Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex

The coregulator exchange in transcriptional functions of nuclear receptors

2000 • 2,219 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

Nuclear Receptor Coregulators: Cellular and Molecular Biology*

1999 • 1,783 citations

Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription

2000 • 1,658 citations

Themes and variations on ubiquitylation

2001 • 1,475 citations

Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators

2002 • 1,449 citations

Androgen Receptor Defects: Historical, Clinical, and Molecular Perspectives*

1995 • 1,432 citations

Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor.

1994 • 940 citations

Molecular Biology of the Androgen Receptor

2002 • 917 citations

Androgen Receptor (AR) Coregulators: An Overview

2002 • 876 citations

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1999 • 705 citations

Formation of the Androgen Receptor Transcription Complex

2002 • 657 citations

Regulation of Hormone-Induced Histone Hyperacetylation and Gene Activation via Acetylation of an Acetylase

1999 • 630 citations

Proteasome-dependent degradation of the human estrogen receptor

1999 • 573 citations

The 26S Proteasome Is Required for Estrogen Receptor-α and Coactivator Turnover and for Efficient Estrogen Receptor-α Transactivation

2000 • 561 citations

The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

2000 • 550 citations

Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1)

2000 • 448 citations

Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

2000 • 444 citations

Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex

1996 • 399 citations

Emerging Roles of Ubiquitin in Transcription Regulation

2002 • 395 citations

Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter

1996 • 392 citations

p300 and p300/cAMP-response Element-binding Protein-associated Factor Acetylate the Androgen Receptor at Sites Governing Hormone-dependent Transactivation

2000 • 389 citations

Two Waves of Nuclear Factor κb Recruitment to Target Promoters

2001 • 386 citations

Proteasome-mediated Glucocorticoid Receptor Degradation Restricts Transcriptional Signaling by Glucocorticoids

2001 • 381 citations

Regulation of Transcriptional Activation Domain Function by Ubiquitin

2001 • 363 citations

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor α (RAR α ) and oncogenic RAR α fusion proteins

1999 • 359 citations

Androgen Receptor Phosphorylation

2002 • 353 citations

Direct Acetylation of the Estrogen Receptor α Hinge Region by p300 Regulates Transactivation and Hormone Sensitivity

2001 • 347 citations

Recruitment of a 19 S Proteasome Subcomplex to an Activated Promoter

2002 • 340 citations

Nuclear receptor coregulators: multiple modes of modification

2002 • 323 citations

Activation of Estrogen Receptor α by S118 Phosphorylation Involves a Ligand-Dependent Interaction with TFIIH and Participation of CDK7

2000 • 286 citations

The 19S Regulatory Particle of the Proteasome Is Required for Efficient Transcription Elongation by RNA Polymerase II

2001 • 266 citations

Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone.

1995 • 192 citations

XPD Mutations Prevent TFIIH-Dependent Transactivation by Nuclear Receptors and Phosphorylation of RARα

2002 • 192 citations

Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo

1999 • 190 citations

Tissue-specific and hormonal regulations of human prostate-specific glandular kallikrein

1992 • 187 citations

Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF

1997 • 179 citations

Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction

1999 • 171 citations

Ordered recruitment of histone acetyltransferases and the TRAP/Mediator complex to thyroid hormone-responsive promoters in vivo

2002 • 157 citations

Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RARgamma degradation and transactivation

2002 • 151 citations

Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors

2000 • 145 citations

The Subnuclear Three-dimensional Image Analysis of Androgen Receptor Fused to Green Fluorescence Protein

2001 • 135 citations

Androgen Receptor Interacts with the Positive Elongation Factor P-TEFb and Enhances the Efficiency of Transcriptional Elongation

2001 • 130 citations

Reciprocal Recruitment of DRIP/Mediator and p160 Coactivator Complexes in Vivo by Estrogen Receptor

2002 • 128 citations

The RING finger protein SNURF modulates nuclear trafficking of the androgen receptor

2000 • 118 citations

From Androgen Receptor to the General Transcription Factor TFIIH

2000 • 115 citations

A role for coactivators and histone acetylation in estrogen receptor alpha-mediated transcription initiation

2001 • 102 citations

Tip60 Is a Co-activator Specific for Class I Nuclear Hormone Receptors

2001 • 92 citations

Agonist and antagonist activities of hydroxyflutamide and casodex relate to androgen receptor stabilization

1996 • 88 citations

Androgen-receptor-interacting nuclear proteins

2000 • 85 citations

Interaction of Androgen Receptors with Androgen Response Element in Intact Cells

1997 • 81 citations

Ligand-independent activation of the androgen receptor by the differentiation agent butyrate in human prostate cancer cells.

2000 • 73 citations

Phosphorylation/Dephosphorylation of Androgen Receptor as a Determinant of Androgen Agonistic or Antagonistic Activity

1999 • 66 citations

Binding of TATA Binding Protein to a Naturally Positioned Nucleosome Is Facilitated by Histone Acetylation

2001 • 61 citations

Mechanisms of chromatin assembly and transcription

2002 • 60 citations

CDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p.

1996 • 54 citations

Different proportions of various prostate-specific antigen (PSA) and human kallikrein 2 (hK2) forms are present in noninduced and androgen-induced LNCaP cells

2000 • 47 citations

Evidence that an IRES within the Notch2 Coding Region Can Direct Expression of a Nuclear Form of the Protein

2000 • 47 citations

An androgen response element mediates LNCaP cell dependent androgen induction of the hK2 gene

2000 • 46 citations

Pure antiandrogens disrupt the recruitment of coactivator GRIP1 to colocalize with androgen receptor in nuclei

2002 • 36 citations

Molecular analysis of the prostate-specific antigen upstream gene enhancer

2001 • 18 citations