Characterisation of human and murine snRNP proteins by two-dimensional gel electrophoresis and phosphopeptide analysis of U1-specific 70K protein variants

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Antinuclear Antibodies: Diagnostic Markers for Autoimmune Diseases and Probes for Cell Biology

1989 • 1,543 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

PRE-mRNA SPLICING

1986 • 673 citations

Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots

1984 • 668 citations

The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing

1987 • 594 citations

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

1983 • 593 citations

Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F.

1987 • 494 citations

SPLICEOSOMAL snRNAs

1988 • 463 citations

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.

1984 • 371 citations

A protein associated with small nuclear ribonucleoprotein particles recognizes the 3′ splice site of premessenger RNA

1986 • 283 citations

Cloning of the human cDNA for the U1 RNA-associated 70K protein.

1986 • 235 citations

Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-dalton mammalian stress proteins.

1985 • 233 citations

Purification of the individual snRNPs U1, U2, U5 and U4/U6 from HeLa cells and characterization of their protein constituents.

1986 • 170 citations

Soluble acidic complexes containing histones H3 and H4 in nuclei of Xenopus laevis oocytes

1982 • 158 citations

Multiple phosphorylation of ribosomal protein S6 during transition of quiescent 3T3 cells into early G1, and cellular compartmentalization of the phosphate donor.

1979 • 151 citations

20S small nuclear ribonucleoprotein U5 shows a surprisingly complex protein composition.

1989 • 148 citations

Purification of snRNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1)RNP antisera.

1983 • 143 citations

U1-Specific Protein C needed for Efficient Complex Formation of U1 snRNP with a 5′ Splice Site

1990 • 135 citations

A monoclonal antibody against 2,2,7‐trimethylguanosine that reacts with intact, class U, small nuclear ribonucleoproteins as well as with 7‐methylguanosine‐capped RNAs

1987 • 133 citations

Small nuclear ribonucleoprotein particle assembly in vivo: Demonstration of a 6S RNA-free core precursor and posttranslational modification

1985 • 125 citations

Subnuclear particles containing a small nuclear RNA and heterogeneous nuclear RNA

1981 • 96 citations

Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-Sm and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal antibodies.

1986 • 87 citations

Cloned human snRNP proteins B and B' differ only in their carboxy-terminal part.

1989 • 87 citations

Autoantibodies to ribonucleoprotein particles containing U2 small nuclear RNA.

1985 • 85 citations

Further characterization and subcellular localization of Sm and Ul ribonucleoprotein antigens

1985 • 71 citations

Small nuclear RNA associated proteins: autoantigens in connective tissue diseases.

1989 • 65 citations

Identification of human Sm and (U1) RNP antigens by immunoblotting

1983 • 63 citations

Synthesis and assembly of human small nuclear ribonucleoproteins generated by cell-free translation.

1983 • 57 citations

Fine specificities of autoantibodies directed against the Ro, La, Sm, RNP, and Jo-1 proteins defined by two-dimensional gel electrophoresis and immunoblotting.

1985 • 57 citations

Cytoplasmic Assembly and Nuclear Accumulation of Mature Small Nuclear Ribonucleoprotein Particles

1989 • 52 citations

Polypeptide components of human small nuclear ribonucleoproteins.

1983 • 35 citations

Molecular relationships between U snRNP proteins as investigated by rabbit antisera and peptide mapping

1987 • 34 citations

Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiationin situ

1988 • 28 citations

Structure of mutant and wild-type MC29 v-myc alleles and biochemical properties of their protein products.

1987 • 24 citations

Autoantibody production against the U small nuclear ribonucleoprotein particle proteins E, F and G in patients with connective tissue diseases

1990 • 22 citations

Identification of an antigenic protein recognized by anti-Sm autoantibody

1982 • 11 citations

Isofocusing of antigenic small nuclear ribonucleoproteins

1985 • 6 citations