Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(β5i) incorporation into 20 S proteasomes 1 1Edited by R. Huber

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

1995 • 1,513 citations

The ubiquitin-proteasome pathway: on protein death and cell life

1998 • 1,401 citations

The Active Sites of the Eukaryotic 20 S Proteasome and Their Involvement in Subunit Precursor Processing

1997 • 506 citations

Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits

1998 • 430 citations

Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival.

1991 • 421 citations

Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

1996 • 390 citations

Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly

1998 • 316 citations

The catalytic sites of 20S proteasomes and their role in subunit maturation: A mutational and crystallographic study

1999 • 296 citations

The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

1989 • 277 citations

Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase

1992 • 235 citations

The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome

1997 • 208 citations

Critical elements in proteasome assembly

1994 • 203 citations

Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

1996 • 195 citations

Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.

1996 • 191 citations

Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits

1997 • 181 citations

Efficient Generation of a Hepatitis B Virus Cytotoxic T Lymphocyte Epitope Requires the Structural Features of Immunoproteasomes

2000 • 161 citations

20 S proteasomes are assembled via distinct precursor complexes processing of LMP2 and LMP7 proproteins takes place in 13–16 S preproteasome complexes

1994 • 146 citations

Proteasome β-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function

1999 • 131 citations

Maturation of mammalian 20 S proteasome: purification and characterization of 13 S and 16 S proteasome precursor complexes

1997 • 112 citations

Evidence Indicating that the Human Proteasome is a Complex Dimer

1993 • 97 citations

Dissecting the assembly pathway of the 20S proteasome

1997 • 94 citations

Human proteasomes analysed with monoclonal antibodies

1995 • 91 citations

The Human α-Type Proteasomal Subunit HsC8 Forms a Double Ringlike Structure, but Does Not Assemble into Proteasome-like Particles with the β-Type Subunits HsDelta or HsBPROS26

1997 • 89 citations

PRE3, highly homologous to the human major histocompatibility complex‐linked LMP2 (RING12) gene, codes for a yeast proteasome subunit necessary for the peptidylglutamyl‐peptide hydrolyzing activity

1994 • 80 citations

Alternate promoters direct stress‐induced transcription of the Bacillus subtilis clpC operon

1996 • 75 citations

Biogenesis of eukaryotic 20S proteasomes: the complex maturation pathway of a complex enzyme

1997 • 51 citations

The human proteasome subunit HsN3 is located inthe inner rings of the complex dimer

1995 • 50 citations

Sequence information within proteasomal prosequences mediates efficient integration of β-subunits into the 20 s proteasome complex

1999 • 37 citations

Mutational analysis of subunit iβ2 (MECL‐1) demonstrates conservation of cleavage specificity between yeast and mammalian proteasomes

1999 • 33 citations

Cloning and characterization of mouse Lmp3 cDNA, encoding a proteasome β subunit

1997 • 12 citations