c-Myc Transformation Domain Recruits the Human STAGA Complex and Requires TRRAP and GCN5 Acetylase Activity for Transcription Activation

Histone Acetyltransferases

2001 • 1,745 citations

The Myc/Max/Mad Network and the Transcriptional Control of Cell Behavior

2000 • 1,307 citations

Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis

2000 • 994 citations

Acetylation of p53 Activates Transcription through Recruitment of Coactivators/Histone Acetyltransferases

2001 • 704 citations

The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins

1998 • 675 citations

Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

1989 • 614 citations

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation

2001 • 508 citations

The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc

2000 • 479 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo

2001 • 369 citations

Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter

2001 • 334 citations

The p400 Complex Is an Essential E1A Transformation Target

2001 • 323 citations

An ATPase/Helicase Complex Is an Essential Cofactor for Oncogenic Transformation by c-Myc

2000 • 314 citations

Deconstructing Myc: Figure 1.

2001 • 311 citations

FAT: a novel domain in PIK-related kinases

2000 • 300 citations

The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4

2001 • 287 citations

Myc Recruits P-TEFb to Mediate the Final Step in the Transcriptional Activation of the cad Promoter

2002 • 256 citations

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo

1999 • 220 citations

c-Myc Mediates Activation of the cad Promoter via a Post-RNA Polymerase II Recruitment Mechanism

2001 • 199 citations

Identification of TATA-binding Protein-free TAFII-containing Complex Subunits Suggests a Role in Nucleosome Acetylation and Signal Transduction

1999 • 181 citations

A Human SPT3-TAFII31-GCN5-L Acetylase Complex Distinct from Transcription Factor IID

1998 • 179 citations

Differential Requirement of SAGA Components for Recruitment of TATA-Box-Binding Protein to Promoters In Vivo

2002 • 179 citations

New Myc-interacting proteins: a second Myc network emerges

1999 • 178 citations

Function of the c-Myc oncoprotein in chromatin remodeling and transcription

2001 • 172 citations

BAF53 Forms Distinct Nuclear Complexes and Functions as a Critical c-Myc-Interacting Nuclear Cofactor for Oncogenic Transformation

2002 • 167 citations

The 400 kDa Subunit of the PCAF Histone Acetylase Complex Belongs to the ATM Superfamily

1998 • 160 citations

RETRACTED: Nuclear Receptor Function Requires a TFTC-Type Histone Acetyl Transferase Complex

2002 • 155 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis

2001 • 139 citations

TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins

2002 • 137 citations

Identification of Downstream-Initiated c-Myc Proteins Which Are Dominant-Negative Inhibitors of Transactivation by Full-Length c-Myc Proteins

1997 • 136 citations

Analysis of Spt7 Function in the Saccharomyces cerevisiae SAGA Coactivator Complex

2002 • 132 citations

Inhibition of TATA-Binding Protein Function by SAGA Subunits Spt3 and Spt8 at Gcn4-Activated Promoters

2000 • 130 citations

E2F Transcriptional Activation Requires TRRAP and GCN5 Cofactors

2001 • 128 citations

Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis

1998 • 120 citations

SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription

2002 • 119 citations

Transcriptional Regulation of the mdm2 Oncogene by p53 Requires TRRAP Acetyltransferase Complexes

2002 • 111 citations

Direct Examination of Histone Acetylation on Myc Target Genes Using Chromatin Immunoprecipitation

2000 • 90 citations

Recruitment of Gcn5-containing Complexes during c-Myc-dependent Gene Activation

2002 • 39 citations

TATA-binding Protein-free TAF-containing Complex (TFTC) and p300 Are Both Required for Efficient Transcriptional Activation

2002 • 36 citations

Differential activity of conditional MYC and its variant MYC-S in human mortal fibroblasts

2000 • 23 citations