Sequence information within proteasomal prosequences mediates efficient integration of β-subunits into the 20 s proteasome complex

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

1995 • 1,513 citations

The Active Sites of the Eukaryotic 20 S Proteasome and Their Involvement in Subunit Precursor Processing

1997 • 506 citations

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

1993 • 453 citations

Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid.

1986 • 437 citations

Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits

1998 • 430 citations

Proteasomes: multicatalytic proteinase complexes

1993 • 395 citations

Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

1996 • 390 citations

Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly

1998 • 316 citations

Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase

1992 • 235 citations

Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.

1994 • 220 citations

The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome

1997 • 208 citations

Critical elements in proteasome assembly

1994 • 203 citations

Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

1996 • 195 citations

Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.

1996 • 191 citations

Pro‐sequence‐assisted protein folding

1995 • 184 citations

Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits

1997 • 181 citations

The role of pro regions in protein folding

1993 • 174 citations

Propeptide of carboxypeptidase Y provides a chaperone-like function as well as inhibition of the enzymatic activity.

1991 • 173 citations

Incorporation of major histocompatibility complex – encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon‐γ

1995 • 167 citations

Proteasome Subunits X and Y Alter Peptidase Activities in Opposite Ways to the Interferon-γ-induced Subunits LMP2 and LMP7

1996 • 164 citations

Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport

1995 • 129 citations

Subunit arrangement in the human 20S proteasome

1997 • 121 citations

Maturation of mammalian 20 S proteasome: purification and characterization of 13 S and 16 S proteasome precursor complexes

1997 • 112 citations

Dissecting the assembly pathway of the 20S proteasome

1997 • 94 citations

The Human α-Type Proteasomal Subunit HsC8 Forms a Double Ringlike Structure, but Does Not Assemble into Proteasome-like Particles with the β-Type Subunits HsDelta or HsBPROS26

1997 • 89 citations

Molecular cloning of the mouse proteasome subunits MC14 and MECL‐1: reciprocally regulated tissue expression of interferon‐γ‐modulated proteasome subunits

1997 • 67 citations

Biogenesis of eukaryotic 20S proteasomes: the complex maturation pathway of a complex enzyme

1997 • 51 citations

The Structural and Functional Organization of Intramolecular Chaperones: The N-Terminal Propeptides Which Mediate Protein Folding1

1994 • 47 citations

The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter.

1997 • 39 citations

Newly Identified Pair of Proteasomal Subunits Regulated Reciprocally by Interferon γ

1997 • 39 citations

Delineation of the subunit composition of human proteasomes using antisera against the major histocompatibility complex-encoded LMP2 and LMP7 subunits.

1994 • 20 citations

Molecular and serological analysis of polymorphisms in the murine major histocompatibility complex-encoded proteasome subunits, LMP-2 and LMP-7.

1996 • 20 citations

Cloning and characterization of mouse Lmp3 cDNA, encoding a proteasome β subunit

1997 • 12 citations

Characterization and mapping of the gene encoding mouse proteasome subunit DELTA (Lmp19)

1995 • 12 citations

Cloning and sequencing of a murine cDNA encoding the proteasome component C5

1995 • 7 citations

Studies on rLMP7, a β-Subunit of the Multicatalytic Proteinase

1997 • 2 citations