The glycine/NMDA receptor antagonist, R‐(+)‐HA‐966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK‐801) in rodents

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1982 • 409 citations

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1984 • 348 citations

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1984 • 199 citations

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1988 • 146 citations

Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative.

1990 • 135 citations

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1987 • 133 citations

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1990 • 120 citations

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1983 • 108 citations

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1987 • 91 citations

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1984 • 88 citations

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1982 • 85 citations

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1985 • 76 citations

R‐(+)‐HA‐966, a glycine/NMDA receptor antagonist, selectively blocks the activation of the mesolimbic dopamine system by amphetamine

1991 • 75 citations

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1987 • 71 citations

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1990 • 71 citations

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1986 • 70 citations

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1983 • 68 citations

Phencyclidine binding sites in the nucleus accumbens and phencyclidine-induced hyperactivity are decreased following lesions of the mesolimbic dopamine system

1985 • 65 citations

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1984 • 59 citations

The discriminative stimulus effects of N-methyl-d-aspartate antagonists in phencyclidine-trained rats

1988 • 56 citations

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1989 • 55 citations

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1989 • 54 citations

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1984 • 50 citations

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1983 • 50 citations

The discriminative stimulus properties of (+)-HA-966, an antagonist at the glycine/N-methyl-D-aspartate receptor

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1980 • 43 citations

Homovanillic acid in rat caudate and prefrontal cortex following phencyclidine and amphetamine

1984 • 42 citations

Stereoselective inhibition by d- and l-alanine of phencyclidine-induced locomotor stimulation in the rat

1991 • 37 citations

Evidence against an involvement of the haloperidol‐sensitive σ recognition site in the discriminative stimulus properties of (+)‐N‐allylnormetazocine ((+)‐SKF 10,047)

1990 • 33 citations

Effects of antiischemic drugs on veratridine-induced hypercontracture in rat cardiac myocytes

1994 • 30 citations

Hyperactivity induced by N-methyl-d-aspartate injections into nucleus accumbens: Lack of evidence for mediation by dopaminergic neurons

1989 • 27 citations

Effects of an N-methyl-d-aspartate receptor agonist and its antagonist CPP on the levels of dopamine and serotonin metabolites in rat striatum collected in vivo by using a brain dialysis technique

1989 • 25 citations

Competitive NMDA receptor antagonists attenuate phencyclidine-induced excitations of A10 dopamine neurons

1992 • 22 citations

Activation of postsynaptic striatal dopamine receptors, monitored by efflux of cAMP in vivo

1990 • 14 citations