The Proteasome Restricts Permissive Transcription at Tissue-Specific Gene Loci in Embryonic Stem Cells

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

2005 • 4,388 citations

Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

2003 • 1,422 citations

Histone H3 Methylation by Set2 Directs Deacetylation of Coding Regions by Rpd3S to Suppress Spurious Intragenic Transcription

2005 • 1,286 citations

Proteasomes and their kin: proteases in the machine age

2004 • 727 citations

Cyclic, Proteasome-Mediated Turnover of Unliganded and Liganded ERα on Responsive Promoters Is an Integral Feature of Estrogen Signaling

2003 • 718 citations

Chromatin in pluripotent embryonic stem cells and differentiation

2006 • 665 citations

Controlling nuclear receptors: the circular logic of cofactor cycles

2005 • 499 citations

Endoproteolytic Activity of the Proteasome

2003 • 425 citations

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

1996 • 410 citations

A transcription reinitiation intermediate that is stabilized by activator

2000 • 407 citations

MYC recruits the TIP60 histone acetyltransferase complex to chromatin

2003 • 379 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

The 19S Regulatory Particle of the Proteasome Is Required for Efficient Transcription Elongation by RNA Polymerase II

2001 • 266 citations

The SRC-3/AIB1 Coactivator Is Degraded in a Ubiquitin- and ATP-Independent Manner by the REGγ Proteasome

2006 • 265 citations

The proteasome: a utility tool for transcription?

2006 • 243 citations

Multiple Mechanisms Confining RNA Polymerase II Ubiquitylation to Polymerases Undergoing Transcriptional Arrest

2005 • 215 citations

Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex

2002 • 198 citations

Molecular Machines for Protein Degradation

2005 • 197 citations

When the SWI/SNF complex remodels … the cell cycle

2001 • 196 citations

Distinct TFIID complexes mediate the effect of different transcriptional activators.

1993 • 189 citations

20S proteasomes and protein degradation “by default”

2006 • 187 citations

A putative stimulatory role for activator turnover in gene expression

2005 • 180 citations

The Proteasome Regulatory Particle Alters the SAGA Coactivator to Enhance Its Interactions with Transcriptional Activators

2005 • 179 citations

A Mechanism for Coordinating Chromatin Modification and Preinitiation Complex Assembly

2006 • 163 citations

The F Box Protein Dsg1/Mdm30 Is a Transcriptional Coactivator that Stimulates Gal4 Turnover and Cotranscriptional mRNA Processing

2005 • 157 citations

Physical and functional association of RNA polymerase II and the proteasome

2004 • 155 citations

c-Myc Transformation Domain Recruits the Human STAGA Complex and Requires TRRAP and GCN5 Acetylase Activity for Transcription Activation

2003 • 147 citations

Formation of an Active Tissue-Specific Chromatin Domain Initiated by Epigenetic Marking at the Embryonic Stem Cell Stage

2005 • 130 citations

RETRACTED: ATP Hydrolysis-Dependent Disassembly of the 26S Proteasome Is Part of the Catalytic Cycle

2005 • 121 citations

The role of enhancers as centres for general transcription factor recruitment

2005 • 118 citations

Genomic Association of the Proteasome Demonstrates Overlapping Gene Regulatory Activity with Transcription Factor Substrates

2006 • 109 citations

A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction.

2004 • 102 citations

The multicoloured world of promoter recognition complexes

2003 • 95 citations

A New Twist in the Feedback Loop: Stress-Activated MDM2 Destabilization is Required for p53 Activation

2005 • 90 citations

20S Proteasome Differentially Alters Translation of Different mRNAs via the Cleavage of eIF4F and eIF3

2004 • 84 citations

Analysis of a Gene Encoding Rpn10 of the Fission Yeast Proteasome Reveals That the Polyubiquitin-binding Site of This Subunit Is Essential When Rpn12/Mts3 Activity Is Compromised

2000 • 83 citations

A Dynamic Switch in the Replication Timing of Key Regulator Genes in Embryonic Stem Cells upon Neural Induction

2004 • 79 citations

Highly Restricted Localization of RNA Polymerase II within a Locus Control Region of a Tissue-Specific Chromatin Domain

2003 • 78 citations

Recruitment of Transcription Complexes to the β-Globin Gene Locus in Vivo and in Vitro

2004 • 68 citations

Sequential Histone Modifications at Hoxd4 Regulatory Regions Distinguish Anterior from Posterior Embryonic Compartments

2004 • 68 citations

Hyperacetylated Chromatin Domains: Lessons from Heterochromatin

2005 • 64 citations

Widespread, but Non-identical, Association of Proteasomal 19 and 20 S Proteins with Yeast Chromatin

2006 • 64 citations

The epigenetic basis for embryonic stem cell pluripotency

2005 • 63 citations

Definition of Transcriptional Promoters in the Human β Globin Locus Control Region

2002 • 60 citations

Analysis of Mice with Single and Multiple Copies of Transgenes Reveals a Novel Arrangement for the λ5-V_preB1Locus Control Region

1999 • 51 citations

Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription

2006 • 45 citations

The λ5–VpreB1 locus—a model system for studying gene regulation during early B cell development

2005 • 25 citations

Mapping and functional analysis of regulatory sequences in the mouse λ5-VpreB1 domain

2005 • 7 citations