Analysis of a Gene Encoding Rpn10 of the Fission Yeast Proteasome Reveals That the Polyubiquitin-binding Site of This Subunit Is Essential When Rpn12/Mts3 Activity Is Compromised

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

[56] Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

1991 • 3,691 citations

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

1995 • 1,513 citations

A Novel Ubiquitination Factor, E4, Is Involved in Multiubiquitin Chain Assembly

1999 • 1,031 citations

Thiamine-repressible expression vectors pREP and pRIP for fission yeast

1993 • 1,013 citations

A Subcomplex of the Proteasome Regulatory Particle Required for Ubiquitin-Conjugate Degradation and Related to the COP9-Signalosome and eIF3

1998 • 901 citations

A Proteolytic Pathway That Recognizes Ubiquitin as a Degradation Signal

1995 • 804 citations

A 26 S protease subunit that binds ubiquitin conjugates.

1994 • 759 citations

A Ubiquitin Mutant with Specific Defects in DNA Repair and Multiubiquitination

1995 • 547 citations

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

1990 • 520 citations

The Regulatory Particle of the Saccharomyces cerevisiae Proteasome

1998 • 487 citations

The base of the proteasome regulatory particle exhibits chaperone-like activity

1999 • 485 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

Ubiquitin-mediated protein degradation.

1988 • 453 citations

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

1993 • 422 citations

The Multiubiquitin-Chain-Binding Protein Mcb1 Is a Component of the 26S Proteasome in Saccharomyces cerevisiae and Plays a Nonessential, Substrate-Specific Role in Protein Turnover

1996 • 393 citations

Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

1996 • 390 citations

Characterization of Two Polyubiquitin Binding Sites in the 26 S Protease Subunit 5a

1998 • 307 citations

Selective protein degradation: A journey's end within the proteasome

1995 • 259 citations

Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit

1993 • 244 citations

Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting.

1996 • 240 citations

Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain.

1994 • 238 citations

Autocatalytic processing of the 20S proteasome

1996 • 226 citations

High efficiency transformation ofSchizosaccharomyces pombeby electroporation

1992 • 220 citations

Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast

1998 • 212 citations

Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.

1996 • 191 citations

Multiubiquitin Chain Binding and Protein Degradation Are Mediated by Distinct Domains within the 26 S Proteasome Subunit Mcb1

1998 • 174 citations

Pleiotropic Defects Caused by Loss of the Proteasome-Interacting Factors Rad23 and Rpn10 of Saccharomyces cerevisiae

1999 • 155 citations

Localization of the 26S proteasome during mitosis and meiosis in fission yeast

1998 • 152 citations

Arabidopsis MBP1 gene encodes a conserved ubiquitin recognition component of the 26S proteasome.

1996 • 143 citations

Subunits of the regulatory complex of the 26S protease

1995 • 127 citations

Interaction of the Doa4 Deubiquitinating Enzyme with the Yeast 26S Proteasome

1999 • 126 citations

A Conditional Lethal Mutant in the Fission Yeast 26 S Protease Subunit mts3+ Is Defective in Metaphase to Anaphase Transition

1996 • 110 citations

Ubiquitin-lysozyme conjugates. Purification and susceptibility to proteolysis.

1986 • 108 citations

Structural Features of 26S and 20S Proteasomes

1993 • 107 citations

Multiubiquitin Chain Binding Subunit MCB1 (RPN10) of the 26S Proteasome Is Essential for Developmental Progression in Physcomitrella patens

1999 • 97 citations

Multiubiquitin chains linked through lysine 48 are abundant in vivo and are competent intermediates in the ubiquitin proteolytic pathway.

1993 • 94 citations

Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae.

1995 • 94 citations

Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1.

1997 • 92 citations

Inhibition of Ubiquitin-mediated Proteolysis by the Arabidopsis 26 S Protease Subunit S5a

1995 • 90 citations

Molecular Structures of 20S and 26S Proteasomes

1993 • 79 citations

A Mutation in a Novel Yeast Proteasomal Gene,RPN11/MPR1, Produces a Cell Cycle Arrest, Overreplication of Nuclear and Mitochondrial DNA, and an Altered Mitochondrial Morphology

1998 • 74 citations

Molecular cloning and expression of a multiubiquitin chain binding subunit of the human 26S protease

1996 • 68 citations

Characteristics of 26 S Proteases from Fission Yeast Mutants, which Arrest in Mitosis

1996 • 65 citations

Cloning and Sequencing a Non-ATPase Subunit of the Regulatory Complex of the Drosophila 26S Protease

1995 • 62 citations

cDNA Cloning and Functional Analysis of the p97 Subunit of the 26S Proteasome, a Polypeptide Identical to the Type‐1 Tumor‐Necrosis‐Factor‐Receptor‐Associated Protein‐2/55.11

1996 • 56 citations

The pad1 + Gene Encodes a Subunit of the 26 S Proteasome in Fission Yeast

1998 • 47 citations

Mts4, a Non-ATPase Subunit of the 26 S Protease in Fission Yeast Is Essential for Mitosis and Interacts Directly with the ATPase Subunit Mts2

1997 • 46 citations

Mapping the ubiquitin‐binding domains in the p54 regulatory complex subunit of the Drosophila 26S protease

1997 • 44 citations

Molecular cloning and testicular expression of the gene transcripts encoding the murine multiubiquitin-chain-binding protein (Mcb1)

1998 • 12 citations