A deletion map of the human immunoglobulin heavy chain variable region.

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1981 • 959 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

1984 • 644 citations

Early Restriction of the Human Antibody Repertoire

1987 • 546 citations

Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus.

1988 • 432 citations

Developmentally Controlled Expression of Immunoglobulin V _H Genes

1985 • 349 citations

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

1987 • 346 citations

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

1986 • 332 citations

Organization of human immunoglobulin heavy chain diversity gene loci.

1988 • 317 citations

Organization of immunoglobulin heavy chain genes and allelic deletion model.

1978 • 297 citations

Organization and evolution of variable region genes of the human immunoglobulin heavy chain

1986 • 227 citations

Human immunoglobulin D segments encoded in tandem multigenic families

1981 • 219 citations

Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region.

1980 • 199 citations

Translocation of immunoglobulin VH genes in Burkitt lymphoma.

1982 • 196 citations

A novel family of variable region genes of the human immunoglobulin heavy chain

1987 • 187 citations

VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments.

1986 • 186 citations

Developmentally regulated and strain-specific expression of murine VH gene families.

1988 • 186 citations

Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.

1983 • 165 citations

Limiting dilution analysis of the B cell compartment in human bone marrow

1986 • 162 citations

The use of chromosomal translocations to study human immunoglobulin gene organization: mapping DH segments within 35 kb of the C mu gene and identification of a new DH locus.

1988 • 155 citations

MECHANISM AND DEVELOPMENTAL PROGRAM OF IMMUNOGLOBULIN GENE REARRANGEMENT IN MAMMALS

1989 • 144 citations

Genes for immunoglobulin heavy chains and for α1-antitrypsin are localized to specific regions of chromosome 14q

1982 • 139 citations

The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters.

1988 • 116 citations

Organization and evolution of immunoglobulin VH gene subgroups.

1982 • 114 citations

The physical organization of the human immunoglobulin heavy chain gene complex.

1990 • 113 citations

Immunoglobulin V_H gene expression in human B cell lines and tumors: biased V_H gene expression in chronic lymphocytic leukemia

1989 • 112 citations

Human heavy-chain variable region gene family nonrandomly rearranged in familial chronic lymphocytic leukemia.

1987 • 109 citations

Novel rearrangements at the immunoglobulin D locus. Inversions and fusions add to IgH somatic diversity.

1989 • 103 citations

Physical linkage of a human immunoglobulin heavy chain variable region gene segment to diversity and joining region elements.

1988 • 103 citations

Adult B-cell repertoire is biased toward two heavy-chain variable-region genes that rearrange frequently in fetal pre-B cells.

1987 • 100 citations

Preferential Expression of V_H5 and V_H6 Immunoglobulin Genes in Early Human B‐Cell Ontogeny

1989 • 86 citations

Dispersed localization of D segments in the human immunoglobulin heavy-chain locus.

1988 • 81 citations

Rearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining region.

1984 • 78 citations

Early human IgH gene assembly in Epstein-Barr virus-transformed fetal B cell lines. Preferential utilization of the most JH-proximal D segment (DQ52) and two unusual VH-related rearrangements.

1989 • 67 citations

Prevalence and polymorphism of human VH3 genes.

1990 • 65 citations

Heterogeneity in the human Ig VH locus.

1989 • 65 citations

Characterization of Productive and Sterile Transcripts from the Immunoglobulin Heavy-Chain Locus: Processing of μ_m and μ_s mRNA

1983 • 63 citations

Organization of the murine immunoglobulin VH complex in the inbred strains.

1987 • 59 citations

Clonal and molecular characteristics of the human IgE-committed B cell subset.

1989 • 57 citations

Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes.

1984 • 56 citations

Strain-dependent expression of VH gene families.

1988 • 53 citations

A V_H gene is located within 95 Kb of the human immunoglobulin heavy chain constant region genes

1988 • 51 citations

Immunoglobulin V_H region genes of the mouse are organized in overlapping clusters

1987 • 51 citations

At least five d_h genes of human immunoglobulin heavy chains are encoded in 9‐kilobase dna fragments

1988 • 50 citations

In-frame single codon deletion in the Mmalton deficiency allele of alpha 1-antitrypsin.

1989 • 47 citations

Megabase inversions in the human genome as physiological events

1990 • 42 citations

Molecular characterization of the J558 family of heavy chain variable region gene segments

1988 • 40 citations

Polymorphisms in human H chain V region genes from the VHIII gene family.

1989 • 38 citations

VH gene family utilization is regulated by a locus outside of the VH region.

1988 • 36 citations

Analysis of genetic variation reveals human immunoglobulin VH-region gene organization.

1988 • 34 citations

Human Immunoglobulin Heavy Chain Genes

1989 • 33 citations

Organization and Expression of the Mammalian Heavy-Chain Variable-Region Locus

1989 • 33 citations

Localization and genetic linkage of the human immunoglobulin heavy chain genes and the creatine kinase brain (CKB) gene: Identification of a hot spot for recombination

1991 • 31 citations

Organization of the Ig VH locus in mice and humans

1989 • 30 citations

A highly informative probe for two polymorphic Vh gene regions that contain one or more autoantibody-associated Vh genes.

1989 • 29 citations

Are anti-arsonate antibody N-segments selected at both the protein and the DNA level?

1986 • 24 citations

Organization of the murine immunoglobulin VH complex: Placement of two new VH families (VH10 and VH11) and analysis of VH family clustering and interdigitation

1990 • 23 citations

Immunoglobulin JH, C mu, and C gamma gene rearrangements in human B lymphocytes clonally transformed by Epstein-Barr virus.

1985 • 19 citations

Properties and heterogeneity of human fetal pre-B cells transformed by EBV.

1989 • 17 citations

Differential regulation of activation, clonal expansion, and antibody secretion in human B cells.

1985 • 17 citations

Concerted generation of Ig isotype diversity in human fetal bone marrow.

1989 • 16 citations

Phenotype, frequency, and EBV responsiveness of human marrow B and pre-B cells.

1986 • 16 citations

A method for two-dimensional DNA electrophoresis (2D-DE): Application to the immunoglobulin heavy chain variable region

1989 • 15 citations

RsaI polymorphism of a human immunoglobulin VH5 subclass locus

1988 • 14 citations

Apa I polymorphism of a human immunoglobin VH3 subclass locus

1987 • 12 citations

VH gene repertoire.

1990 • 10 citations