The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A

1975 • 3,054 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

Autoantibodies to Nuclear Antigens (ANA): Their Immunobiology and Medicine

1982 • 975 citations

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.

1981 • 725 citations

Transfer of proteins from gels to diazobenzyloxymethyl-paper and detection with antisera: a method for studying antibody specificity and antigen structure.

1979 • 722 citations

Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus

2001 • 551 citations

SnRNAs, SnRNPs, and RNA Processing

1982 • 458 citations

Characteristics of a Soluble Nuclear Antigen Precipitating with Sera of Patients with Systemic Lupus Erythematosus

1966 • 452 citations

Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells.

1981 • 384 citations

Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein

1983 • 333 citations

Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus description of a cytoplasmic nonribosomal antigen

1974 • 291 citations

Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs.

1983 • 245 citations

A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences.

1981 • 243 citations

Differentiation of antinuclear antibodies giving speckled staining patterns in immunofluorescence

1972 • 238 citations

Characterization of a Soluble Nuclear Ribonucleoprotein Antigen Reactive with Sle Sera

1971 • 218 citations

Anti-RNP monoclonal antibodies derived from a mouse strain with lupus-like autoimmunity.

1982 • 192 citations

Structural organization of ribonucleoproteins containing small nuclear RNAs from HeLa cells

1982 • 184 citations

Autoantibodies to the U2 small nuclear ribonucleoprotein in a patient with scleroderma-polymyositis overlap syndrome.

1984 • 178 citations

Antibodies to histones in systemic lupus erythematosus: localization of prominent autoantigens on histones H1 and H2B.

1983 • 158 citations

Physical Association of Two Nuclear Antigens and Mutual Occurrence of Their Antibodies: The Relationship of the Sm and Rnaprotein (MO) Systems in Sle Sera

1973 • 145 citations

Purification of snRNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1)RNP antisera.

1983 • 143 citations

Fractionation and characterization of human small nuclear ribonucleoproteins containing U1 and U2 RNAs.

1983 • 126 citations

Antibodies from patients with connective tissue diseases bind specific subsets of cellular RNA-protein particles.

1982 • 122 citations

Human anticentromere antibodies: Distribution, characterization of antigens, and effect on microtubule organization

1983 • 120 citations

Molecular characterization of ribonucleoprotein antigens bound by antinuclear antibodies. A diagnostic evaluation

1982 • 117 citations

Antibodies against distinct nuclear matrix proteins are characteristic for mixed connective tissue disease.

1983 • 114 citations

Molecular relationships between two nuclear antigens, ribonucleoprotein and Sm: purification of active antigens and their biochemical characterization

1981 • 83 citations

The glycosaminoglycans in menisci in experimental and natural osteoarthritis

1983 • 82 citations

Isolation and characterization of nuclear ribonucleoprotein complexes using human anti-nuclear ribonucleoprotein antibodies.

1979 • 78 citations

Small Ribonucleoproteins from Eukaryotes: Structures and Roles in RNA Biogenesis

1983 • 75 citations

Autoantibodies to Nucleosomal Proteins: Antibodies to HMG-17 in Autoimmune Diseases

1982 • 74 citations

Protein antigens of the RNA-protein complexes detected by anti-SM and anti-RNP antibodies found in serum of patients with systemic lupus erythematosus and related disorders.

1982 • 74 citations

Definition of the antigenic polypeptides in the Sm and RNP ribonucleoprotein complexes

1981 • 73 citations

Identification of human Sm and (U1) RNP antigens by immunoblotting

1983 • 63 citations

Assays for the Sm and RNP autoantigens: the requirement for RNA and influence of the tissue source.

1982 • 58 citations

Synthesis and assembly of human small nuclear ribonucleoproteins generated by cell-free translation.

1983 • 57 citations

Human U1 and U2 small nuclear ribonucleoproteins contain common and unique polypeptides.

1982 • 55 citations

Identification of the immunogenically active components of the Sm and RNP antigens.

1981 • 53 citations

Polypeptide components of human small nuclear ribonucleoproteins.

1983 • 35 citations

Anti-Tissue Antibodies in Rheumatic Disease

1977 • 32 citations

Nuclear ribonucleoproteins recognized by human antinuclear antibodies in retrovirus-infected cells

1981 • 19 citations

Nucleosomes as antigens

1982 • 13 citations