Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Neuronal NADPH diaphorase is a nitric oxide synthase.

1991 • 1,917 citations

Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues.

1991 • 1,872 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

Ca2 ⁺ Permeability of KA-AMPA—Gated Glutamate Receptor Channels Depends on Subunit Composition

1991 • 1,458 citations

Excitatory amino acid receptors in the vertebrate central nervous system.

1989 • 1,316 citations

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

1993 • 1,024 citations

The Neostriatal Mosaic: Multiple Levels of Compartmental Organization in the Basal Ganglia

1992 • 1,005 citations

Light and electron immunocytochemical localization of AMPA‐selective glutamate receptors in the rat brain

1992 • 988 citations

Differential loss of striatal projection neurons in Huntington disease.

1988 • 976 citations

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

1993 • 882 citations

Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

1987 • 881 citations

Excitatory amino acid receptors and synaptic plasticity

1990 • 872 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1976 • 832 citations

Physiological, morphological, and histochemical characterization of three classes of interneurons in rat neostriatum

1993 • 801 citations

Metabotropic glutamate receptors in brain function and pathology

1993 • 799 citations

Selective Sparing of a Class of Striatal Neurons in Huntington's Disease

1985 • 767 citations

Developmental changes in distribution of NMDA receptor channel subunit mRNAs

1992 • 718 citations

Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: an in situ hybridization histochemistry and fluorescent retrograde tracing study

1988 • 649 citations

Efferent projections of the subthalamic nucleus in the rat: Light and electron microscopic analysis with the PHA‐L method

1987 • 580 citations

AMPA glutamate receptor subunits are differentially distributed in rat brain

1993 • 574 citations

Biochemical evidence for glutamate as neurotransmitter in corticostriatal and corticothalamic fibres in rat brain

1981 • 547 citations

Projection subtypes of rat neostriatal matrix cells revealed by intracellular injection of biocytin

1990 • 547 citations

The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits

1992 • 537 citations

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

1992 • 521 citations

Contributions of Quisqualate and NMDA Receptors to the Induction and Expression of LTP

1988 • 512 citations

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease

1991 • 497 citations

Excitotoxic injury of the neostriatum: a model for Huntington's disease

1990 • 477 citations

II. Excitotoxic models for neurodegenerative disorders

1984 • 469 citations

Molecular Neurobiology of Glutamate Receptors

1992 • 436 citations

Glutamate receptor channels: novel properties and new clones

1992 • 427 citations

NADPH‐diaphorase: A selective histochemical marker for striatal neurons containing both somatostatin‐ and avian pancreatic polypeptide (APP)‐like immunoreactivities

1983 • 426 citations

NMDA Receptor Losses in Putamen from Patients with Huntington's Disease

1988 • 401 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

Organization of N‐methyl‐D‐aspartate glutamate receptor gene expression in the basal ganglia of the rat

1994 • 368 citations

Preferential loss of striato‐external pallidal projection neurons in presymptomatic Huntington's disease

1992 • 362 citations

Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus.

1994 • 339 citations

A glutamate receptor channel with high affinity for domoate and kainate.

1992 • 336 citations

Monosynaptic inputs to caudate neurons identified by intracellular injection of horseradish peroxidase

1976 • 313 citations

The differential expression patterns of messenger RNAs encoding non-N-methyl-d-aspartate glutamate receptor subunits (GluR1–4) in the rat brain

1993 • 304 citations

Increase of proenkephalin mRNA and enkephalin content of rat striatum after daily injection of haloperidol for 2 to 3 weeks.

1983 • 286 citations

Anatomic correlation of NMDA and 3H-TCP-labeled receptors in rat brain

1988 • 284 citations

Parvalbumin‐containing gabaergic interneurons in the rat neostriatum

1990 • 284 citations

The patterns of neurotransmitter and neuropeptide co-occurrence among striatal projection neurons: conclusions based on recent findings

1990 • 276 citations

The effects of excitatory amino acids on intracellular calcium in single mouse striatal neurons in vitro

1987 • 268 citations

Striatal neurons containing both somatostatin‐ and avian pancreatic polypeptide (APP)‐like immunoreactivities and NADPH‐diaphorase activity: A light and electron microscopic study

1983 • 267 citations

Kinetic analysis of interactions between kainate and AMPA: Evidence for activation of a single receptor in mouse hippocampal neurons

1991 • 263 citations

Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease

1987 • 253 citations

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats

1991 • 253 citations

Differential expression of three glutamate receptor genes in developing rat brain: an in situ hybridization study.

