Decreased HPV-specific T cell responses and accumulation of immunosuppressive influences in oropharyngeal cancer patients following radical therapy

Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

2010 • 5,874 citations

Improved Survival of Patients With Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma in a Prospective Clinical Trial

2008 • 2,660 citations

Case–Control Study of Human Papillomavirus and Oropharyngeal Cancer

2007 • 2,615 citations

HPV-associated head and neck cancer: a virus-related cancer epidemic

2010 • 1,740 citations

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

2010 • 1,030 citations

Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

2009 • 1,027 citations

Mechanisms of Human Papillomavirus-Induced Oncogenesis

2004 • 1,002 citations

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

2005 • 1,000 citations

A New Population of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Induces CD4+CD25+Foxp3+ T Cells

2008 • 751 citations

Oral Squamous Cell Carcinoma

2005 • 750 citations

Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

2006 • 726 citations

Evidence for a Role of the PD-1:PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma

2013 • 721 citations

PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

2012 • 587 citations

A general primer GP5+/GP6(+)-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings

1997 • 571 citations

Prognostic Value of Tumor-Infiltrating CD4+ T-Cell Subpopulations in Head and Neck Cancers

2006 • 561 citations

Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance.

2002 • 375 citations

Tissue Distribution of Human Papillomavirus 16 DNA Integration in Patients with Tonsillar Carcinoma

2005 • 321 citations

Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties

2010 • 295 citations

The Frequency and Suppressor Function of CD4+CD25highFoxp3+ T Cells in the Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck

2007 • 273 citations

Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer

2005 • 271 citations

The molecular basis of the memory T cell response: differential gene expression and its epigenetic regulation

2012 • 269 citations

Immune Response During Therapy With Cisplatin or Radiation for Human Papillomavirus–Related Head and Neck Cancer

2009 • 237 citations

Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter.

2003 • 211 citations

The Relationship Between Human Papillomavirus Status and Other Molecular Prognostic Markers in Head and Neck Squamous Cell Carcinomas

2009 • 210 citations

Immunogenic Tumor Cell Death Induced by Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma

2012 • 201 citations

Human Circulating CD4+CD25highFoxp3+ Regulatory T Cells Kill Autologous CD8+ but Not CD4+ Responder Cells by Fas-Mediated Apoptosis

2009 • 194 citations

The Suppressive Tumor Microenvironment: A Challenge in Cancer Immunotherapy

2011 • 189 citations

Immune Suppression in Head and Neck Cancers: A Review

2010 • 177 citations

Increased Ectonucleotidase Expression and Activity in Regulatory T Cells of Patients with Head and Neck Cancer

2009 • 166 citations

Correlation of Cellular Immunity With Human Papillomavirus 16 Status and Outcome in Patients With Advanced Oropharyngeal Cancer

2010 • 114 citations

Myeloid-Derived Suppressor Cells Interact with Tumors in Terms of Myelopoiesis, Tumorigenesis and Immunosuppression: Thick as Thieves

2013 • 106 citations

Systemic and local human papillomavirus 16‐specific T‐cell immunity in patients with head and neck cancer

2011 • 101 citations

T cells specific for HPV16 E7 epitopes in patients with squamous cell carcinoma of the oropharynx

2005 • 90 citations

CD8‐alpha T‐cell infiltration in human papillomavirus‐related oropharyngeal carcinoma correlates with improved patient prognosis

2012 • 87 citations

Combination Chemotherapy and Radiation of Human Squamous Cell Carcinoma of the Head and Neck Augments CTL-Mediated Lysis

2006 • 85 citations

Effector CD8+CD45RO−CD27−T cells have signalling defects in patients with squamous cell carcinoma of the head and neck

2003 • 76 citations

HPV16 semiquantitative viral load and serologic biomarkers in oral and oropharyngeal squamous cell carcinomas

2005 • 71 citations

Homeostatic Turnover of Virus-Specific Memory CD8 T Cells Occurs Stochastically and Is Independent of CD4 T Cell Help

2010 • 66 citations

Immunotherapy of Head and Neck Cancer: Current and Future Considerations

2009 • 61 citations

The clinical implications of antitumor immunity in head and neck cancer

2011 • 57 citations

Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

2010 • 45 citations

Human papillomavirus infection: an Anonymous Prevalence Study in South Wales, UK

2006 • 35 citations

Epitope specificity and longevity of a vaccine-induced human T cell response against HPV18

2004 • 28 citations

Immunotherapy for head and neck cancer

2010 • 23 citations

Spontaneous apoptosis of tumor‐specific tetramer⁺ CD8⁺ T lymphocytes in the peripheral circulation of patients with head and neck cancer

2009 • 19 citations

Immunotherapy for head and neck cancer

2009 • 13 citations

Radiochemotherapy fosters a favorable pattern of inflammatory cells in head and neck tumors

2012 • 4 citations

OP027

2013 • 2 citations