Augmentation of locomotor activity by chronic phencyclidine is associated with an increase in striatal NMDA receptor function and an upregulation of the NR1 receptor subunit

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Neurotransmitters and neuromodulators in the basal ganglia

1990 • 1,578 citations

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

1983 • 1,400 citations

The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones

1990 • 1,021 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Structure and function of the NMDA receptor channel

1995 • 645 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

Modulatory functions of neurotransmitters in the striatum: ACh/dopamine/NMDA interactions

1994 • 469 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine

1994 • 420 citations

Subchronic Phencyclidine Administration Reduces Mesoprefrontal Dopamine Utilization and Impairs Prefrontal Cortical-Dependent Cognition in the Rat

1997 • 320 citations

The role of specific ions in glutamate neurotoxicity

1986 • 298 citations

MODEL PSYCHOSES AND SCHIZOPHRENIA

1962 • 269 citations

Neostriatal cell subtypes and their functional roles

1997 • 268 citations

Comparison of the effects of MK-801 and phencyclidine on catecholamine uptake and NMDA-induced norepinephrine release

1988 • 240 citations

Repeated administration of MK-801 produces sensitization to its own locomotor stimulant effects but blocks sensitization to amphetamine

1991 • 238 citations

Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotypes behavior and ataxia in rats

1979 • 236 citations

Effects of phencyclidine on [3H]catecholamine and [3H]serotonin uptake in synaptosomal preparations from rat brain

1977 • 214 citations

The effect of cholinergic drugs on [3H]acetylcholine release from slices of rat hippocampus, striatum and cortex

1977 • 191 citations

Characterization of the inhibition of excitatory amino acid-induced neurotransmitter release in the rat striatum by phencyclidine-like drugs.

1986 • 187 citations

The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity

1984 • 181 citations

Cellular and molecular neurotoxicology

1985 • 131 citations

Phencyclidine-induced stereotyped behavior in rats: Dose response effects and antagonism by neuroleptics

1979 • 125 citations

D-serine antagonized phencyclidine- and MK-801-induced stereotyped behavior and ataxia

1990 • 120 citations

The glycine/NMDA receptor antagonist, R‐(+)‐HA‐966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK‐801) in rodents

1993 • 94 citations

Chronic phencyclidine induces behavioral sensitization and apoptotic cell death in the olfactory and piriform cortex

1998 • 92 citations

Similar dopamine-releasing effects of phencyclidine and nonamphetamine stimulants in striatal slices.

1982 • 85 citations

Stereotyped behavior correlates better than ataxia with phencyclidine-receptor interactions

1986 • 79 citations

Effects of phencyclidine on ventral tegmental A10 dopamine neurons in the rat

1986 • 68 citations

Alterations in local cerebral glucose utilization induced by phencyclidine

1987 • 68 citations

Effect of lesions in the striatum. nucleus accumbens and medial raphe on phencyclidine-induced stereotyped behaviors and hyperactivity in rats

1983 • 61 citations

Behavioral effects of chronic phencyclidine administration in rats

1982 • 60 citations

Phencyclidine-induced behavioral sensitization

1994 • 57 citations

The non-competitive NMDA antagonists MK-801 and PCP, as well as the competitive NMDA antagonist SDZ EAA494 (D-CPPene), interact synergistically with clonidine to promote locomotion in monoamine-depleted mice

1990 • 52 citations

PCP‐induced alterations in cerebral glucose utilization in rat brain: Blockade by metaphit, a PCP‐receptor‐acylating agent

1987 • 50 citations

Chronic phencyclidine treatment decreases phencyclidine and dopamine receptors in rat brain

1982 • 46 citations

Inhibition of N-methyl-D-aspartate glutamate receptor subunit expression by antisense oligonucleotides reveals their role in striatal motor regulation.

1996 • 43 citations

Postnatal phencyclidine treatment differentially regulates N -methyl- d -aspartate receptor subunit mRNA expression in developing rat cerebral cortex

1996 • 39 citations

Stereoselective inhibition by d- and l-alanine of phencyclidine-induced locomotor stimulation in the rat

1991 • 37 citations

Measurement of Brain Compartment Volumes in MR using Voxel Composition Calculations

1991 • 29 citations

Chronic phencyclidine, like amphetamine, produces a decrease in [3H]spiroperidol binding in rat striatum

1982 • 26 citations

Phencyclidine-induced increases in striatal neuron firing in behaving rats: reversal by haloperidol and clozapine

1995 • 19 citations

Asymmetric cross-sensitization to the locomotor stimulant effects of phencyclidine and MK-801

1994 • 18 citations

The effect of phencyclidine on the turnover rate of acetylcholine in various regions of rat brain.

1981 • 12 citations

Changes in dopamine D2 and GluR-1 glutamate receptor mRNAs in the rat brain after treatment with phencyclidine.

1995 • 8 citations