1991 • 252 citations

Contributory mechanisms in the causation of neurodegenerative disorders

1993 • 228 citations

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

1992 • 201 citations

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h

1993 • 192 citations

N-methyl-D-aspartate-type receptors mediate striatal 3H-acetylcholine release evoked by excitatory amino acids

1982 • 187 citations

l-Glutamate-evoked release of dopamine from synaptosomes of the rat striatum: Involvement of AMPA and N-methyl-d-aspartate receptors

1992 • 166 citations

Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7

1993 • 155 citations

Selective sparing of NADPH‐diaphorase neurons in neonatal hypoxia‐ischemia

1988 • 153 citations

Quantitative localization of AMPA/kainate and kainate glutamate receptor subunit immunoreactivity in neurochemically identified subpopulations of neurons in the prefrontal cortex of the macaque monkey

1993 • 146 citations

Molecular biology of glutamate receptors

1994 • 141 citations

Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists

1988 • 130 citations

Ischemic damage in the striatum of adult gerbils: Relative sparing of somatostatinergic and cholinergic interneurons contrasts with loss of efferent neurons

1990 • 108 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats

1993 • 104 citations

Quinolinic acid does not spare striatal neuropeptide Y-immunoreactive neurons

1987 • 98 citations

Relative Survival of Striatal Projection Neurons and Interneurons after Intrastriatal Injection of Quinolinic Acid in Rats

1994 • 94 citations

Intrastriatal Injections of Quinolinic Acid or Kainic Acid: Differential Patterns of Cell Survival and the Effects of Data Analysis on Outcome

1993 • 87 citations

Localization of ampa-selective excitatory amino acid receptor subunits in identified populations of striatal neurons

1994 • 82 citations

Quinolinate differentiates between forebrain and cerebellar NMDA receptors

1991 • 81 citations

Striatonigral projection neurons: A retrograde labeling study of the percentages that contain substance P or enkephalin in pigeons

1991 • 81 citations

What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies

1990 • 76 citations

Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques.

1991 • 66 citations

Nitric oxide synthase neurons in rat brain express more NMDA receptor mRNA than non-NOS neurons

1993 • 63 citations

Protection against post-ischemic behavioral pathology by the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX) in the gerbil

1991 • 60 citations

In Vitro Hypoxia Induces Expression of the NR2C Subunit of the NMDA Receptor in Rat Cortex and Hippocampus

1994 • 57 citations

Localization of Mn-superoxide dismutase (Mn-SOD) in cholinergic and somatostatin-containing neurons in the rat neostriatum

1991 • 52 citations

Glutamate-Mediated Excitotoxic Death of Cultured Striatal Neurons Is Mediated by Non-NMDA Receptors

1995 • 52 citations

Effects of postnatal hypoxia-ischemia on cholinergic neurons in the developing rat forebrain: choline acetyltransferase immunocytochemistry

1987 • 47 citations

Expression of N-methyl-d-aspartate receptor subunit NR1 messenger RNA by identified striatal somatostatin cells

1994 • 45 citations

d-[3H]aspartate and [14C]GABA uptake in the basal ganglia of rats following lesions in the subthalamic region suggest a role for excitatory amino acid but not GABA-mediated transmission in subthalamic nucleus efferents

1991 • 37 citations

Differential regulation by N-methyl-d-aspartate and non-N-methyl-d-aspartate receptors of acetylcholine release from the rat striatum in vivo

1995 • 37 citations

Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease

1985 • 35 citations

Pharmacological properties of the N-methyl-D-aspartate receptor system coupled to the evoked release of gamma-[3H] aminobutyric acid from striatal neurons in primary culture.

1990 • 32 citations

Protection by Two Non-NMDA Antagonists, NBQX and GYKI 52466 Against Selective Cell Loss following Transient Global Ischaemia (4VO) in the Rat

1992 • 29 citations

2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo

1994 • 20 citations

N-methyl-d-aspartate evokes the release of somatostatin from striatal interneurons in primary culture

1991 • 18 citations

Neonatal striatal NADPH-diaphorase neurons are vulnerable to quisqualate and its analogue α-amino-3-hydroxy-5-methyl-4-isoxazole proprionate (AMPA)

1991 • 10 citations

Delayed damage of striatal interneurons after cerebral ischemia in the gerbil

1994 • 7 citations