223 citations

Cell Cycle-dependent Regulation of the Cyclin B1 Promoter

1995 • 123 citations

Interaction Site of GTP Binding Gh (Transglutaminase II) with Phospholipase C

1995 • 114 citations