Humoral Immunity Due to Long-Lived Plasma Cells

Immunological Memory and Protective Immunity: Understanding Their Relation

1996 • 1,771 citations

The Th1/Th2 paradigm

1997 • 1,102 citations

Basic and Clinical Immunology.

1979 • 790 citations

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.

1984 • 782 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

ON IMMUNOLOGICAL MEMORY

1996 • 482 citations

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

1997 • 437 citations

The half-lives of serum immunoglobulins in adult mice

1988 • 425 citations

Bone marrow is a major site of long-term antibody production after acute viral infection

1995 • 384 citations

The bone marrow: the major source of serum immunoglobulins, but still a neglected site of antibody formation.

1981 • 359 citations

Follicular Dendritic Cells as Accessory Cells

1990 • 351 citations

Maintenance of B-cell memory by long-lived cells generated from proliferating precursors

1990 • 323 citations

Distinct short‐lived and long‐lived antibody‐producing cell populations

1986 • 276 citations

Microanatomy of Lymphoid Tissue During Humoral Immune Responses: Structure Function Relationships

1989 • 253 citations

AUTORADIOGRAPHIC STUDIES ON THE IMMUNE RESPONSE

1962 • 235 citations

Sequential Expression of Immunoglobulin on Developing Mouse B Lymphocytes: A Systematic Survey That Suggests a Model for the Generation of Immunoglobulin Isotype Diversity

1978 • 211 citations

Maturation and Dispersal of B‐Cell Clones during T Cell‐Dependent Antibody Responses

1992 • 206 citations

T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses

1988 • 205 citations

Lymphocytic Choriomeningitis: Production of Antibody by "Tolerant" Infected Mice

1967 • 200 citations

MYELOMATOUS OSTEOSCLEROSIS AND PERIPHERAL NEUROPATHY

1965 • 188 citations

THE IMMUNOGLOBULINS OF MICE

1965 • 169 citations

The germinal center: a crucible for lymphocyte selection

1996 • 166 citations

Limiting dilution analysis of the B cell compartment in human bone marrow

1986 • 162 citations

Patterns of Expression of Human “Ia-Like” Antigens during the Terminal Stages of B Cell Development

1978 • 160 citations

Basic and Clinical Immunology

1982 • 160 citations

The Secretion of Antibody by Isolated Lymph Node Cells

1961 • 155 citations

AUTORADIOGRAPHIC STUDIES ON THE IMMUNE RESPONSE

1962 • 149 citations

Mode of interaction of mitomycin C with deoxyribonucleic acid and other polynucleotides in vitro

1974 • 147 citations

Memory B lymphocytes migrate to bone marrow in humans

1997 • 145 citations

Germinal center B cells and antibody production in the bone marrow.

1991 • 130 citations

Autoradiographic Observations of Plasma Cell Formation

1961 • 128 citations

THE IMMUNOGLOBULINS OF MICE

1964 • 113 citations

IMMUNITY AGAINST DIPHTHERIA 25-30 YEARS AFTER PRIMARY VACCINATION IN CHILDHOOD

1985 • 112 citations

Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity

1996 • 107 citations

Limiting dilution analysis of virus-specific memory B cells by an ELISPOT assay

1996 • 103 citations

Persistence of memory B cells in mice deprived of T cell help

1990 • 95 citations

Respiratory virus infection of mice provokes a permanent humoral immune response

1994 • 90 citations

An Autoradiographic Study of Plasma Cell and Lymphocyte Survival in Rat Popliteal Lymph Nodes

1964 • 89 citations

Radiosensitivity of Spleen Cells from Normal and Preimmunized Mice and Its Significance to Intact Animals

1962 • 78 citations

Reaginic antibody formation in the mouse

1981 • 76 citations

How many specific B cells are needed to protect against a virus?

1994 • 69 citations

B‐T Lymphocyte Interactions in the Generation and Survival of Memory Cells

1996 • 68 citations

Long-Term Immunity to Tetanus—A Statistical Evaluation and its Clinical Implications

1964 • 65 citations

The immune response of the mouse to lymphocytic choriomeningitis virus

1983 • 64 citations

VIRUS AND IMMUNE RESPONSES: LYMPHOCYTIC CHORIOMENINGITIS VIRUS AS A PROTOTYPE MODEL OF VIRAL PATHOGENESIS

1985 • 47 citations

Synthesis of antibody by spleen cells after exposure to kiloroentgen doses of ionizing radiation

1967 • 43 citations

The Bone Marrow

1982 • 43 citations

The immune response of the mouse to lymphocytic choriomeningitis virus. IV. Enumeration of antibody-producing cells in spleens during acute and persistent infection.

1984 • 39 citations

Production of lymphocytes and plasma cells in the rat following immunization with human serum albumin.

1961 • 32 citations

Catabolism of homologous murine monoclonal hybridoma IgG antibodies in mice.

1987 • 26 citations

The majority of “natural” immunoglobulin‐secreting cells are short‐lived and the progeny of cycling lymphocytes

1987 • 26 citations

Immunological memory: a function of antigen persistence

1993 • 24 citations

Effects of irradiation on the in vitro immune response.

1980 • 17 citations

THE LACK OF MEMORY B CELLS IN IMMUNE BONE MARROW

1991 • 12 citations