Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance.

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS

1999 • 1,309 citations

MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

1999 • 973 citations

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

1998 • 789 citations

Fas ligand in human serum

1996 • 682 citations

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

1999 • 598 citations

Inhibition of Fas death signals by FLIPs

1998 • 531 citations

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x_L

1999 • 295 citations

Mechanisms of immune suppression in patients with head and neck cancer: presence of CD34(+) cells which suppress immune functions within cancers that secrete granulocyte-macrophage colony-stimulating factor.

1995 • 272 citations

Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines.

1989 • 254 citations

Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes.

1999 • 218 citations

Mechanisms of immune suppression in patients with head and neck cancer: Influence on the immune infiltrate of the cancer

1996 • 178 citations

Tumor-induced death of immune cells: its mechanisms and consequences

2002 • 154 citations

Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma.

1998 • 147 citations

Clinical significance of decreased zeta chain expression in peripheral blood lymphocytes of patients with head and neck cancer.

1999 • 138 citations

Decreased zeta chain expression and apoptosis in CD3+ peripheral blood T lymphocytes of patients with melanoma.

2001 • 128 citations

Caspase-mediated degradation of T-cell receptor zeta-chain.

1999 • 118 citations

Spontaneous ex vivo apoptosis of peripheral blood mononuclear cells in patients with head and neck cancer.

1999 • 112 citations

Spontaneous apoptosis of CD8+ T lymphocytes in peripheral blood of patients with advanced melanoma.

2000 • 110 citations

Advances in the Stable Isotope–Mass Spectrometric Measurement of DNA Synthesis and Cell Proliferation

2001 • 104 citations

Release of preformed Fas ligand in soluble form is the major factor for activation‐induced death of Jurkat T cells

1996 • 94 citations

PROGNOSTIC SIGNIFICANCE OF SOLUBLE FAS IN THE SERUM OF PATIENTS WITH BLADDER CANCER

1998 • 89 citations

Soluble Fas in serum from patients with renal cell carcinoma

2000 • 40 citations

Relationship between Fas-ligand expression on carcinoma cell and cytotoxic T-lymphocyte response in lymphoepithelioma-like cancer of the stomach

1999 • 36 citations

Contribution of serum inhibitory factors and immune cellular defects to the depressed cell-mediated immunity in patients with head and neck cancer

1993 • 34 citations

Characterization of T Lymphocyte Subset Alterations by Flow Cytometry in HIV Disease

1993 • 32 citations

Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes

1999 • 26 citations

Inhibition of peripheral blood lymphocyte apoptosis by soluble fas ligand in patients with hepatocellular carcinoma.

1999 • 13 citations