Molecular Neurobiology of Glutamate Receptors

The organization of behavior

1988 • 8,668 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Glutamate: A Neurotransmitter in Mammalian Brain

1984 • 1,981 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

The physiology of excitatory amino acids in the vertebrate central nervous system

1987 • 1,718 citations

Excitatory amino acid receptors in the vertebrate central nervous system.

1989 • 1,316 citations

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1990 • 1,234 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes

1990 • 925 citations

Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists

1990 • 905 citations

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

The role of divalent cations in the N‐methyl‐D‐aspartate responses of mouse central neurones in culture.

1988 • 810 citations

Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices

1990 • 803 citations

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

1988 • 798 citations

Identification of a Site in Glutamate Receptor Subunits That Controls Calcium Permeability

1991 • 774 citations

A new type of glutamate receptor linked to inositol phospholipid metabolism

1987 • 743 citations

A Physiological Mechanism for Hebb's Postulate of Learning

1973 • 711 citations

Glutamate activates multiple single channel conductances in hippocampal neurons

1987 • 691 citations

Presynaptic mechanism for long-term potentiation in the hippocampus

1990 • 691 citations

NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus

1989 • 654 citations

Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development

1990 • 646 citations

Excitatory amino acids in the brain - focus on NMDA receptors

1987 • 641 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

HIV-1 Coat Protein Neurotoxicity Prevented by Calcium Channel Antagonists

1990 • 595 citations

A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties

1990 • 581 citations

Voltage dependence of NMDA-activated macroscopic conductances predicted by single-channel kinetics

1990 • 568 citations

Glutamate-operated channels: Developmentally early and mature forms arise by alternative splicing

1991 • 560 citations

Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain

1991 • 524 citations

Analysis of excitatory synaptic action in pyramidal cells using whole‐cell recording from rat hippocampal slices.

1990 • 505 citations

Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones.

1990 • 498 citations

The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography

1982 • 481 citations

Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells

1991 • 461 citations

Glutamate receptor desensitization and its role in synaptic transmission

1989 • 459 citations

Tonic Activation of NMDA Receptors by Ambient Glutamate Enhances Excitability of Neurons

1989 • 434 citations

Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons

1987 • 420 citations

Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate and blockade of desensitization by con A

1990 • 420 citations

Ionic Channels and Their Regulation by G Protein Subunits

1990 • 413 citations

A long-term depression of AMPA currents in cultured cerebellar purkinje neurons

1991 • 405 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices

1990 • 396 citations

Modulation of ion channel activity: a key function of the protein kinase C enzyme family.

1989 • 338 citations

Excitatory amino acids and neuropsychiatrie disorders

1989 • 327 citations

NMDA receptor antagonists disrupt the retinotectal topographic map

1989 • 293 citations

Mechanisms of visual plasticity: Hebb synapses, NMDA receptors, and beyond

1991 • 274 citations

Hippocampal synaptic plasticity and NMDA receptors: a role in information storage?

1990 • 259 citations

Glutamate receptors of rod bipolar cells are linked to a cyclic GMP cascade via a G-protein

1990 • 249 citations

Decreased hippocampal expression of a glutamate receptor gene in schizophrenia

1991 • 241 citations

Quisqualate Activates a Rapidly Inactivating High Conductance Ionic Channel in Hippocampal Neurons

1989 • 237 citations

Postsynaptic NMDA receptor-mediated calcium accumulation in hippocampal CAl pyramidal cell dendrites

1990 • 234 citations

N‐methyl‐D‐aspartate‐activated channels of mouse central neurones in magnesium‐free solutions.

1988 • 230 citations

Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors

1990 • 226 citations

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.

1988 • 223 citations

Ketamine, Phencyclidine, and MK‐801 Protect Against Kainic Acid‐Induced Seizure‐Related Brain Damage

1990 • 217 citations

A kinetic analysis of the modulation of N‐methyl‐D‐aspartic acid receptors by glycine in mouse cultured hippocampal neurones.

1990 • 216 citations

Permeation of Calcium Ions Through Non-NMDA Glutamate Channels in Retinal Bipolar Cells

1991 • 209 citations

Mechanisms of blockade of excitatory amino acid receptor channels

1990 • 199 citations

Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine

1991 • 198 citations

Sequence and expression of a frog brain complementary DNA encoding a kainate-binding protein

1989 • 181 citations

Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate

1990 • 178 citations

Effect ofl-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies

1990 • 176 citations

Glycine is a coagonist at the NMDA receptor/channel complex

1990 • 172 citations

Patch clamp analysis of excitatory synaptic currents in granule cells of rat hippocampus.

1991 • 159 citations

Properties of excitatory postsynaptic currents recorded in vitro from rat hippocampal interneurones.

1990 • 153 citations

Activity-dependent plasticity in the visual systems of frogs and fish

1991 • 153 citations

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N‐methyl‐D‐aspartate receptor.

1990 • 139 citations

Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel

1991 • 127 citations

Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat

1991 • 126 citations

Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems

1990 • 123 citations

Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism

1990 • 116 citations

The non-NMDA receptors: types, protein structure and molecular biology

1990 • 115 citations

Glutamate and kainate receptors induced by rat brain messenger RNA in Xenopus oocytes

1984 • 110 citations

Dark-rearing delays the loss of NMDA-receptor function in kitten visual cortex

1991 • 108 citations

A kainic acid receptor from frog brain purified using domoic acid affinity chromatography.

1988 • 88 citations

On the multiple‐conductance single channels activated by excitatory amino acids in large cerebellar neurones of the rat.

1989 • 88 citations

Enhancement of kainate-gated currents in retinal horizontal cells by cyclic AMP-dependent protein kinase

1989 • 84 citations

Restoration of the Plasticity of Binocular Maps by NMDA After the Critical Period in Xenopus

1990 • 83 citations

Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type.

1990 • 78 citations

Different classes of glutamate receptors mediate distinct behaviors in a single brainstem nucleus.

1989 • 70 citations

Do endogenous excitatory amino acids influence striatal dopamine release?

1991 • 69 citations

Quisqualate‐ and NMDA‐sensitive [³H]glutamate binding in primate brain

1990 • 52 citations

Whole‐cell current noise produced by excitatory and inhibitory amino acids in large cerebellar neurones of the rat.

1989 • 45 citations

Immunochemical characterization of brain synaptic membrane glutamate-binding proteins.

1990 • 39 citations

Evidence for a single glutamate receptor of the ionotropic kainate/quisqualate type.

1989 • 35 citations

Computational Implications of NMDA Receptor Channels

1990 • 31 citations

Activation of N-methyl-d-aspartate (NMDA) receptors augments repolarizing responses in lamprey spinal neurons

1989 • 20 citations

Phosphorylation of the 49-kDa putative subunit of the chick cerebellar kainate receptor and its regulation by kainatergic ligands.

1990 • 20 citations

Patch-clamp recording from single glutamate-receptor channels

1987 • 20 citations

Immune labeling and purification of a 71-kDa glutamate-binding protein from brain synaptic membranes

1988 • 20 citations

Partial characterization of kainic acid-induced striatal dopamine release using in vivo microdialysis

1991 • 19 citations

7‐Chlorokynurenic acid blocks NMDA receptor‐induced fictive locomotion in lamprey—evidence for a physiological role of the glycine site

1991 • 9 citations

Deleted Work

1955 • 0 citations