The role of specific ions in glutamate neurotoxicity

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Calcium Dependence of Toxic Cell Death: A Final Common Pathway

1979 • 1,478 citations

Kainic acid as a tool in neurobiology

1978 • 1,314 citations

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death

1984 • 893 citations

An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid

1982 • 834 citations

Glutamate neurotoxicity in cortical cell culture is calcium dependent

1985 • 818 citations

Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system

1971 • 808 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

Schizophrenia: Some Current Neurochemical Approaches

1983 • 459 citations

Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

1984 • 416 citations

GLUTAMATE-INDUCED NEURONAL NECROSIS IN THE INFANT MOUSE HYPOTHALAMUS

1971 • 409 citations

Excitotoxic mechanisms of epileptic brain damage.

1986 • 389 citations

GLUTAMATE—INDUCED RETINAL DEGENERATION IN NEONATAL MICE. ELECTRON MICROSCOPY OF THE ACUTELY EVOLVING LESION

1969 • 352 citations

N‐methyl aspartate activates voltage‐dependent calcium conductance in rat hippocampal pyramidal cells.

1983 • 281 citations

Abnormal Glutamate Metabolism in an Adult-Onset Degenerative Neurological Disorder

1982 • 227 citations

Neurotoxin induced nerve cell degeneration: Possible involvement of calcium

1984 • 166 citations

Toxic Injury to Isolated Hepatocytes Is Not Dependent on Extracellular Calcium

1981 • 164 citations

Kainate, N-methylaspartate and other excitatory amino acids increase calcium influx into rat brain cortex cells in vitro

1983 • 156 citations

Cysteine-S-Sulfate: Brain Damaging Metabolite in Sulfite Oxidase Deficiency1

1975 • 137 citations

Vitamin E Reversal of the Effect of Extracellular Calcium on Chemically Induced Toxicity in Hepatocytes

1985 • 132 citations

Selective antagonism by Mg2+ of amino acid-induced depolarization of spinal neurones

1977 • 108 citations

Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina

1985 • 74 citations

ROLE OF CALCIUM IN CYTOTOXIC INJURY OF CULTURED HEPATOCYTES*

1983 • 51 citations

Effects of monosodium glutamate on chick embryo retina in culture.

1975 • 34 citations

Substitution of extracellular sodium ions blocks the voltage-dependent decrease of input conductance evoked by <scp>L</scp>-aspartate

1984 • 19 citations

Huntington’s Disease: Anti-Neurotoxic Therapeutic Strategies

1983 • 18 citations